Podcast

MeSsy with Christina Applegate & Jamie Lynn Sigler

Health & Fitness, Personal Journals, Society & Culture

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

Personal Journals chart
#12
Episodes
147
Releases
Weekly
Typical length
52 min
On air since
2024
Latest episode
19 hours ago

Episodes

147 episodes, newest first

  1. Jack Osbourne

    Episode 135

    Show notes

    This week, Christina and Jamie are joined by Jack Osbourne for an honest conversation about growing up in the spotlight, getting sober at 17, and being diagnosed with MS at just 26. Jack opens up about how he's navigated life's challenges, the importance of perspective, and what he's learned about resilience, fatherhood, and living with a chronic illness.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

    Blissy - Wake up with clearer skin, smoother hair, and cooler sleep. Use code MESSY for an extra 30% off at https://blissy.com/messy.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    52 min
  2. We're All Just Living This MeSsy Life

    Episode 134

    Show notes

    This week, Christina and Jamie read listener emails and discuss navigating life without a diagnosis, the challenges of parenting teenagers, learning to accept help, and the realities of getting older.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    OneSkin 0 Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod

    MyAlloy - With Alloy, your best hair isn’t behind you. Visit https://myalloy.com/ and use the code MESSY to get 20 percent off your first order. Your menopause-specialized doctor will tailor your care to your needs — plus, you get zero dollar unlimited messaging with your doctor. This code is valid on products only.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    51 min
  3. Christina Is Back (Part 2) with Dr. Marwa Kaisey

    Episode 133

    Show notes

    In part two of their conversation, Jamie and Christina are joined by Dr. Marwa Kaisey, an Associate Professor of Neurology at Cedars-Sinai in Los Angeles.

    Send us an email: https://www.messythepodcast.com/contact

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Ridge - One thing to pack, five ways to power! Get 10% Off @Ridge with code MESSY at https://www.ridge.com/messy

    NOCD - If you're struggling with OCD or unrelenting intrusive thoughts, NOCD can help. Book a free 15 minute call to get started: https://learn.nocd.com/messy

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    44 min
  4. Christina Is Back (Part 1)

    Episode 132

    Show notes

    Christina is finally back! This week, she returns to MeSsy and joins Jamie to catch up on everything that’s been going on in her life over the past six months.

    Send us an email: https://www.messythepodcast.com/contact

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    ZocDoc - Head to https://zocdoc.com/messy to get started and check that appointment off your to-do list!

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    36 min
  5. Learning to Love Every Version of Yourself with Tiffani Thiessen

    Episode 131

    Show notes

    This week, Jamie is joined by Tiffani Thiessen. They talk about growing up in the spotlight, navigating rejection, embracing aging, and learning to love every version of yourself.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Lola - Get 40% off select Lola Blankets products at https://lolablankets.com/ by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

    Jones Road - Use code MESS at https://www.jonesroadbeauty.com/ to get a Free Gift with your first purchase! #JonesRoadBeauty #ad

    K18 - Shop at Sephora or get 10% off your first purchase at https://k18hair.com/ with code [MESSY]

    Blissy - Wake up with clearer skin, smoother hair, and cooler sleep. Use code MESSY for an extra 30% off at blissy.com/MESSY.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    54 min
  6. What If You’re Not Stuck, You’re Just in Between? with Emmanuelle Chriqui

    Episode 130

    Show notes

    This week, Jamie is joined by her friend, actress Emmanuelle Chriqui. They talk about grief, the friendships that carry us through hard times, getting older, learning to separate your self-worth from your career, and more.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    58 min
  7. I Don’t Have a Lot of Fight in Me Right Now

    Episode 129

    Show notes

    This week, Jamie reads listener emails and discusses parenting with MS, learning to embrace mobility aids, and navigating unsolicited advice and comparisons.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at https://mudwtr.com/MESSY! #mudwtrpod

    Alloy -With Alloy, your best hair isn’t behind you. Visit https://myalloy.com/ and use the code MESSY to get 20 percent off your first order. Your menopause-specialized doctor will tailor your care to your needs — plus, you get zero dollar unlimited messaging with your doctor. This code is valid on products only.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    31 min
  8. How to Live With What You Can’t Control with Ana Rodriguez Bonus

    Show notes

    In the final episode of Living With It, Jamie sits down with her therapist, Ana Rodriguez, to talk about what it really means to heal when life doesn’t go according to plan. They explore grief, resilience, uncertainty, and the ways we avoid our feelings by trying to fix them or find meaning too quickly.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    59 min
  9. The Hardest Fight Is Learning to Rest with Alberto Crane

    Episode 128

    Show notes

    This week, Jamie sits down with jiu-jitsu champion and former UFC fighter Alberto Crane to talk about how his MS diagnosis forced him to redefine what it means to be strong. Alberto opens up about learning to slow down, embrace rest, and why sometimes being a fighter means knowing when not to push through.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    OneSkin - Get 15% off OneSkin with the code MESSYat https://www.oneskin.co/MESSY #oneskinpod

