Health & Veritas: Yale's Healthcare and Health Policy Podcast

Howie and Harlan are joined by Yale School of Medicine sleep specialist Christine Won to discuss what makes for a good night's sleep and why sleep trackers and supplements may do more harm than good. Amid renewed discussion of "Medicare for All," Howie explains why Medicare falls short of universal coverage for current beneficiaries and proposes reforms; Harlan examines common misconceptions about longevity and what it takes to live a longer, healthier life.

Show notes:

The Cost of Being on Medicare

Medicare.gov: 2026 Medicare costs (PDF)

Library of Congress: "Finding Medicare Fee-for-Service (FFS) Payment System Rules: Schedules and Resources"

Library of Congress: "Medicare Part D Prescription Drug Benefit"

Medicare.gov: "Get Medigap Basics"

"MedPAC Findings Versus The Insurance Industry: Is MA Paid More Than Traditional Medicare?"

MedPAC: "The Medicare Advantage program: Status report"

Social Security and Medicare Boards of Trustees: "A Summary of the 2026 Annual Reports"

Better Sleep

"Tired of not sleeping? These tips might help you rest better"

Emmanuel Mignot, MD, PhD

Meir Kryger, MD, FRCPC

"What Is a Siesta?"

Circadian Rhythm: What It Is, How It Works & What Affects It

"Light exposure during sleep impairs cardiometabolic function"

Melatonin: What It Is, What It Does & How It Works

Short Sleeper Syndrome: What It Is, Symptoms & Treatment

"Long Sleepers"

Andrew Krystal, MD

Sleep apnea—Symptoms and causes

Christine Won: "Sex differences in obstructive sleep apnea phenotypes, the multi-ethnic study of atherosclerosis"

Hypersomnia: What It Is, Causes, Symptoms & Treatment

Christine Won: "Sleep in Women Across the Life Span"

"Cannabis for Sleep"

"Recent and Cumulative Cannabis Use and Sleep in Middle-Aged Adults"

"Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity"

"Mitochondrial origins of the pressure to sleep"

Longevity Misconceptions

"6 Things Longevity Experts Wish People Would Stop Saying"

"Heritability of intrinsic human life span is about 50% when confounding factors are addressed"

"Association of Later-Life Weight Changes With Survival to Ages 90, 95, and 100: The Women's Health Initiative"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Yale School of Public Health senior fellow Ashwin Vasan to discuss the ambitious agenda he pursued as New York City health commissioner: helping New Yorkers live longer, transforming mental healthcare, and rethinking what government can do to make people healthier. Howie examines the blood clots suffered by Philadelphia Eagles quarterback Jalen Hurts and the questions they raise about player safety; Harlan discusses the financial pressures that put healthcare out of reach for many Americans.

Show notes:

Blood Clots and the NFL

"NFL Network: Eagles QB Jalen Hurts likely out for rest of 2026 season due to blood clots"

Pulmonary embolism: symptoms and causes

"Venous Thromboembolism Within Professional American Sport Leagues"

CDC: Data and Statistics on Venous Thromboembolism

"No apparent association between mRNA COVID-19 vaccination and venous thromboembolism"

"NFL commissioner says protocols were 'incredibly good' and welcomes investigation after Jalen Hurts injury"

Ashwin Vasan

"Mayor Mamdani Appoints Dr. Dave A. Chokshi to the NYC Board of Health"

Omicron Variant: Symptoms and Treatment

Legionnaires' disease: symptoms and causes

Ashwin Vasan: "Balancing Personal Choice and Societal Factors in Health"

Peptides: Types, Health Benefits, and Uses

NYC Health: Healthy New York City: Goals for 2030

What Is Cardiovascular Disease?

NYC Health: Public Health Corps

Mary Bassett

Fountain House

Man in the Mirror: Hope, Struggle, and Belonging in an American City

"Who is Jordan Neely, the man killed in NYC subway chokehold death?"

"Community Mental Health Act of 1963: Passage, Repeal, and Aftermath"

Mountains Beyond Mountains

"World Health Organization and UNAIDS unveil plan to get 3 million AIDS patients on treatment by 2005"

Commonweal Ventures

Financial Insecurity in America

"Many Americans Are Struggling to Afford Basic Necessities"

Pew Research Center: "Americans and AI 2026: Chatbots, Smart Devices and Views on Impact"

"ICER, West Health Release New Report Indicating that Median Prices of Newly Launched Drugs Continue to Exceed $250,000"

"Social Security Trustees Report Warns of 22% Benefit Cut In 2032"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan discuss new research into the biological mechanisms behind long COVID and other post-infectious syndromes, how the FDA can ensure the safety of AI-powered medical tools, and why prior authorization can discourage necessary care even when treatments are ultimately approved. They also examine an early flu season, the changing calculus of COVID vaccination, and the continuing surge in measles cases.

