Podcast
Hormones, Metabolism & You!
Your hormones control everything—from energy levels to weight, mood, and overall health. But understanding them shouldn’t feel like decoding a medical textbook. Welcome to Hormones, Metabolism & You!, the podcast where board-certified endocrinologist Dr. Cassie Smith breaks down the science behind your body’s most powerful regulators.
Each week, Dr. Smith tackles the real questions about metabolism, weight management, thyroid health, menopause, PCOS, insulin resistance, and more—giving you clear, actionable insights to take charge of your health. Whether you’re struggling with stubborn weight, feeling fatigued, or just want to optimize your well-being, this podcast is your go-to resource for evidence-based advice, practical tips, and expert interviews.
It’s time to understand your hormones, master your metabolism, and feel your best—because when your body is in balance, you thrive!
🎧 Subscribe now and start your journey to better health!
- Medicine chart
- #146
- Episodes
- 135
- Releases
- Weekly
- Typical length
- 51 min
- On air since
- 2024
- Latest episode
- 2 days ago
Episodes
135 episodes, newest first
-
48 min
135. Gut Health, Mold, and Hormones: The Missing Pieces of Your Health
Show notes
Amanda Soukoulis joins me to talk about how her health unraveled in her 20s despite elite training and a clean diet, and what it took to rebuild it. We talk about gut dysfunction, mold exposure, and chronic stress, and why a “normal” lab result doesn’t always tell the full story.
We also get into hormones, dietary fat, sleep, and where peptides like Epitalon, VIP, BPC-157, TB-500, and MOTS-c fit once the foundation is in place. Amanda explains why peptides amplify the environment they enter, why the order of healing matters, and why working with a provider is important.
Topics We Cover in This Episode:
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Why “normal” and “optimal” lab ranges aren’t the same thing
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What a health breakdown can look like in your 20s
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How physical, emotional, dietary, and environmental stress add up
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Why detox pathways and gut health come before a mold protocol
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The many ways mold exposure can show up in the body
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Why peptides only amplify the environment they enter
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How to think about layering and stacking peptides
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Why reputable sources and a monitoring provider matter
If you’ve been feeling tired, foggy, or like your symptoms don’t add up, tune in to this conversation with Amanda Soukoulis, then subscribe and share it with someone who needs to hear it.
Resources & Links
Get Your FREE Precision Pathway
DM Amanda “MODERNENDOCRINE” on Instagram (@amandasouks) to receive:• The Peptide Playbook: a practical guide to the most effective peptides, what they do, who they’re for, and how to use them strategically to support your health and performance goals.
• A 1:1 Custom Blueprint Session to map the highest-impact strategy for your unique health and performance goals.IG: https://www.instagram.com/amandasouks
TikTok: https://www.tiktok.com/@amandasouks
LinkedIn: https://www.linkedin.com/in/amanda-soukoulis/
YouTube: https://www.youtube.com/@amandasouksLearn More About the U³ System™: https://amandasoukoulis.com/the-u3-system
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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1 hr
134: Is It Really ADHD or Something Else? The Hidden Causes Behind Focus Problems in Kids and Adults
Show notes
Dr. Brandon Crawford, a functional neurologist and founder of Neuro Solutions Center in Austin, joins me to talk about what can look like ADHD in kids and adults, and why focus problems, anxiety, and restlessness may have roots beyond the diagnosis itself. We talk about light, circadian rhythm, and how brain networks and cellular energy fit into the picture.
We also get into what parents can look at first when a teacher raises concerns about attention, including sleep, light, food, movement, and screens. Dr. Crawford explains photobiomodulation in plain English, and we talk about how it connects to thyroid, insulin, and hormone health, plus his perspective on stimulants and medication.
Topics We Cover in This Episode:
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Why ADHD, anxiety, and chronic fatigue can look so similar
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What functional neurology looks at that a standard ADHD evaluation may not
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How light exposure shapes mood, sleep, and focus
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The light level Dr. Crawford asks families to stay under after sunset
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Why a child's behavior at school may not tell the whole story
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What to look at first if a teacher says your 5-year-old has attention issues
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Photobiomodulation, explained in plain English
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How focus, thyroid, insulin, and hormones may be connected
If you've been wondering whether ADHD is the whole story for you or your child, tune in to this conversation with Dr. Brandon Crawford.
