eanCast: Weekly Neurology

Moderator: Luca Sebastianelli (Vipiteno, Italy)

Guest: Arseny Sokolov (Lausanne, Switzerland)

In this episode, Luca Sebastianelli speaks with Arseny Sokolov about cognitive recovery and rehabilitation after traumatic brain injury (TBI). They discuss neuropsychological assessment, predictors of recovery, and persistent cognitive and social cognition deficits. The episode also explores personalised rehabilitation strategies, including restorative and compensatory approaches, emerging technologies, and pharmacological management, with a focus on improving everyday functioning and return to work.

Moderator: Mariusz Siemiński (Gdansk, Poland)

Guest: Barry M. Seemungal (London, UK)

In this episode, Mariusz Siemiński speaks with Barry M. Seemungal about dizziness and vertigo following mild traumatic brain injury. They discuss the clinical assessment of post-traumatic balance disorders, the identification of benign paroxysmal positional vertigo (BPPV), and key diagnostic findings that help distinguish peripheral vestibular disorders from central neurological causes and guide decisions about neuroimaging.

Moderator: Luca Sebastianelli (Vipiteno, Italy)

Guest: Geir Andre Ringstad (Oslo, Norway)

In this episode, Luca Sebastianelli speaks with Geir Andre Ringstad about the glymphatic system and its relevance to neurological practice. They discuss brain fluid transport and molecular clearance, with a focus on traumatic brain injury, sleep, diagnostic approaches, and the challenges of translating experimental findings into clinically relevant measures of individual CSF clearance.

Moderator: Mariusz Siemiński (Gdansk, Poland)

Guest: David Schreier (Bern, Switzerland)

In this episode, Mariusz Siemiński speaks with David Schreier about the relationship between sleep disorders and traumatic brain injury. They discuss sleep disorders as potential risk factors for injury, common sleep disturbances following traumatic brain injury, and the diagnostic and clinical importance of recognising sleep-wake disturbances in neurological practice.

Moderator: Luca Cuffaro (Agrigento, Italy)

Guest: Ingibjörg Jónsdóttir (Reykjavík, Iceland)

In this episode, Luca Cuffaro speaks with Ingibjörg Jónsdóttir about burnout and the neurobiology of stress-related exhaustion. They discuss the clinical features of burnout, the limitations of biological markers such as cortisol, early warning signs including impaired recovery and sleep disturbances, and the importance of recognising work-related stressors in neurological and healthcare practice.

Moderator: Lorenzo Barba (Halle Saale, Germany)

Guest: Henrik Zetterberg (Gothenburg, Sweden) and Gemma Salvadó (Barcelona, Spain)

In this episode, Lorenzo Barba speaks with Henrik Zetterberg and Gemma Salvadó about the role of biomarkers in translational neurology and monitoring therapeutic efficacy. They discuss the clinical application of fluid biomarkers, particularly plasma phosphorylated tau, key diagnostic considerations, and the emerging need for biomarkers of tau pathology, co-pathologies, and treatment response in neurological practice.

Moderator: Harald Prüß (Berlin, Germany)

Guest: Juna de Vries (Rotterdam, Netherlands)

In this episode, Harald Prüß speaks with Juna de Vries about targeted cellular therapy for anti-NMDA receptor encephalitis. They discuss key diagnostic features, current immunotherapies, and emerging approaches including CAR T-cell therapy and antibody-selective treatments, with a focus on outcome measures, prognostic assessment, early diagnosis, and their relevance to neurological practice.

Moderator: Kleopas Kleopa (Nicosia, Cyprus)

Guest: Jo Ng (London, UK)

In this episode, Kleopas Kleopa speaks with Jo Ng about gene therapy for rare neurological disorders. They discuss the clinical potential of AAV-based therapies, key diagnostic and therapeutic considerations including early diagnosis and treatment timing, and challenges related to safety, immune responses, dosing, and long-term outcomes, with a focus on translating advances into neurological practice.

Moderator: Kristian Steen Frederiksen (Copenhagen, Denmark)

Guest: Katarina Rukavina (Berlin, Germany)

In this episode, Kristian Steen Frederiksen speaks with Katarina Rukavina about guideline implementation in neurological practice. They discuss factors influencing adherence to EAN guidelines, the importance of integrating implementation from the start of guideline development, stakeholder and national society engagement, and the potential role of AI in improving access to evidence-based recommendations.

Moderator: Alessandra Fanciulli (Innsbruck, Austria)

Guest: Jalesh N. Panicker (London, UK) and Mario Habek (Zagreb, Croatia)

In this episode, Alessandra Fanciulli speaks with Jalesh N. Panicker and Mario Habek about the assessment and management of neurogenic urinary and sexual symptoms. They discuss the clinical recognition of urogenital dysfunction in neurological diseases, practical approaches to initial assessment and treatment, and the role of interdisciplinary care in improving neurological practice.