Howie and Harlan are joined by Yale School of Medicine cardiologist Eric Velazquez to discuss how advances in treatment have transformed cardiovascular medicine and how technology could make care more accessible and equitable. Howie reports on a possible case of plague in Russia; Harlan reflects on how AI is changing the relationship between doctors and patients—and what that means for medical education.

Show notes:

Plague

"Pneumonic plague: WHO says it wants more details from Russia in death of worker at research lab"

"Dozens quarantined after researcher at Russian plague laboratory dies of 'unknown' infection"

"U.S. Seeks Information From Russia on Possible Plague Death"

"Rumors Are Swirling of a Plague Outbreak in Russia. Here's What We Know."

"What to know about pneumonic plague

"World Health Assembly adopts historic Pandemic Agreement to make the world more equitable and safer from future pandemics"

CDC: International Health Regulations

WHO: Biological weapons

Eric Velazquez

Yale School of Medicine: Cardiovascular Medicine

Yale Cardiovascular Research Center (YCVRC)

Center for Outcomes Research & Evaluation (CORE)

Interventional Cardiology

Myocardial Infarction (MI)

Stent

Statins

Beta-Blockers

Atrial fibrillation

Structural Heart Disease

Heartbeat Health

"What Is an Ambulatory Center? How It Differs From a Hospital"

Expertise and AI

Harlan Krumholz: "Beyond Information Asymmetry in Medicine: The Changing Nature of Medical Authority and Expertise"

"Why Do London Taxi Drivers Have Larger Hippocampuses?"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by journalist Gary Wolf, author of the new book The Quantified Self: Learning to Observe, and patient researcher Sara Riggare, who has spent years studying her own experience with Parkinson's disease to better understand and manage her health. They discuss how systematic self-observation can help people ask better questions and learn more about their own health. Howie examines Sweden's use of AI as a second reader of screening mammograms; Harlan asks whether AI will streamline healthcare billing or fuel an arms race between providers and insurers.

Show notes:

AI Radiologists

"Health system will use AI instead of radiologists for breast imaging 2nd reads"

"Lunit Expands AI-Powered Breast Cancer Screening Across the Stockholm Region"

"Artificial intelligence for breast cancer detection in screening mammography in Sweden: a prospective, population-based, paired-reader, non-inferiority study"

Joann G. Elmore, MD, MPH

The Quantified Self

Quantified Self: Self-Knowledge Through Numbers

Gary Wolf: The Quantified Self: Learning to Observe

Quantified Self: Personal Science Research Group

"N-of-1 Trial Design: Single-Patient Crossover Methodology"

What is Parkinson's?

Sara Riggare: "The Red Dot and the Blue Dots: My ISDM 2026 Keynote"

Sara Riggare: "Precision Medicine in Parkinson's Disease—Exploring Patient-Initiated Self-Tracking"

Sara Riggare: "The Burden of Tracking"

TED Talk by Gary Wolf: "The Quantified Self"

Gary Wolf: "The Data-Driven Life"

"What Is Biohacking and Is It Safe?"

Gary Wolf: "A Conceptual Framework for Personal Science"

AI Billing

"What Is Revenue Cycle Management (RCM)?"

"Agentic AI and the race to a touchless revenue cycle"

"Analysis examines AI in hospital billing as spike in complex patients adds nearly $1 billion in extra costs"

"Hospital Coding Intensity Analysis"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by pediatric cardiologist Emily Bucholz to discuss her work treating fetal heart abnormalities across a multistate region and the challenges of bringing specialized pediatric care to patients far from major medical centers. For Suicide Prevention Month, Howie examines evidence that restricting access to lethal means can prevent suicide; Harlan pays tribute to the late Yale political scientist Theodore Marmor and remembers a moment when Marmor's mentorship changed his professional path.

Show notes:

Preventing Suicide

Suicide Prevention Month

CDC: Leading Causes of Death

"Declining gun homicides, record gun suicides in 2024"

"Banning pesticides saves lives from suicide"

Strong Star Training Initiative: Caring Contacts

Emily Bucholz

Children's Hospital Colorado:Fetal Cardiology Program

"Fetal Cardiology: What is it? Why is it important?"