Resources & Links
Connect with Dr. Brandon Crawford on Instagram @bcrawforddc: https://www.instagram.com/bcrawforddc/
Neuro Solutions Center: https://www.neurosolutionatx.com/
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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57 min
133: From Burnout to Balance: Understanding Cortisol, Oxytocin & Women’s Hormones
Show notes
Dr. Anna Cabeca joins me to talk about why so many midlife women are told their labs are normal while they feel exhausted, foggy, and out of step with their own bodies. We talk about what shifts in perimenopause, how falling progesterone and insulin resistance can show up as everyday symptoms, and why Dr. Cabeca treats hormone imbalance as a metabolic question first.
We also look at how cortisol and oxytocin work together, what burnout can look like physiologically, and simple ways to support oxytocin. From there we get into keto and urine pH, what the research says about hormone therapy, and how the vaginal and urinary microbiome may relate to bladder symptoms.
Topics We Cover in This Episode:
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Why "normal" labs don't always mean you feel normal
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What happens to progesterone and estrogen between ages 35 and 50
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Why hormone symptoms may start as metabolic ones
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How cortisol and oxytocin interact, and what burnout can look like
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Free, everyday ways to support oxytocin
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Why keto doesn't work the same way for every woman
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What the research says about hormone therapy, and why the environment matters
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How the vaginal and urinary microbiome may connect to bladder symptoms
If you've been feeling tired, foggy, or dismissed when your labs come back normal, tune in to this conversation with Dr. Anna Cabeca. Subscribe so you don't miss an episode, and share it with a friend who needs to hear it.
Resources & Links
Connect with Dr. Anna Cabeca: https://drannacabeca.com
Connect with Dr. Anna on Facebook: https://www.facebook.com/DrAnnaCabeca
Connect with Dr. Ana on IG: https://www.instagram.com/thegirlfrienddoctor
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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58 min
132: The Chemical Load We Carry: Toxins, EMFs & Hormonal Health
Show notes
What if I told you right now, this very moment, your body is carrying a chemical load that you have never been tested for, never been warned about, and never asked for? In this episode, I’m joined by Nick Pineault, author of The Non-Tinfoil Guide to EMF and creator of the documentary Body Burden: The Toxins We Carry, to talk about what “body burden” actually means and how the chemicals we encounter through our food, water, air, plastics, household products and technology may intersect with hormones, metabolism and overall health.
We talk about how environmental medicine approaches toxic exposure, when testing may be useful, what Nick learned from discovering his own elevated lead, mercury and mycotoxin levels, and why reducing exposure may matter just as much as focusing on detoxification. We also get practical about plastics, water filtration, sleep, EMFs, sweating and elimination—and discuss why looking at the cumulative burden, rather than searching for one single toxin to blame, may be the more useful way to think about environmental health.
Topics We Cover in This Episode:
•
What “body burden” actually means—and what can accumulate over time
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Why testing for specific toxins can be more complicated than it sounds
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What Nick discovered when he tested his own body burden
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Why reducing exposure comes before trying to “detox”
•
How plastics and endocrine-disrupting chemicals may intersect with metabolism
•
The connection Nick sees between EMFs, sleep and other environmental stressors
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Simple changes that can reduce everyday exposure
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Why environmental medicine takes a systems-based approach
If you’ve ever wondered whether the environment around you could be affecting your hormones, metabolism, sleep or energy, this conversation gives you a lot to think about without turning it into another list of things to fear.
Resources & Links
Find more about Nick at http://theemfguy.com
Body Burden: The Toxins We Carry https://ngmdiainc.ontralink.com/t?orid=315604&opid=61
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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1 hr
131: Cell Care Over Self-Care: A New Way to Think About Your Health
Show notes
Dr. Monisha Bhanote joins me to talk about cellular health and resilience, and why fatigue, brain fog, digestive issues, and other everyday symptoms may be signals from our cells rather than things we should simply accept. We talk about her approach to cell care, cellular consciousness, and why health practices need to be personalized rather than copied from the latest trend.
