Science@UH

Stephen Carpenter, MD, PhD, discusses the challenges of preventing and treating TB as well as the limitations of current vaccines, the role of memory T cells in controlling infection, and promising discoveries that could shape the next generation of tuberculosis vaccines.

• Learn more about Daniel Simon, MD
• Learn more about Stephen Carpenter, MD, PhD
• View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

University Hospitals Reproductive Endocrinology and Infertility specialists, Rebecca Flyckt, MD, and Kathryn Coyne, MD, discuss a groundbreaking FDA-approved clinical trial exploring ovarian tissue transplantation between sisters. They explain how the procedure works, who may benefit and how this innovative approach could restore fertility, hormone function and hope for women facing early menopause.

• Learn more about Daniel Simon, MD
• Learn more about Rebecca Flyckt, MD
• Learn more about Kathryn Coyne, MD
• View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Discover how a target identified in colon cancer research led to an unexpected opportunity to protect brain cells and preserve cognition in mouse models of Alzheimer’s and head trauma. Sanford Markowitz, MD, PhD, and Andrew Pieper, MD, PhD, describe the translational path, mechanistic insights into neuroinflammation and neurogenesis, and what’s needed for human trials.

• Learn more about Daniel Simon, MD
• Learn more about Andrew Pieper, MD, PhD
• Learn more about Sanford Markowitz, MD, PhD
• View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Adonis Hijaz, MD and Goutham Rao, MD discuss the reasons why urinary incontinence is underreported and actionable strategies clinicians can use to start the conversation in primary care. They outline the EMPOWER model, from large-scale screening to nurse navigators and pelvic floor physical therapy, and why that pathway increases treatment rates.

• Learn more about Daniel Simon, MD
• Learn more about Adonis Hijaz, MD
• Learn more about Goutham Rao, MD
• View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Explore the rapidly evolving world of CAR T-cell therapy and how scientists are reengineering the immune system to fight disease. Drs. David Wald and Reshmi Parameswaran discuss breakthroughs in cancer immunotherapy, including faster manufacturing, next‑generation CAR T-cell design, and efforts to expand these therapies from blood cancers to solid tumors and autoimmune diseases. This conversation highlights the promise and challenges of bringing these innovative treatments to patients.

• Learn more about Daniel Simon, MD
• Learn more about David Wald, MD, PhD
• Learn more about Reshmi Parameswaran, PhD, MS
• View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

The pace of change in cardiometabolic medicine is accelerating. Ian Neeland, MD, breaks down the latest innovations in incretin therapies, from oral medications to cutting-edge combinations, and what they mean for weight loss, heart health, and long-term patient care.

• Learn more about Daniel Simon, MD
• Learn more about Ian Neeland, MD
• View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Matthew Anderson, MD, PhD, and Tyler Miller, MD, PhD, discuss how immune biology is reshaping neuroscience - from autism and obesity to CAR T cell therapies for glioblastoma and the challenge of crossing the blood brain barrier.

• Learn more about Daniel Simon, MD
• Learn more about Matthew Anderson, MD, PhD
• Learn more about Tyler Miller, MD, PhD
• View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Jennifer Villwock, MD, explains the neurocircuitry of smell, her rapid essential-oil–based AROMA test, and how olfactory dysfunction can inform clinical care and research spanning sinonasal disease, post-viral loss, and cognitive health.

• Learn more about Daniel Simon, MD
• Learn more about Jennifer Villwock, MD
• View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Molly McVoy, MD, dives into the mental health crisis affecting teens, why anxiety and depression have risen dramatically, and shares breakthrough research using EEG biomarkers and self-management programs that help teens build resilience.

• Learn more about Daniel Simon, MD
• Learn more about Molly McVoy, MD
• NEW! View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Theodoros Teknos, MD, and Gary Schwartz, MD, discuss how the recent $25.5 million NCI grant renewal solidifies Case Comprehensive Cancer Center as a powerhouse consortium delivering cutting-edge clinical trials, early detection and community-focused cancer prevention across Northeast Ohio.

