Podcast

Executive Insights for Life Sciences Innovators

Life Sciences, Science

Executive Insights features conversations with visionary leaders shaping the future of biotech, pharma, medtech, diagnostics, and tools. Hear from CEOs, entrepreneurs, and investors about building companies, raising capital, and driving innovation. Whether you are growing a startup or scaling a global life sciences business, these candid discussions deliver the insights you need to succeed.

Episodes
30
Releases
Every two weeks
Typical length
31 min
On air since
2025
Latest episode
3 days ago

Episodes

30 episodes, newest first

  1. Michael Fanous | SCANIMUS - Making Digital Pathology More Accessible

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Michael Fanous, Founder of SCANIMUS.

    Michael discusses how SCANIMUS combines continuous slide scanning with AI image reconstruction to make digital pathology more accessible. The conversation explores the practical barriers to digitization, including cost, complexity, and workflow fit, and how a compact imaging system could help bring digital tools to more researchers and laboratories.

    Michael also shares perspective on his transition from computational imaging research to entrepreneurship. He discusses how feedback from pathologists shapes product development, the importance of earning trust in AI-assisted imaging, and the challenges of moving from a working prototype to hardware that can be manufactured, shipped, and supported reliably. The conversation also examines how scientific founders balance affordability, funding, and the partnerships needed to support adoption.

    This episode was streamed live on YouTube on October 30, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    31 min
  2. Ryan Beal | Dyve Biosciences - Targeting Tumor Acidity to Advance Cancer Treatment

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Ryan Beal, M.D., Founder and CEO of Dyve Biosciences.

    Ryan discusses how Dyve is working to translate decades of research on tumor acidity into new therapeutic approaches for cancer. The conversation explores how an acidic tumor microenvironment can suppress immune function and limit treatment effectiveness, and how Dyve's transdermal drug delivery platform may offer a new way to address this longstanding challenge.

    Ryan also shares perspective from his career spanning medicine, pharmaceutical strategy, and biotechnology entrepreneurship. He discusses Dyve's evolution from drug delivery innovation toward oncology, its collaboration with Moffitt Cancer Center, and the challenges of advancing unconventional scientific approaches toward clinical development. The conversation also examines the importance of recognizing opportunities where established biology has yet to translate into practical therapies.

    This episode was streamed live on YouTube on October 19, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    29 min
  3. Mark Rutledge | World Precision Instruments - Advancing Preclinical Research Through Better Tools and Models

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Mark Rutledge, President and CEO of World Precision Instruments.

    Mark discusses how evolving research needs are reshaping the tools and technologies used in preclinical science. The conversation explores the growing importance of more standardized and physiologically relevant in vitro models, including organ-on-chip applications, as researchers look for better ways to generate meaningful data earlier in development.

    Mark also shares perspective from his leadership experience across diagnostics, life sciences tools, and commercial organizations. He discusses how World Precision Instruments evaluates where to innovate, the role of customer insight in product development, and the challenges of leading an established scientific instrumentation company through changing research and market expectations.

    This episode was streamed live on YouTube on September 28, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    27 min
  4. Justin Byers | Axio BioPharma - Building the Data Foundation for AI-Ready Biomanufacturing

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Justin Byers, Founder and CEO of Axio BioPharma.

    Justin discusses why the next generation of AI-enabled biomanufacturing depends on something more fundamental than better algorithms: better access to structured, contextualized process data. The conversation explores how fragmented information across labs, manufacturing sites, sponsors, and external partners can slow development, complicate tech transfer, and limit the value organizations can extract from AI.

    Justin also shares perspective from his career across analytical science, process development, commercialization, and company building. He discusses Axio BioPharma’s approach to connecting real-world laboratory execution with broader process knowledge, the challenges of transferring knowledge across organizational boundaries, and what life sciences leaders should consider as they prepare their manufacturing operations for more effective use of AI.

    This episode was streamed live on YouTube on September 14, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    27 min
  5. Dhruv Patwardhan | LuminOne - Accountable AI for Life Sciences Commercial Teams

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Dhruv Patwardhan, Founder of LuminOne.

    Dhruv discusses how AI can improve commercial decision-making in life sciences by helping teams make better use of fragmented market, account, and customer signals. The conversation explores where AI is genuinely useful today, why many implementations stall after the pilot stage, and how leaders can distinguish practical workflow improvements from impressive demonstrations that fail to change day-to-day execution.

    Dhruv also shares perspective from more than a decade in life sciences commercial leadership, including lessons on workflow design, source traceability, human oversight, and accountability. He explains why AI should support rather than replace human judgment, and what CEOs and commercial leaders should consider as AI becomes more deeply embedded in commercial organizations.