We also explore why Dr. Bhanote considers travel a stress test for the body, how digestion, immunity, focus, energy, and recovery are connected, and what Ayurveda can teach us about listening to those signals. We also talk about muscle, mitochondria, and creating health rituals that work with your body instead of against it.
Topics We Cover in This Episode:
•
What cellular resilience actually means
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How to recognize the signals your body is sending
•
Why travel can stress multiple systems at once
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The five pathways connected to resilience
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How Ayurveda can inform personalized health choices
•
Why copying someone else's wellness routine may backfire
•
How muscle supports cellular health
•
A simple exercise for becoming more aware of your body
If you’ve been feeling tired, foggy, or like your body just isn’t responding the way it used to, tune in to this conversation with Dr. Monisha Bhanote.
Resources & Links
Connect with Dr. Monisha Bhanote: https://www.drbhanote.com/
Travella Wellness Products: https://travelawellness.com/ (Use code: DRCASSIE)
The Anatomy of Well-Being Book: https://www.drbhanote.com/the-anatomy-of-wellbeing
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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1 hr 1 min
130: Why Your Hormone Protocol Isn’t Working: Mold, Lyme & Chronic Inflammation
Show notes
What happens when you’re doing all the “right” things for your hormones and health, but you still don’t feel better? In this episode, I sit down with Dr. Neil Nathan to explore why underlying factors like mold, Lyme disease, inflammation, nervous system dysregulation, and detoxification challenges may complicate treatment.
We also talk about why some patients react unexpectedly to hormones or supplements, how Dr. Nathan approaches complex chronic illness, and why looking beyond the obvious diagnosis can sometimes change the conversation.
Topics We Cover in This Episode:
•
Why hormone protocols don’t always work as expected
•
How mold and Lyme may affect the immune system
•
Why “detox” isn’t a one-size-fits-all approach
•
What persistent or unusual symptoms may be telling you
•
How inflammation can present differently from person to person
•
What cytokine testing can reveal
•
Why environmental exposure matters
•
When it may be time to look deeper
If you’ve experienced persistent symptoms, unexpected reactions to treatment, or the frustration of doing everything “right” and still not feeling better, this is a conversation you’ll want to hear.
Resources & Links
Connect with Dr. Neil Nathan: https://neilnathanmd.com/
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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49 min
129: Why Is Testosterone Still Off-Limits for Women?
Show notes
Testosterone in women is finally getting more attention, but what does that actually mean for women and their care? In this episode, I sit down with Dr. Terri DeNeui to discuss the FDA’s focus on testosterone, why there still isn’t an FDA-approved testosterone treatment specifically for women, and the questions surrounding safety, dosing, and access.
We also talk about symptoms of testosterone deficiency, why “normal” lab ranges don’t always tell the full story, and the larger conversation around medical freedom and individualized care.
Topics We Cover in This Episode:
•
Why testosterone matters for women
•
What the FDA is currently considering
•
Why testosterone remains a controlled substance
•
When symptoms can appear
•
Why “normal” labs may not tell the whole story
•
How dosing and delivery methods matter
•
Where medical freedom fits into the conversation
Tune in to hear Dr. Terri DeNeui’s perspective on where women’s testosterone care stands today, what still needs to change, and what patients should be asking.
Resources & Links
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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43 min
128: Viral Hormone Trends: What’s Actually Worth Your Time?
Show notes
Social media is full of hormone hacks promising better energy, easier weight loss, balanced hormones, and fewer symptoms. But how much of it is actually backed by science? In this episode, I’m breaking down seven viral trends, including cortisol cocktails, fiber maxing, pink salt, metabolism morning routines, and “hormone-balancing” foods, and separating reasonable health habits from overhyped claims.
I also talk about the way social media approaches PCOS and perimenopause, and why oversimplifying complex hormone conditions can do more harm than good. If you’ve ever wondered whether the latest hormone trend is worth trying, this conversation will help you look at these claims with a little more context and a lot less TikTok influence.