Children's Hospital Association: About Children's Hospitals

"Telemedicine: Definition, uses, benefits, and more"

Children's Hospital Colorado

"Differences Between Primary, Secondary, Tertiary, and Quaternary Care"

CDC: About Congenital Heart Defects

Mayo Clinic: Electrocardiogram

Cleveland Clinic: Chambers of the Heart

NIH: Medical Scientist Training Program

Yale Center for Outcomes Research & Evaluation (CORE)

"Ensuring Readiness for Practice: Advancing Competency-Based Subspecialty Training"

The Children's Heart Foundation

Remembering a Mentor

Harlan Krumholz: "The Return on Mentorship"

Yale School of Management: "Remembering Professor Emeritus Theodore Marmor, 1939–2026"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Omar Lateef, CEO of Chicago's Rush University System for Health, to discuss balancing the financial pressures facing hospitals with commitments to patient care, community health, and research—and why healthcare leaders will need to rethink traditional models of care. Howie examines how proposed changes to student and exchange visitor visas could affect international researchers and physicians; Harlan discusses proposed changes to Medicare payment for remote patient monitoring.

Show notes:

Visa Rules

"Judge blocks Trump administration plans to limit visa length for grad students, postdocs"

NAFSA: Duration of Status Rule

"AAMC Statement on Duration of Status Final Rule"

"What does the new duration of status rule mean for international students and workers?"

Memorandum and Order on Motion for Preliminary Injunction

Omar Lateef

Rush University Medical Center

Stat Status List 2025: Omar Lateef

"Modern Healthcare Again Lists Rush CEO Among Most Influential"

Rush Remains Among Nation's Best in Vizient Quality Rankings"

"Corporate Finance Institute: Debt Covenants

"Bond Covenants Demystified: What You Need to Know"

"Health Equity as a System Strategy: The Rush University Medical Center Framework"

"A Community Anchor for Health Equity"

Fillmore Center Laundry Linen

"Rush Signs on as First Partner for Local Laundry Service"

"Key Facts About Hospitals": Profit Margins

"Despite sectorwide financial recovery, not all are hospitals are finding their footing"

"Hospital Margins Rebounded in 2023, But Rural Hospitals and Those With High Medicaid Shares Were Struggling More Than Others"

Payments for Remote Monitoring

Remote Patient Monitoring

"Billing for Remote Patient Monitoring in Medicare"

"States are betting millions on remote monitoring. Providers, tech groups say proposed Medicare policy could undercut it"

"CMS Proposes Transformational Medicare Reforms to Expand Accountable Care, Modernize Physician Payment, and Shift from Sick Care to Healthcare"

CMS: "Medicare and Medicaid Programs; CY 2027 Payment Policies Under the Physician Fee Schedule and Other Changes to Part B Payment and Coverage Policies; Medicare Shared Savings Program Requirements; and Medicare Prescription Drug Inflation Rebate Program"

"Telemonitoring in Patients with Heart Failure"

CMS: ACCESS (Advancing Chronic Care with Effective, Scalable Solutions) Model

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by cardiologist Aakriti Gupta to discuss advances in minimally invasive heart valve treatment, her work to expand access to cardiovascular care through technology and AI, and a major clinical trial on aortic valve replacement. Howie examines claims that immigration is driving the surge in measles cases; Harlan discusses disappointing trial results for two drugs aimed at preventing cardiovascular disease.

Show notes:

September 11

9/11 Memorial & Museum: Marking the 25th Anniversary

Measles

CDC: Measles Cases and Outbreaks"

"No evidence linking illegal immigration to measles outbreak, despite Byron Donalds' comment".