Moderator: Piergiorgio Lochner (Homburg, Germany)

Guest: Stephan Schreiber (Berlin, Germany)

In this episode, Piergiorgio Lochner speaks with Stephan Schreiber about carpal tunnel syndrome and its detection by ultrasound. They discuss key clinical and electrophysiological findings, ultrasound assessment of median nerve structure, and the recognition of anatomical or systemic red flags, highlighting the role of nerve ultrasound in diagnosis and neurological practice.

Moderator: Piergiorgio Lochner (Homburg, Germany)

Guest: Arijana Lovrečić-Huzjan (Zagreb, Croatia)

In this episode, Piergiorgio Lochner speaks with Arijana Lovrečić-Huzjan about giant cell arteritis and its neurological presentation. They discuss key clinical features, inflammatory markers, and the role of vascular ultrasound in diagnosis, with emphasis on early recognition, differential diagnosis, and timely treatment to prevent visual and cerebrovascular complications.

Moderator: Jurgita Valaikienė (Vilnius, Lithuania)

Guest: Cristina Duque (Porto, Portugal)

In this episode, Jurgita Valaikienė speaks with Cristina Duque about the multimodal assessment of carotid plaques at risk and their role in cerebrovascular disease. They discuss key imaging approaches, the Carotid Plaque-RADS classification, and the identification of high-risk plaque features to support stroke risk stratification and clinical decision-making in neurological practice.

Moderator: Jurgita Valaikienė (Vilnius, Lithuania) Guest: Theodoros Mavridis (Dublin, Ireland)

In this episode, Jurgita Valaikienė speaks with Theodoros Mavridis about reversible cerebral vasoconstriction syndrome. They discuss its clinical presentation, differential diagnosis and imaging assessment, highlighting key diagnostic challenges, important triggers, and the role of multimodal evaluation for neurological practice.

Moderator: Elisa Canu (Milan, Italy) Guest: Sophie Scott (London, United Kingdom)

In this episode, Elisa Canu speaks with Sophie Scott about the neural basis of speech and communication, focusing on the evolving role of the motor system within distributed auditory–motor networks. They discuss current evidence relevant to speech perception and production, conversational communication, and vocal behaviours, highlighting implications for the understanding and clinical assessment of communication disorders.

Moderator: Elka Stefanova (Belgrade, Serbia) Guest: Maura Panozzo Chiomento (Erfurt, Germany)

In this week’s episode, Elka Stefanova and Marua Panozzo Chiomento discuss how Parkinson’s disease affects language and communication. They explore common language impairments, their underlying cognitive and neural mechanisms, approaches to clinical assessment, and their impact on everyday communication and quality of life.

Moderator: Elka Stefanova (Belgrade, Serbia)

Guest: Stefano Francesco Cappa (Milan, Italy)

In this episode, Elka Stefanova speaks with Stefano Francesco Cappa about the relationship between language and the motor system and its implications for the evolution and neural organisation of language. They discuss evidence from cognitive neuroscience, neuroanatomy, and neurodegenerative disorders, highlighting the role of sensorimotor processes in semantic representation and acquired language dysfunction in neurological practice.

Moderator: Elisa Canu (Milan, Italy)

Guest: Cornelius Weiller (Freiburg, Germany)

In this episode, Elisa Canu speaks with Cornelius Weiller about the neural architecture underlying language, concept formation, and the brain’s interaction with the environment. They discuss the role of dorsal, ventral, and semantic pathways, convergence hubs, and their relevance for understanding language processing, cognition, and neurological disorders affecting communication and higher cortical functions.

Moderator: Gail Kinman (London, UK)

Guest: Alice Accorroni (Geneva, Switzerland)

In this episode, Alice Accorroni speaks with Gail Kinman about burnout in healthcare and the role of occupational health psychology in its prevention and management. They discuss the definition and recognition of burnout, key warning signs, and the importance of organisational factors, workplace culture, and leadership in supporting clinician wellbeing and maintaining safe neurological practice.

Moderator: Cláudia Santos Silva (Lisbon, Portugal)

Guest: Andrea Calvo (Turin, Italy)

In this episode, Cláudia Santos Silva speaks with Andrea Calvo about the genetics of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). They discuss the shared genetic basis of these disorders, key disease-associated genes, and the role of genetic testing, counselling, and result interpretation in clinical practice, highlighting how genetic discoveries are advancing precision medicine and emerging gene-targeted therapies in ALS and FTD.