Topics We Cover in This Episode:
•
Why cortisol cocktails aren't what they claim to be
•
The problem with suddenly “fiber maxing”
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What pink salt can actually do for you
•
Whether a metabolism morning routine works
•
The truth behind “hormone-balancing” foods
•
Why PCOS weight-loss advice needs more nuance
•
When a viral trend may be masking a bigger issue
Tune in, subscribe to Hormones, Metabolism and You, and share this episode with someone who could use a little more context the next time a hormone hack hits their feed.
Resources & Links
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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48 min
127: Birth Control Masterclass: The Mash-Up Every Woman Needs to Hear
Show notes
In this mash-up episode, I’m bringing together key conversations about birth control, PCOS, PMS, and the hormonal changes women experience from their 20s through perimenopause.
We unpack why birth control is so often used to manage symptoms, what it may be masking, and how hormones like estrogen, progesterone, testosterone, insulin, and cortisol all fit into the bigger picture. We also talk about the different birth control options women may consider as they get older and why the right approach can change throughout different stages of life.
From painful and irregular periods to PCOS, weight struggles, low libido, anxiety, fatigue, and the transition into perimenopause, this mash-up brings together the questions women are asking and the answers they deserve to hear.
Topics We Cover in This Episode:
•
Why birth control may be masking more than you realize
•
The hormone connection behind PCOS and weight struggles
•
What your period could be trying to tell you
•
Why your 30s and 40s can bring unexpected changes
•
The connection between cortisol, insulin, and androgens
•
When painful or irregular periods deserve a closer look
•
How gut health and stress fit into the hormone picture
•
Why the same treatment may not make sense at every age
Tune in for the full mash-up and hear these conversations come together in one place. You may walk away with a very different perspective on birth control, your symptoms, and the questions you should be asking about your own health.
Resources & Links
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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49 min
126: Health Care is So Broken - 3 Typical Patient Cases
Show notes
The healthcare system is not designed to keep you well, and I am done pretending that is okay. In this episode, I am breaking from the usual format to talk honestly about why I believe healthcare in the United States has become so reactive instead of preventative, and how that approach is leaving people sick, frustrated, and without answers.
I share my perspective as both a patient and a provider, including the ways insurance companies, healthcare systems, limited appointment times, and a diagnosis-by-diagnosis approach can keep providers from looking at the whole person. I also explain why symptoms and lab results cannot always be viewed in isolation, because our bodies do not operate in silos.
Then, I walk through three patient scenarios that I see repeatedly in my practice: a 19-year-old struggling with PCOS symptoms and insulin resistance, a woman in her 30s dealing with fatigue, weight gain, sleep issues and brain fog who was told her labs were normal, and a woman in her 40s experiencing perimenopausal symptoms who was told she was too young for hormones. These stories reveal just how much can be missed when we only look at whether a number falls inside a laboratory's "normal" range instead of asking whether it actually makes sense for the person sitting in front of us. Most importantly, I want you to leave this episode knowing that you are not crazy, your symptoms matter, and you can become your own best advocate when the system isn't listening.
Topics We Cover in This Episode:
•
Why "normal" lab results may not tell the whole story
•
The connection between symptoms that seem completely unrelated
•
What three very different patients had in common
•
Why the approach to preventative care needs to change
•
The piece of the puzzle that can be missed when diseases are treated separately
•
Why some women are told they are fine when they know something isn't right
•
What it really means to become your own best health advocate
•
Why waiting until something is completely broken may be costing you years
Resources & Links
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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1 hr 6 min
125: How to Dementia-Proof Your Brain: Dr. David Perlmutter on Hormones, Gut Health, and Inflammation
Show notes
What if protecting your brain starts decades before memory problems ever appear? In this conversation, I sit down with neurologist and bestselling author Dr. David Perlmutter to talk about what current research says about dementia prevention, why metabolic health may play a much larger role than many people realize, and why waiting until cognitive symptoms develop may be waiting too long. We get into the connection between blood sugar, insulin resistance, inflammation, gut health, sleep, exercise, and brain function, along with why so many of these risk factors begin showing up in our 30s and 40s rather than later in life.
We also spend time on topics that generate a lot of questions in my practice, including hormone therapy, women's brain health, alcohol, stimulants, and the current state of dementia treatments. Dr. Perlmutter shares his perspective on why prevention deserves more attention, how lifestyle interventions fit into the conversation alongside medical care, and what practical markers people can monitor to better understand their long-term brain health.