"Kindergarten Routine Vaccination Rates Continue to Decline"

"'Real-life consequences': Pennsylvania Gov. Shapiro, RFK Jr. spar over measles-associated deaths"

"Two unvaccinated people die of measles in Pennsylvania"

Aakriti Gupta

Center for Outcomes Research & Evaluation (CORE)

Structural Heart Disease

Structural Heart Disease and Interventional Cardiology

Heart Valve Disease

Open-Heart Surgery

Transcatheter aortic valve replacement (TAVR)"

"Gender Bias in Choosing Cardiology, Training and Early Career Development"

Rajendra Makkar

Tia Health

Jeff Wessler

Heartbeat Health

Echocardiogram

https://www.icardio.ai/

AllHeart

BELIEVERS trial

Failed Drug Trials

"Novo Nordisk stops two cardiovascular studies aimed at lowering inflammation"

"Ionis partner Novartis announces Lp(a)HORIZON Phase 3 topline results for pelacarsen in patients with elevated Lp(a) and established cardiovascular disease"

Lipoprotein(a)

GLP-1 Agonists

Howie and Harlan discuss health headlines including the ongoing cyclosporiasis outbreak; a recent FDA decision allowing pharmacies to compound certain peptides; and a concerning report from Medicare trustees on the program's financial future. They also dive into the health habits they're changing this year and a new feature from ChatGPT allowing users to connect medical records and health data to the platform.

Watch a video edition of this episode.

Show Notes:

Healthy Habits

Health & Veritas: Ezekiel Emanuel

"What's Erythritol? And Is It Bad for You?"

NIH: Aging and Alcohol

"Low-plastic diet and urinary levels of plastic-associated phthalates and bisphenols: the randomized controlled PERTH Trial"

Health & Veritas: Eric Topol

Cyclosporiasis Outbreak

CDC: Surveillance of Cyclosporiasis

FDA: Investigation of 9-State Outbreak of Cyclospora Illnesses: Iceberg Lettuce (July 2026)

"Cyclospora Outbreak Linked to Iceberg Lettuce in 9 States"

National Foundation for Infectious Diseases: Norovirus

FDA: Cyclospora

CDC: Clinical Overview of Cyclosporiasis

CDC: About FoodNet

CDC: About PulseNet

FDA: FSMA Final Rule on Requirements for Additional Traceability Records for Certain Foods

Peptides and the FDA

Health & Veritas: Trust, Truth, and Moral Distress

"Peptides: What they are, potential benefits, and safety concerns"

"FDA committee votes to make peptides more widely available"

LinkedIn: Ezekiel Emanuel

The Future of Medicare

OASDI: Trustees Report Summary

U.S. Department of the Treasury: Social Security and Medicare Trustees Reports

H.R.1: An act to provide for reconciliation pursuant to title II of H. Con. Res. 14.

IRS: Inflation Reduction Act of 2022

ChatGPT Ventures into Health

"Launching Health in ChatGPT"

"OpenAI makes Health in ChatGPT widely available, moving deeper into consumer health"

"ChatGPT Led to a Man's Near-Fatal Health Crisis, Lawsuit Claims"

LinkedIn: David Rhew

A Record Measles Season

Health & Veritas: Measles Outbreaks, Preventative Cardiology, and Other News

CDC: Measles Cases and Outbreaks

"Measles Cases in the U.S. Are at a 35-Year High"

"What ProPublica Found in the Genetic Code of America's Measles Outbreaks"

Pan American Health Organization

Senator Bill Cassidy

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Melanie Matheu, co-founder and chief scientific officer of Lyric Bio, who also shares evidence-based health and science information on TikTok as LaughterinLight PhD. They discuss developing new antibody therapies, building biotech companies, and communicating complex science to the public. Harlan warns that AI could drive up healthcare costs unless payment models change; Howie highlights encouraging declines in traffic deaths while noting the growing risks associated with e-bikes and e-scooters.

Show notes:

AI and Healthcare Costs

"What Is Fee for Service in Healthcare and How It Works"

"Payment for Clinical AI"

"CMS floats new Medicare payment category for AI diagnostic software: 6 notes"

Melanie Matheu

LaughterinLight PhD on TikTok

Lyric Bio

Hyper-IgM (HIgM) Syndromes

Polyclonal Antibodies (PAbs)

Autoimmune Diseases

Kawasaki disease

NIH: R01 research grants

Prellis Biologics

Cyclosporiasis

"FDA says false-positive lettuce test doesn't change Taylor Farms cyclospora probe"

WHO: Ebola virus disease outbreak in the Democratic Republic of the Congo

Dr. Zachary Rubin

From Bench to Bedside podcast

Zachary Rubin: All About Allergies: How to Live Well with Asthma, Food Allergies, Hay Fever and More

Road Safety

"The '100 Deadliest Days' Have Begun"

WHO: "Road deaths fall by 21% globally but stronger action is needed to save lives"

NHTSA: "Crash-Stats: Early Estimate of Motor Vehicle Traffic Fatalities and Fatality Rate in 2025"

Consumer Product Safety Commission: "Micromobility Products-Related Deaths Injuries and Hazard Patterns 2017-2024"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Shivan Mehta, associate chief innovation officer at the University of Pennsylvania Health System, to discuss how healthcare organizations can use behavioral science to remove barriers that keep patients from getting recommended care. Harlan warns that ill-defined rules governing scientific collaboration with China could chill medical research; Howie revisits the discovery of Legionnaires' disease 50 years ago as New York confronts a new outbreak.