    This episode was streamed live on YouTube on August 28, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    32 min
  6. Pawel Krysiak | Jaya Biosciences - Gene Therapy for Neurodegeneration

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Pawel Krysiak, President & CEO of Jaya Biosciences.

    Pawel discusses JayaBio’s work to develop CNS-directed gene therapies for genetically defined neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and frontotemporal dementia. The conversation explores JayaBio’s focus on lysosomal enzyme gene heterozygosity and how this approach may help identify patient subpopulations within diseases historically treated as broad, heterogeneous conditions.

    Pawel also shares perspective from more than 20 years across neurodegeneration, oncology, rare diseases, commercialization, market access, and company building, including lessons from orphan drug launches and the challenge of advancing differentiated science toward clinical development.

    This episode was streamed live on YouTube on June 29, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    35 min
  7. David Pass | AltrixBio - Gut-Targeted Oral Therapy for Diabetes and Obesity

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with David Pass, CEO and President of AltrixBio.

    David discusses AltrixBio’s work to advance AJN003, a once-daily, oral, gut-targeted therapeutic candidate being developed for type 2 diabetes, obesity, and related cardiometabolic conditions. The conversation explores how AltrixBio’s approach is inspired by the metabolic effects observed after bariatric surgery, and how a non-systemic oral therapy could address important gaps in today’s treatment landscape.

    David also shares perspective from more than 25 years across diabetes, obesity, cardiovascular disease, pharma, biotech, and digital health, including lessons from commercial leadership, company building, and advancing differentiated science toward the clinic.

    This episode was streamed live on YouTube on June 15, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    21 min
  8. Dave Gallup | EMPIRI - Functional Precision Oncology and Live Tumor Tissue Drug Response

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Dave Gallup, Co-Founder and CEO of EMPIRI, an oncology platform company advancing functional precision oncology through its E-slice platform.

    Dave discusses how EMPIRI is using live human tumor tissue to measure drug response while preserving native tumor architecture and the tumor microenvironment. The conversation explores how E-slice may complement genomic and molecular profiling, help bridge the translational gap between preclinical models and clinical outcomes, and support better decision-making in oncology drug development.

    Dave also shares his path from building biological analysis businesses to co-founding EMPIRI, including lessons from scaling complex technical platforms, earning market trust, and balancing scientific rigor with commercial execution.

    This episode covers functional precision oncology, live tumor tissue assays, oncology drug development, translational science, and the future role of empirical drug response data in cancer research and care.

    This episode was streamed live on YouTube on May 29, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    30 min
  9. Anil Goyal | IMMvention Therapeutix - Collaborations & Building Biotech Innovation Ecosystems

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Dr. Anil Goyal, Co-Founder and CEO of IMMvention Therapeutix, a VC-backed biotechnology company developing globally accessible therapies for rare and chronic diseases, including sickle cell disease and Friedreich’s ataxia.

    Anil shares insights from nearly 30 years in biotechnology leadership spanning company formation, fundraising, strategic partnerships, and therapeutic innovation across multiple modalities and disease areas. The conversation explores Immvention’s scientific approach, the realities of building emerging biotech companies in today’s funding environment, and the balance between scientific ambition and operational discipline.

    They also discuss Immvention’s strategic collaboration with Novo Nordisk focused on developing oral therapies for sickle cell disease and other chronic diseases, including what partnerships like these can signal about platform validation and long-term development strategy.

    Beyond his work in biotechnology, Anil is also a passionate ecosystem builder and co-founder of the OpenDoors Group, a nonprofit organization focused on increasing equity, diversity, and access for the next generation of life sciences entrepreneurs and innovators. The discussion also touches on North Carolina’s growing R&D ecosystem and the importance of regional innovation clusters in advancing life sciences.

    This episode was streamed live on YouTube on May 18, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    33 min
  10. Stan Watowich | Ridgeline Therapeutics - Targeting Aging Biology and Chronic Disease

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, Don Alexander speaks with Stan Watowich, Founder and CEO of Ridgeline Therapeutics and Professor of Biochemistry and Molecular Biology at the University of Texas Medical Branch.

    Stan shares his journey from academic science to biotech company building, and how Ridgeline is developing small molecule therapies aimed at improving how we age and treat chronic disease. The conversation explores the company’s focus on NNMT, a key regulator of cellular energetics, and the broader opportunity to address age-linked conditions through targeted drug discovery.

    They also discuss the realities of translating academic research into commercial success, prioritizing programs in a constrained funding environment, and what it takes to build a company around high-conviction science.