    Zoc Doc - Ready to be seen? Check that appointment off your to-do list with Zocdoc https://zocdoc.com/ messy #sponsored

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    41 min
  10. Stop Apologizing for Wanting More with Heather Dubrow Bonus

    Show notes

    This week on Living With It, Jamie sits down with Heather Dubrow for an honest conversation about embracing life’s pivots, protecting your peace, and giving yourself permission to want more.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    55 min
  11. There Is Beauty Within All of This Pain with Lindsey Kraft

    Episode 127

    Show notes

    This week on MeSsy, Jamie sits down with her longtime friend, actress, writer, and musician Lindsey Kraft. They talk about growing up together, navigating rejection and self-doubt, and Lindsey’s unexpected journey from acting to writing her own one-woman musical.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Take the MeSsy Survey - Please help out the show by taking our survey at https://messythepodcast.com/survey

    Novartis in neuroscience

    Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Lola - Get 40% off select Lola Blankets products at https://lolablankets.com/ by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

    K18 - Shop at Sephora or get 10% off your first purchase at https://k18hair.com/with code MESSY. That’s code MESSY at http://k18hair.com/

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    54 min
  12. Falling Apart to Come Back Together with Ryan Weiss Bonus

    Show notes

    This week on Living With It, Jamie sits down with her friend, Ryan Weiss. They talk about letting go of control, sitting with difficult emotions, knowing when it’s time to do things differently, and learning to trust what’s on the other side when life doesn’t look the way you thought it would.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    47 min
  13. Thank God I’m So Neurotic with Cat Cohen

    Episode 126

    Show notes

    This week on MeSsy, Jamie sits down with comedian, actor, and singer Cat Cohen. Cat opens up about having a stroke at 31, navigating health anxiety in the aftermath, and turning one of the scariest experiences of her life into her most fulfilling creative work yet.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Jones Road - Use code MESS at https://jonesroadbeauty.com/ to get a Free Gift with your first purchase! #JonesRoadBeauty #ad

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    48 min
  14. We Fight For Joy with Kelsey Chittick Bonus

    Show notes

    This week on Living With It, Jamie sits down with Kelsey Chittick to talk about losing her husband suddenly, raising two children through grief, and learning to build a life she never expected. They discuss finding humor in the darkest moments, letting go of the life you thought you’d have, the power of community, and how to choose joy.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    54 min
  15. There’s No Place Like Home with Annie Meyers-Shyer

    Episode 125

    Show notes

    This week, Jamie is joined by her longtime friend Annie Meyers-Shyer, the creator behind This Oak House. They talk about Annie’s unexpected second act, finding a new passion and career at 45, and why it’s never too late to bet on yourself. Annie also shares how she creates a home that feels like an exhale, the small ways our spaces can support us through difficult seasons, and how her home carried her through grief.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

    ZBiotics - Go to https://zbiotics.com/messy and use MESSY at checkout for 15% off any first time orders of ZBiotics probiotics.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    53 min
  16. The Power of Radical Acceptance with Jim Curtis Bonus

    Show notes

    This week on Living With It, Jamie sits down with Jim Curtis, a transformational coach, author, and wellness leader. They discuss how to radically accept the life you have without giving up hope for the life you want, the stories we build around our suffering, and learning to see your body as an ally instead of the enemy. Plus, Jim shares how releasing old beliefs and changing the way we speak to ourselves can open us up to new possibilities.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    54 min
  17. Jamie's Son Beau

    Episode 124

    Show notes

    This week, Jamie sits down with a very special guest: her 13-year-old son, Beau. They have an honest conversation about what it’s been like growing up with a mom who has MS, how Jamie’s strength has shaped him, and what he wants other kids and parents living with chronic illness to know.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    MudWtr -Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at https://mudwtr.com/messy! #mudwtrpod

    OneSkin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod

    MyAlloy -Try the original estrogen-powered M4 skincare from Alloy. Visit https://myalloy.com/ and use code MESSYfor $20 off your first order!

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    43 min
  18. Accept, Adapt, Appreciate with Odette Annable Bonus

    Show notes

    This week on Living With It, Jamie sits down with her friend Odette Annable. They discuss parenting a neurodivergent child, trusting your instincts, advocating for your family, and learning to let go of the need to have all the answers.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    54 min
  19. The Courage to Slow Down

    Episode 123

    Show notes

    This week on MeSsy, Jamie opens up about reaching her limit and learning to make rest part of healing. She also reads listener emails about fighting to be heard by doctors, learning to accept help, and the power of knowing you're not alone.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Lola Blankets - Get 40% off select Lola Blankets products at Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

    ZocDoc - Head to https://https://zocdoc.com/MESSYto get started and check that appointment off your to-do list!

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    53 min
  20. Finding Stillness When Life Won’t Slow Down with Bob Roth Bonus

    Show notes

    This week on Living With It, Jamie sits down with Bob Roth, a leading Transcendental Meditation teacher and CEO of the David Lynch Foundation. They discuss what stress does to the body, how meditation can help calm the nervous system, and how finding stillness can help us navigate uncertainty, illness, and everyday life.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

    1 hr