Show notes:

Restrictions on Collaboration

National Science Foundation "Prohibition on Collaborations with Restricted Entities"

"Fact of the Week: China Has Surpassed the US in the Number of Drug Clinical Trials, With 1,100 More Trials Listed"

Texas Executive Order GA-48 Governor Greg Abbott's executive order restricting travel to China and other countries.

Shivan Mehta

Shivan Mehta: "Texting in Health Care—Preserving Impact and Managing Influx"

Kevin Volpp, MD, PhD

"Randomized controlled trials – The what, when, how and why"

CDC: Screening for Colorectal Cancer

Cleveland Clinic: What is a Gastroenterologist?

Cologuard Plus Colon Cancer Screening Test

Mayo Clinic: Colonoscopy

"What to know about the new blood-based test for colorectal cancer"

Mayo Clinic: Fecal immunochemical test

Mayo Clinic: Colon polyps

Cleveland Clinic: Fecal Occult Blood Test

"Non-invasive blood and stool CRC screening tests: Available modalities and their clinical application"

"Race/Ethnicity and Adoption of a Population Health Management Approach to Colorectal Cancer Screening in a Community-Based Healthcare System"

Integrated Delivery System

Corinne M. Rhodes, MD, MPH

Legionnaires' Disease

CDC: Legionnaires' Disease

"New York Is Having a Legionnaires' Outbreak. Here's What to Know."

"Mayor Mamdani Takes Aggressive Action to Address Upper East Side Legionnaires' Disease Community Cluster"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Kate Heilpern, president of Yale New Haven Hospital, to discuss the hospital's 200-year history, the financial pressures facing health systems, and how Yale New Haven is balancing innovation with its mission to serve the local community. Harlan examines the growing burden of U.S. healthcare costs; Howie highlights encouraging trends in infant mortality, life expectancy, overdose deaths, and cancer survival.

Show notes:

Healthcare Costs

"National Health Expenditure Projections, 2025–34: Strong Utilization Growth Initially, Legislative Impacts Later"

"KFF Health Tracking Poll: Health Care Costs, Expiring ACA Tax Credits, and the 2026 Midterms"

"Americans See Health Care Costs, Deficit, Inflation as Big Problems Facing the Nation"

"How Much and Why ACA Marketplace Premiums Are Going Up in 2027"

"U.S. Health Care from a Global Perspective, 2026"

"The Cost of Health Insurance for a Family Jumps to $27,000"

Zack Cooper

"FDA approves Trutakna for IgA nephropathy"

Kate Heilpern

Yale New Haven Hospital: Vision, Mission, and Values

Yale New Haven Hospital: History and Heritage

"A Bicentennial Milestone: Yale New Haven Hospital Reflects on 200 Years of Care"

Megan L. Ranney

Azita Emami

CDC: Social Determinants of Health

Health & Veritas Episode 188: "Kate Heilpern: Jumping into the Deep End"

American Hospital Association: "Costs of Caring"

Adams Neurosciences Center

Positive Trends in Mortality

CDC: Infant Mortality Quarterly Provisional Estimates

"Life Expectancy in U.S. Hit Record High of 79 Years in 2024, CDC Says"

CDC: "Provisional Data: U.S. Death Rate Fell to a Record Low in 2025"

CDC: Provisional Drug Overdose Data

CDC: Maternal Mortality Rates in the United States, 2024

"American Cancer Society Releases Latest Cancer Statistics"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

In this special episode, Howie and Harlan revisit their conversation with trauma surgeon Selwyn Rogers, whose book Healing the Gun Violence Epidemic: Ending Violence, Rebuilding Communities, and a Trauma Surgeon's Vision for Restoring Hope was published on July 7.