    This episode was streamed live on YouTube on May 1, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    32 min
  11. Michael Heltzen | eXoZymes – AI-Enabled Cell-Free Biomanufacturing and the Future of Enzyme Engineering

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Michael Heltzen, CEO of eXoZymes, a publicly traded biotechnology company developing AI-enabled, cell-free biomanufacturing platforms designed to expand what is possible with enzyme engineering.

    Michael discusses the company’s thesis that producing complex molecules outside living cells may allow greater control, scalability, and speed compared to traditional biologic manufacturing approaches.

    We explore how advances in artificial intelligence are helping identify and optimize enzyme pathways, the strategic considerations involved in building a platform company in today’s capital environment, and what differentiates cell-free systems from more established synthetic biology approaches.

    We also discuss the realities of scaling a publicly traded life sciences company, how leaders balance scientific ambition with commercial discipline, and where cell-free biomanufacturing could create meaningful impact across nutraceutical, pharmaceutical, and industrial markets.This episode was streamed live on YouTube on April 17, 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

    43 min
  12. Charles Legg | CureLab Oncology – Advancing Immuno-Oncology Through Targeting the Tumor Microenvironment

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Charles Legg of CureLab Oncology, a biotechnology company developing novel immuno-oncology therapies designed to more precisely modulate immune pathways within the tumor microenvironment.

    Charles shares his perspective on how immunotherapy continues to evolve beyond first-generation checkpoint inhibitors and why a deeper understanding of tumor biology may lead to more durable and broadly effective cancer treatments. We discuss the scientific rationale behind targeting immune signaling pathways, the challenges of translating complex biology into therapeutic development programs, and how emerging platform approaches may shape the future of oncology innovation.

    We also explore the realities of building oncology companies in today’s capital environment, including capital efficiency, prioritization of development milestones, and how biotechnology leaders communicate complex scientific strategies to investors and partners.

    This episode was streamed live on YouTube on April 6 2026. Learn more at ⁠⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠⁠.

    30 min
  13. Christopher Gropp | Trialogics – Modernizing Clinical Trials Through AI, Real-Time Data, and Integrated Technology

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Christopher Gropp, Founder and CEO of Trialogics, a clinical trial technology company developing integrated platforms designed to improve how clinical research data is captured, managed, and utilized across global studies.

    Chris shares his journey building technology solutions for clinical research and explains why many trials still rely on fragmented systems that create operational inefficiencies for sponsors, CROs, and clinical sites. He discusses Trialogics’ approach to integrating eConsent, IRT/IWRS, ePRO/eCOA, and remote device management to support decentralized trials and enable real-time patient data collection.

    We explore the operational challenges of scaling technology in regulated environments, the growing role of AI in clinical trial management, and how modern platforms are helping sponsors run more efficient, patient-centered studies.

    This episode was streamed live on YouTube on March 23, 2026. Learn more at ⁠⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠⁠.

    33 min
  14. Chris Hoyt | KeifeRx – Building Biotech Companies Around Academic Drug Discovery

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Chris Hoyt, CEO of KeifeRx, a pre-clinical stage biotechnology company developing small molecule therapies for neurodegenerative diseases based on technology licensed from Georgetown University.

    Chris shares his journey as an entrepreneurial executive who has launched, funded, and scaled venture-backed companies across multiple industries before entering biotechnology. He discusses how those experiences translate to building a drug development company and the strategic decisions involved in turning promising academic discoveries into IND enabled programs.

    We explore the challenges of funding and scaling early-stage biotech companies, the importance of capital discipline in today’s market environment, and how leaders evaluate scientific opportunities when building new biotechnology ventures.

    This episode was streamed live on YouTube on March 9, 2026. Learn more at ⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠.

    28 min
  15. Ben Scruggs | Altis Biosystems – Engineering Predictive Human Gut Models for Drug Development

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Ben Scruggs, the CEO of Altis Biosciences, a biotechnology company developing advanced human intestinal tissue platforms designed to improve the predictability of drug development.

    Ben explains how Altis’ RepliGut® platform addresses long-standing limitations in traditional preclinical gut models, which often fail to replicate human physiology and contribute to costly downstream clinical setbacks. He shares how the company is building scalable, functional human intestinal tissue systems to better model drug absorption, metabolism, toxicity, and inflammatory disease.

    We explore the discipline required to commercialize complex biology, the realities of scaling a platform biotechnology company, and how improving translational models can enhance capital efficiency across the pharmaceutical industry. Ben also offers perspective on leadership in deep science ventures, partnering with pharma, and positioning infrastructure technologies for long-term impact.

    This episode was streamed live on YouTube on February 23, 2026. Learn more at ⁠⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠⁠.