Topics We Cover in This Episode:
•
Why brain health may be shaped long before memory loss ever begins
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How metabolic health and inflammation may influence cognitive function
•
The relationship between gut health, sleep, and long-term brain resilience
•
Why women face unique considerations when it comes to dementia risk
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How Dr. Perlmutter views bioidentical hormone therapy in the context of brain health
•
What current evidence suggests about alcohol, stimulants, and cognitive wellness
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Which everyday health markers may provide insight into future brain health
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Why prevention may be more impactful than waiting for symptoms to appear
If you're interested in protecting your brain health for the long term and understanding how everyday lifestyle choices fit into that picture, I think you'll love this episode.
Resources & Links
Connect with Dr. Perlmutter: https://drperlmutter.com/
Brain Defenders: http://braindefenders.com/
Follow on IG: https://www.instagram.com/davidperlmutter/
Follow on YouTube: https://www.youtube.com/user/DavidPerlmutterMD
Connect on X: https://x.com/davidperlmutter
Connect on LinkedIn: http://linkedin.com/in/david-perlmutter-md
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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51 min
124: Heart Disease Myths Exposed: Statins, LDL, Estradiol, Testosterone, & the Truth
Show notes
Heart disease is still the leading cause of death, yet many people are left wondering whether they're focusing on the right risk factors.
In this episode, I sit down with board-certified cardiac surgeon Dr. Philip Ovadia to discuss how his perspective shifted from treating advanced heart disease in the operating room to helping people prevent it in the first place.
We talk through common questions about cholesterol, LDL, statins, coronary calcium scores, and why he believes heart health requires looking beyond a single lab value to better understand metabolic health, inflammation, and insulin resistance.
Topics We Cover in This Episode:
•
What LDL cholesterol can and cannot tell you about heart disease risk
•
How insulin resistance and inflammation fit into the bigger picture
•
When a statin may make sense and when other factors deserve attention first
•
The current conversation around bioidentical hormones and cardiovascular health
•
Who should consider a coronary artery calcium scan and what the results can tell you
•
Why metabolic health may be one of the most important pieces of heart disease prevention
•
Practical questions to ask when evaluating your own cardiovascular risk
Resources & Links
Take the Quiz with Dr. Ovadia: https://ifixhearts.com/
Order Dr. Ovadia’s Books: https://ifixhearts.com/books/
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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1 hr 5 min
123: Hashimoto’s, Thyroid Labs, and Exercise: Are You Helping Your Body or Stressing It More?
Show notes
If you have Hashimoto’s and feel like you’re doing everything “right” but somehow feeling worse, this episode is for you. I’m answering your most frequently asked questions about Hashimoto’s, exercise, thyroid labs, thyroid antibodies, medication adjustments, estrogen, and why symptoms don’t always match what your lab work says. Throughout our conversation, I explain why looking at one lab value or one symptom in isolation often leads to frustration, and why understanding the bigger picture is essential when managing thyroid disease.
I also share ways to think about exercise, recovery, inflammation, medication tolerance, and the relationship between your thyroid, gut, hormones, metabolism, and stress response.
Topics We Cover in This Episode:
•
Why exercising harder isn't always the best strategy for Hashimoto's
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How to recognize when your workouts are exceeding your body's recovery capacity
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Why thyroid antibodies can fluctuate without necessarily signaling that your condition is worsening
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How to interpret thyroid labs alongside symptoms instead of viewing them separately
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The connection between stress, gut health, blood sugar, hormones, and thyroid function
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Why some people feel overstimulated on thyroid medication even when their labs suggest they need more
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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48 min
122: Drain Before You Detox: The Missing Link Between Gut Health, Hormones, & Mold Recovery with Marina Ortega (The Poop Fairy)
Show notes
If you're dealing with constipation, bloating, brain fog, or you feel like every detox protocol makes you feel worse instead of better, this conversation is for you.
In this episode, I'm joined by Marina Ortega, founder of Scottsdale Hydrotherapy and co-founder of Trust Your Gut, to talk about one piece of healing she believes is often overlooked: supporting your body's drainage pathways before asking it to detox. Marina shares her own journey through chronic constipation, mold exposure, and years of searching for answers before becoming a gut health educator.