Show notes:

Selwyn Rogers: Healing the Gun Violence Epidemic: Ending Violence, Rebuilding Communities, and a Trauma Surgeon's Vision for Restoring Hope

Albert Ko

"Selwyn Rogers named associate editor of prestigious New England Journal of Medicine"

Selwyn Rogers: "Hope—Beyond Firearm Trauma"

Selwyn Rogers: "Structural Racism and Firearm Injury: Operationalizing Health Equity in Trauma Care"

Brain Death: What it is, Stages & Criteria

New York Times Live Updates: Supreme Court Birthright Citizenship Case

Annual Gun Violence Data 2023

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Jessica Federer, managing director of the Women's Health Fund and a member of the Yale Institutional Review Board, to discuss how investors can help address the dearth of research on medical problems facing women and why she's optimistic about the future of women's health. Harlan explains how caps on indirect costs affect institutional staffing and research agendas; Howie reports on a lawsuit filed by 26 states against the Trump administration over bureaucratic hurdles to accessing Medicaid coverage.

Show notes:

Indirect research costs

Yale Research Support: Facilities and Administrative (F&A) Costs

Yale University: Colleges and Universities Rate Agreement

"NIH Indirect Costs Policy for Research Grants: Recent Developments"

Jessica Federer

Yale School of Public Health

Megan L. Ranney, Dean of the Yale School of Public Health

Agency for Healthcare Research and Quality

The Women's Health Fund

Yale School of Medicine: Basmah Safdar

Health & Veritas: Basmah Safdar

Women's Health Research at Yale

"Women's Health Research at Yale and SWHR's Symposium Highlights the Power of Collaboration to Advance Women's Health Research"

"CARE for women: Investing in care delivery to improve women's lives and livelihoods"

LinkedIn: Jessica J. Federer

Health & Veritas: Live at the Yale Innovation Summit 2026

"What Is a General Partner in Venture Capital (VC)?"

"April Koh (Co-Founder & CEO, Spring Health) Featured on Cover of TIME"

"Closing the Gap: How Yale Is Advancing Women's Health Research"

Medicaid work requirement

"States Sue CMS Over Medicaid Work Requirements Rule, Citing Departure from Earlier Guidance on Medical Frailty"

Massachusetts v. Oz [pp. 208-231]

Health & Veritas: Ryan Schwarz

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Yale School of Public Health biostatistician Bhramar Mukherjee to discuss how statisticians help researchers turn observations into evidence. Harlan examines a new study linking updated COVID vaccination to lower cardiovascular risk and explains why a headline-grabbing result may not settle the question; Howie discusses new Medicaid work requirements and the danger that administrative hurdles could cost vulnerable patients their coverage.

Show notes:

The COVID-19 Vaccine and Cardiovascular Health

"2024-2025 COVID-19 Vaccine and Major Adverse Cardiovascular Events Among US Veterans"

"Target Trial Emulation—A Unifying Approach for Causal Inference From Observational Data | Research, Methods, Statistics"

"Risk Reduction: Absolute vs. Relative Explained"

Bhramar Mukherjee

"Ten Core Concepts for Ensuring Data Equity in Public Health"

Bhramar Mukherjee: "Privacy-enhancing sequential learning under heterogeneous selection bias in multi-site electronic health records data"

Michigan Genomics Initiative

NIH: All of Us Research Program

Megan Ranney, Dean of the Yale School of Public Health

Big Data Summer Immersion at Yale

"The big data paradox and significance"

'What Is Variance in Statistics? Definition, Formula, and Example"

Medicaid work requirements

Center for Health Care Strategies: Summary of Federal Medicaid Work Requirements

"CMS Requires More Restrictive Definition of Medical Frailty in New Medicaid Work

Requirements Rule"

Cleveland Clinic: Frailty

"Coverage losses, substantial confusion in Arkansas following implementation of Medicaid work requirements"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Ingrid Katz, director of the Yale Institute for Global Health, to discuss why HIV continues to spread despite the existence of cheap and effective treatment, what AIDS activism can teach us about tackling chronic diseases like hypertension, and what outbreaks like Ebola reveal about the consequences of fragile health systems. Harlan reports on a breach of UK Biobank data and what it means for the future of open science; Howie highlights two recent papers illustrating the importance of vitamin C and the danger of treating it as a cure-all.