    36 min
  16. Murat Croci | Ibex Biosciences – Translating Breakthrough Science into Clinical-Stage Therapies

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Murat Croci, Co-CEO of Ibex Biosciences, a biotechnology company developing novel therapies to address major unmet medical needs in oncology and infectious disease.

    Murat discusses how Ibex is advancing high-conviction therapeutic programs from preclinical success toward the clinic, and the discipline required to translate strong scientific data into IND-ready assets. He shares insights from his career across biotechnology, operations, and company leadership, and how taking personal capital risk alongside investors shapes his approach to execution and decision-making.

    We explore the realities of early-stage drug development, balancing portfolio focus with optionality, and the challenges founders face as programs transition from discovery into clinical development. Murat also offers his perspective on leadership under risk and what it takes to build durable biotech companies in today’s funding environment.

    This episode was streamed live on YouTube on February 6, 2026. Learn more at ⁠⁠⁠⁠genecoda.com⁠⁠⁠⁠.

    28 min
  17. Gitte Pedersen | Genomic Expression – RNA Diagnostics and Transforming Precision Oncology

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Gitte Pedersen, founder and CEO of Genomic Expression, a life sciences company focused on advancing RNA-based diagnostics to improve cancer care.

    Gitte discusses how Genomic Expression is applying RNA sequencing and data-driven diagnostics to help clinicians identify the most effective treatment options for individual cancer patients. She shares insights from her career journey, spanning corporate strategy, investment, and entrepreneurship, and how her multidisciplinary background has shaped the company’s mission-driven approach to innovation.

    We explore the challenges of translating complex genomic data into clinically actionable tools, the realities of scaling a diagnostics company within healthcare systems, and Gitte’s perspective on the future of precision oncology and RNA-based diagnostics.

    This episode was streamed live on YouTube on January 23, 2026. Learn more at ⁠⁠⁠genecoda.com⁠⁠⁠.

    26 min
  18. Jason Kralic | Tellus Therapeutics – Translational Biotech Platforms and Advancing Therapies for Neonatal Brain Injury

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Jason Kralic, CEO and co-founder of Tellus Therapeutics, a biotechnology company focused on developing novel therapies for neonatal brain injury.

    Jason discusses how Tellus is building a translational biotech platform grounded in strong biological insight and disciplined execution, with a clear focus on addressing one of the most complex and underserved patient populations in medicine.

    He shares insights from his career journey as a neuropharmacologist and life sciences business development leader, including how his experience in large pharma and biotech informs the way he evaluates scientific risk, platform focus, and company strategy.

    We explore the challenges of translating science into the clinic, the realities of capital strategy and timing in today’s funding environment, and Jason’s perspective on what it takes to build biotech companies designed to endure.

    This episode was streamed live on YouTube on January 9, 2026. Learn more at ⁠⁠genecoda.com⁠⁠.

    31 min
  19. Karthik Sriram | Parabilis Medicines – Strategic Finance and the Helicon™ Platform Shaping the Future of Peptide Therapeutics

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Karthik Sriram, Vice President of Financial Planning & Analysis at Parabilis Medicines, a biopharmaceutical company developing next-generation peptide therapeutics through its innovative Helicon™ platform.

    Karthik discusses how Parabilis is applying platform science and strategic financial planning to advance medicines designed to deliver extraordinary outcomes for patients. He shares insights from his career journey, transitioning from biomedical engineering into corporate strategy and biotech finance, and highlights how FP&A plays a central role in aligning scientific priorities with operational execution.

    We explore the company’s vision for the Helicon™ platform, the opportunities and challenges of scaling a clinical-stage organization, and the broader trends shaping the future of peptide therapeutics and biotech company-building.

    This episode was streamed live on YouTube on December 8, 2025.Learn more at ⁠genecoda.com⁠.

    30 min
  20. Jim Buck | Medcura – Advancing Surgical Safety Through Innovative Hemostatic Solutions

    Show notes

    In this episode of Executive Insights for Life Sciences Innovators, we speak with Jim Buck, President & CEO of Medcura, a medical device company advancing surgical safety through innovative hemostatic and wound treatment solutions.

    Jim discusses how Medcura is addressing one of healthcare’s most persistent challenges, rapid and reliable bleeding control, through a platform built on biocompatible, naturally derived polymers. He shares insights from his leadership journey, the company’s path from R&D to commercialization, and how Medcura’s technology is helping surgeons and patients achieve better outcomes in both surgical and wound care settings.

    This episode was streamed live on YouTube on October 6, 2025.

    Learn more at genecoda.com.

    31 min

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