We also discuss what colon hydrotherapy actually is, how the lymphatic system, bile flow, and bowel function work together to support the body's natural detox pathways, and why so many people struggle to feel better even after trying supplements and cleanses. Marina also shares what she learned while recovering from severe mold exposure, her perspective on tools like castor oil packs and coffee enemas, and why she believes the gut-brain connection is an essential part of lasting healing.
Topics We Cover in This Episode:
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Why Marina says drainage should come before any detox protocol
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What colon hydrotherapy actually involves—and what to expect during a session
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How constipation can impact hormones, brain fog, and overall health
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The connection between the lymphatic system, bile flow, and detoxification
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What Marina learned from recovering from severe mold exposure
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How castor oil packs and coffee enemas fit into her wellness approach
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Why stress and nervous system regulation can show up as digestive symptoms
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Simple ways to support your body's natural elimination pathways
Resources & Links
Trust Your Gut: https://www.trustyourgut.shop/
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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48 min
121: Why Successful Men Are Secretly Running Themselves into the Ground: What Every Man and Spouse Needs to Hear
Show notes
What does it really mean when a man starts feeling constantly exhausted, loses motivation, struggles with brain fog, or notices changes in his physical and sexual health?
In this episode, I sit down with Dr. Stephen Sanders, founder of Whole Men's Health, to talk about why these symptoms deserve more attention and why men's health is about far more than testosterone alone. We discuss the growing number of younger men experiencing hormone and metabolic challenges, how stress, sleep, nutrition, relationships, and modern lifestyles all intersect, and why so many men delay asking for help until their symptoms become impossible to ignore.
Topics We Cover in This Episode:
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Why fatigue and brain fog may signal more than simply getting older
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The symptoms many men experience long before they seek medical help
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How stress, sleep, gut health, and hormones influence one another
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Why conversations about men's health often happen later than they should
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Practical ways couples can support each other's long-term health
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Why tracking biomarkers matters, even when you feel "fine"
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The foundational habits that consistently outperform the latest health trends
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How to approach sensitive health conversations with empathy instead of judgment
If you're looking for a thoughtful conversation about men's health, relationships, and the habits that support long-term well-being, I hope you'll join us for this episode.
Resources & Links
Connect with Dr. Stephen: https://www.wholemenshealth.com/
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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33 min
120: From PCOS to PMOS; Why Hormones Are Not the Only Problem
Show notes
In this interview with Terri DeNeui, we explore why the conversation around PCOS is shifting toward a broader understanding of metabolic health with the emerging term PMOS.
Rather than viewing irregular cycles, infertility, and hormone imbalances as isolated ovarian problems, we discuss how insulin resistance, gut health, inflammation, stress, and lifestyle factors may be driving many of the symptoms women experience. I also share why this updated perspective could change the way clinicians evaluate and support patients across different stages of life—not just during their reproductive years.
We also spend time talking about practical treatment considerations, from comprehensive lab testing and lifestyle interventions to the appropriate role of GLP-1 medications.
Topics We Cover in This Episode:
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Why some experts are moving from the term PCOS to PMOS—and what that shift represents
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How insulin resistance and gut health may influence hormone balance
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Why irregular menstrual cycles deserve a broader metabolic evaluation
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The role inflammation and stress may play in hormone-related symptoms
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Why body composition can be a more meaningful measure than weight alone
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How to think about GLP-1 medications as one tool rather than a complete solution
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Practical lifestyle habits that support long-term metabolic and hormonal health
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Why treating symptoms without addressing underlying metabolic dysfunction may leave important questions unanswered
If you're interested in a more comprehensive way of thinking about hormones, metabolism, and women's health, I think you'll find this conversation both practical and thought-provoking.
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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1 hr
119: Beyond Sick Care: Why Insurance Isn’t Coming To Save You
Show notes
For many people, the healthcare system becomes frustrating long before they receive a diagnosis. Symptoms are dismissed, lab work comes back "normal," and the next step is often another prescription rather than a conversation about why those symptoms developed in the first place.