Show notes:

The UK Biobank Data Breach

UK Biobank

NIH: All of Us Research Program

"UK Biobank health data listed for sale in China, government confirms"

"UK Biobank: Confidential patient health details still online three months after leaks, BMJ finds"

Ingrid Katz

HIV

PEPFAR

The Global Fund to Fight AIDS, Tuberculosis and Malaria

Differentiated Service Delivery

Hypertension

"Prevalence, Awareness, and Treatment of Hypertension in 37 African Countries: Trends From 2003 to 2022"

Noncommunicable Diseases (NCDs)

Treatment Action Campaign

"Health & Veritas Episode 224: Nicholas Christakis: The Science of Human Connection"

CDC: Ebola Outbreak: Current Situation

South African president Thabo Mbeki

"More than Two Decades Since the Abuja Declaration: A Way Forward for Ending AIDS as a Public Health Threat by 2030"

Vitamin C

Linus Pauling

"High-Dose Intravenous Vitamin C and Mortality and Organ Dysfunction in Severe Burn Injury: The VICTORY Randomized Clinical Trial"

"High-Dose Vitamin C in Burns: Time to Stop"

"A 7-Year-Old Girl with Limping and Leg Pain"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan discuss healthcare headlines including proposed changes to federal research funding, an outbreak of New World screwworm in Texas cattle, and the debate over free expression after researchers were removed from the American Diabetes Association meeting for distributing an editorial critical of federal science policies. They also examine the future of generic GLP-1 drugs, a new Medicare model for heart failure care, and a court ruling with implications for international physicians practicing in the United States.

Show notes:

Research Grants

NIH: NOT-OD-25-132: Supporting Fairness and Originality in NIH Research Applications

Akiko Iwasaki

Health & Veritas Episode 192: Akiko Iwasaki: What Have We Learned About Long COVID?

Stuart Buck

"White House proposes new rules giving political appointees final approval on research grants"

U.S. Constitution: Article II

Skinny Labeling and the Supreme Court

"Supreme Court Upholds Preventive Services Requirement Under ACA"

"Supreme Court Rejects Colorado Law Banning 'Conversion Therapy' for L.G.B.T.Q. Minors"

Hikma Pharmaceuticals USA Inc. v. Amarin Pharma, Inc. (24-889)

"Hikma v. Amarin: Supreme Court Weighs Future of 'Skinny Labeling'"

Value-Based Care

CMS: Value-Based Care

CMS: Hospital Readmission Reduction

New World Screwworm

CDC: New World Screwworm

USDA: New World Screwworm Economic Impact Report

USDA: Eradicating New World Screwworm with Sterile Insect Technique

American Diabetes Association Meeting

"Join the ADA in New Orleans for the 2026 Scientific Sessions"

NIH Director Jay Bhattacharya

Diabetes Care: "Misguided Brushes of a Pen Continue to Dismantle and Destroy Biomedical Research in the United States: We Can No Longer Afford Complacency and Fear. We Must All Act Now!"

"Diabetes researchers ousted from conference after criticizing Trump"

H-1B Visas

Presidential Proclamation on Restriction on Entry of Certain Nonimmigrant Workers

"Federal judge blocks Trump's $100,000 H-1B visa fee"

"Health Care Professionals Sponsored for H-1B Visas in the US"

Exchange Visitors and the J-1 Classification

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Mark Siegel, director of Yale's internal medicine residency program, to discuss his approach to mentoring young physicians and building a medical community grounded in purpose and compassion. Harlan examines a breakthrough targeted therapy that could reshape the treatment of pancreatic cancer and other hard-to-treat cancers; Howie tracks the Ebola outbreak in the Democratic Republic of the Congo and argues that policy decisions are hampering the global response.

Show notes:

A Cancer Breakthrough

Pancreatic cancer: Symptoms and causes

"Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer"

"Multi-Selective RAS(ON) Inhibitor Nearly Doubles Survival Time in People With Metastatic Pancreatic Cancer"

"KRAS mutation: from undruggable to druggable in cancer"

Mark Siegel

Mark Siegel: Program Director Notes

Mark Siegel on Substack

Academic medicine

Signaling system

Mark Siegel: "What I've Learned in 63 Years"

Yale School of Medicine: Residency & Fellowship Programs

Mark Siegel: "A Sudden Loss Of Vision"

Health & Veritas Episode 224: Nicholas Christakis: The Science of Human Connection

Ebola

WHO: Bundibugyo virus disease outbreak, Democratic Republic of the Congo

WHO: Ebola, The Democratic Republic of the Congo, 2026

WHO: Alert and Response

"'We are catching up'—WHO chief on DR Congo's Ebola fight"

"Uganda Closes Border With Congo as Ebola Fears Rise"

"Kenyan Court Deals New Blow to Plans for U.S. Ebola Unit"

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie is joined by guest host Megan Ranney, dean of the the Yale School of Public Health, for a live episode recorded at the Yale Innovation Summit, featuring conversations with five innovators at the intersection of healthcare, public health, and entrepreneurship.