• Learn more about Daniel Simon, MD
• Learn more about Theodoros Teknos, MD
• Learn more about Gary Schwartz, MD
• NEW! View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Join Dr. Daniel Simon as he interviews Dr. Igho Ofotokun, Chair of the Department of Medicine at University Hospitals. Dr. Ofotokun shares his remarkable journey from Nigeria to becoming an expert in HIV research, revealing how passion and experiences shaped his career in infectious diseases. Discover the pivotal moments that guided him in the fight against not just HIV, but also the challenges posed by COVID-19.

• Learn more about Daniel Simon, MD
• Learn more about Igho Ofotokun, MD, MSc
• NEW! View our Science@UH video podcast on YouTube
• Learn more about the University Hospitals Research & Education Institute

Stanley Bazarek, MD, and Jennifer Sweet, MD, discuss the latest advances in neuromodulation, peripheral nerve surgery, and neuroengineering, highlighting the critical role of multidisciplinary collaboration between UH, Case Western Reserve University, and national research partners in translating these innovations from the lab to patient care.

• Learn more about Stanley Bazarek, MD
• Learn more about Jennifer Sweet, MD
• Learn more about the University Hospitals Research & Education Institute

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO

Varun Sundaram, MD, PhD, discusses how his experiences shaped his groundbreaking work in global heart failure research, from uncovering international differences in patient care to leading studies on GLP-1 therapies and advanced heart failure.

• Learn more about Varun Sundaram, MD, PhD
• Learn more about the University Hospitals Research & Education Institute

Follow Us on Social:

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO

Neuropsychiatrist Brian Appleby, MD, discusses prion diseases, including Creutzfeldt-Jakob disease, and the groundbreaking research and clinical trials at University Hospitals aimed at better understanding these rare but fatal neurodegenerative conditions.

• Learn more about Brian Appleby, MD
• Learn more about the University Hospitals Research & Education Institute

Follow Us on Social:

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO

Amanda Amin, MD, Janice Lyons, MD and Alberto Montero, MD, explore the evolution of breast cancer treatment. The discussion highlights how personalized care, clinical innovation and compassionate teamwork are transforming patient outcomes.

• Learn more about Amanda Amin, MD
• Learn more about Janice Lyons, MD
• Learn more about Alberto Montero, MD
• Learn more about the University Hospitals Research & Education Institute

Follow Us on Social:

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO

Guilherme Attizzani, MD, shares his inspiring journey beginning as a research fellow in intravascular imaging and rising to become a national and international leader in structural heart disease interventions.

• Learn more about Guilherme Attizzani, MD
• Learn more about the University Hospitals Research & Education Institute

Follow Us on Social:

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO

Aasef Shaikh, MD, PhD, a leading neurologist at University Hospitals discusses his journey into neurology, his groundbreaking research in neuro-ophthalmology, movement disorders, and the application of AI-driven exercise therapy for Parkinson’s disease.

• Learn more about Aasef Shaikh, MD, PhD
• Learn more about the University Hospitals Research & Education Institute

Follow Us on Social:

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO

Elie Saade, MD, MPH, Medical Director of Infection Control at University Hospitals, explains the critical role of infection prevention in healthcare, discusses strategies for reducing hospital-acquired infections, and the impact of interdisciplinary collaboration.

• Learn more about Elie Saade, MD, MPH
• Learn more about the University Hospitals Research & Education Institute

Follow Us on Social:

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO

Professor Mahmoud Ghannoum, a leading expert in medical mycology and microbiome research, shares his pioneering work on the role of fungi in the microbiome and groundbreaking research on the mycobiome’s impact on health, including its role in gut disorders, autism, and cancer.

• Learn more about the University Hospitals Research & Education Institute

Follow Us on Social:

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO

James Voos, MD, and Jacob Calcei, MD explore the impact of osteoarthritis, highlighting their team's pioneering work in regenerative therapies to revolutionize musculoskeletal care, and how they collaborate with wearable technology experts to prevent sports injuries and optimize athletic performance.

• About James Voos, MD
• About Jacob Calcei, MD
• Learn more about the University Hospitals Research & Education Institute

Follow Us on Social:

https://twitter.com/UH_RE_Institute https://www.linkedin.com/company/uh-research-education-institute https://www.facebook.com/UHResearchandEducation https://www.youtube.com/playlist?list=PL7UiR-3kRnrTioEOIl4MxHiXJr-8xqTfO