Jaya Dadwal, a recent graduate of the School of Public Health and founder of forEVA Health, focused on raising healthcare standards for the female body

Monique Rainford, a Yale School of Medicine ob-gyn and founder of Enrich Health, focused on addressing disparities in maternal health

Kimberley Steele, a bariatric surgeon and program director at the federal Advanced Research Projects Agency for Health (ARPA-H)

Yusuf Ransome, a faculty member at the School of Public Health and founder of Soul Health, a faith tech solution focused on addressing the mental wellbeing of the "missing middle"

Janani Ramaswamy, head of IP and licensing services at Yale Ventures

Show notes:

The Yale Innovation Summit

Yale Innovation Summit 2026

Yale Ventures

Jaya Dadwal

forEVA

FDA: Essure Permanent Birth Control

"Problems Reported with Essure"

Jennifer McFadden

"Women's Health Strategy for England" A UK government report including the finding that 84% of women report that their voices have not been listened to in the healthcare system.

Polyendocrine metabolic ovarian syndrome (PMOS)

Monique Rainford

Megan Ranney and Monique Rainford: "Opinion: Over-the-counter birth control pill could make a huge difference"

Enrich Health

Monique Rainford: Pregnant While Black: Advancing Justice for Maternal Health in America

Sejal Hathi: "Nine Months of Medical Attention. Then Almost Nothing"

Kimberley Steele

Advanced Research Projects Agency for Health (ARPA-H)

Lymphatic System: Function, Conditions & Disorders

ARPA-H: Lymphatic Imaging, Genomics, and Phenotyping Technologies (LIGHT)

ARPA-H: Groundbreaking Lymphatic Interventions and Drug Explorations (GLIDE)

"GLIDE set to prevent and cure human disease by targeting the lymphatic system"

Yusuf Ransome

Yusuf Ransome on LinkedIn: "The hardest part of building a solution is when your own family depends on it"

SOCAH Lab

Pew Research: "Spirituality Among Americans"

Janani Ramaswamy

"Arvinas Announces FDA Approval of VEPPANU (vepdegestrant) for the Treatment of ESR1m, ER+/HER2- Advanced Breast Cancer"

Arvinas

Yale Ventures: Accelerators, Programs, and Innovation Centers

HealthTech Works

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.

Howie and Harlan are joined by Nicholas Christakis, director of Yale's Human Nature Lab, to discuss his research on social networks, human connection, and the forces that help societies cooperate and endure. Harlan discusses promising phase 3 results for retatrutide, Eli Lilly's experimental "triple G" obesity drug; Howie provides an update on the fast-growing Ebola outbreak in the Democratic Republic of Congo.

Show notes:

Obesity Drugs

"Lilly's triple agonist, retatrutide, delivered powerful weight loss in pivotal Phase 3 obesity trial"

"Triple–Hormone-Receptor Agonist Retatrutide for Obesity—A Phase 2 Trial"

Bariatric surgery

Nicholas Christakis

Human Nature Lab

Nicholas Christakis: Blueprint: The Evolutionary Origins of a Good Society

Free rider problem

Phenotype

Stephen Pinker

The Enlightenment

Nicholas Christakis on YouTube: For the Love of Science

Nicholas Christakis: "The Spread of Obesity in a Large Social Network Over 32 Years"

Social contagion

Altruism

Wet lab vs. dry lab

Microbiome

Communicable vs. non-communicable diseases

Nicholas Christakis: "The Collective Dynamics of Smoking in a Large Social Network"

Nicholas Christakis on YouTube : "Learning in a Time of War"

Tymofiy Mylovanov

The president of the Kyiv School of Economics, who invited Christakis to lecture in Ukraine.

Ebola

CDC: Ebola Disease 2026

CDC: Ebola Disease Basics

"The Ebola virus spreading in Congo is a rare species with no vaccines or treatments"

Hypertension

Watch last week's episode on YouTube.

In the Yale School of Management's MBA for Executives program, you'll get a full MBA education in 22 months while applying new skills to your organization in real time.

Yale's Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings.

Email Howie and Harlan comments or questions.