In this episode, I'm joined by board-certified anesthesiologist and hormone optimization specialist Dr. Mike Fortunato to discuss his journey from conventional medicine into functional medicine, and why he believes many patients are looking for something today's healthcare model wasn't designed to provide.
Our conversation explores the realities of practicing medicine inside an insurance-driven system, the role hormones play in long-term health, and what Dr. Mike observed after years of caring for increasingly unhealthy surgical patients.
Topics We Cover in This Episode:
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Why "normal" lab results don't always reflect optimal health
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How Dr. Mike's own health challenges changed the way he practices medicine
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What anesthesiology taught him about the declining health of today's patients
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Why hormone optimization is about more than treating symptoms
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How insurance influences the care many patients receive
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The role lifestyle plays alongside hormone health
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Why prevention often receives less attention than disease management
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How patients can become stronger advocates for their own health
If you've been searching for a broader perspective on healthcare, hormones, and long-term wellness, I hope you'll join us for this conversation.
Dr. Mike’s Resources & Links:
💻 Optimize MD: https://optimizemd.health
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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55 min
118: Stop Starving, Start Healing: The Real Root Cause of Weight Loss Resistance
Show notes
What if the reason you're struggling with weight, low energy, or hormone symptoms isn't just about eating less and exercising more?
In this episode, I sit down with functional medicine practitioner Dani Conway to talk about the bigger picture of metabolic health. We discuss why so many women are told their lab work is "normal" even when they still feel exhausted, inflamed, or stuck, and why looking beyond the scale often leads to better answers.
Dani shares how her own health journey shaped the way she now helps women address gut health, hormones, inflammation, and metabolism with a personalized, root-cause approach rather than a one-size-fits-all plan.
We explore the role digestion and detoxification play before focusing on hormones, why testing matters more than guessing, and how factors like stress, sleep, nervous system regulation, nutrition, exercise, and even peptide therapy fit into the conversation.
Topics We Cover in This Episode:
•
Why gut health and detoxification may need attention before addressing hormone balance
•
How to recognize signs that your body may not be processing nutrients or toxins efficiently
•
Why "normal" lab results don't always tell the whole story
•
What comprehensive testing can reveal beyond standard blood work
•
Why stress and nervous system regulation can influence weight loss, even with healthy habits
•
How to think about nutrition and exercise without relying on one-size-fits-all advice
If you're looking for a more personalized way to think about hormones, metabolism, and sustainable health, I think you'll find plenty to consider in this conversation.
Resources & Links
Instagram: @daniconwayofficial
Website: https://nutritionthenaturalway.com/
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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54 min
117. Perimenopause Is Wild: Symptoms, Support, and What Actually Helps
Show notes
Perimenopause and menopause affect every woman, yet many are still caught off guard by the wide range of symptoms that can come with this stage of life. In this episode, I sit down with nutritionist, menopause researcher, and author Andrea Donsky to discuss what she's learned from studying thousands of women and why so many continue to feel confused, dismissed, or unsupported when seeking answers. We explore common symptoms like fatigue, brain fog, sleep disruption, anxiety, memory issues, and weight changes, along with some of the lesser-known experiences that often go unrecognized.
Andrea also shares her personal journey through perimenopause, the inspiration behind her book Nourishing Menopause, and practical ways women can better support themselves through nutrition, lifestyle habits, mindset, and self-advocacy. This conversation offers reassurance, validation, and a reminder that while every woman's experience is different, no one has to navigate it alone.
Topics We Cover in This Episode:
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Why perimenopause symptoms are often overlooked or misunderstood
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The most common symptoms women report experiencing
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What Andrea's research reveals about women's experiences with healthcare providers
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Why hot flashes aren't always the first sign of hormonal change
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The connection between stress, sleep, hormones, and weight fluctuations
•
How mindset can influence the menopause experience
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Why community and shared experiences matter during this transition
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Practical ways to better support your body through perimenopause and menopause
If you've been questioning changes in your mood, energy, sleep, memory, or weight, I hope this conversation helps connect some of the dots. Perimenopause and menopause can feel isolating, but understanding what's happening is often the first step toward feeling better.
Resources & Links
Connect with Andrea @andreadonsky
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
-
58 min
116: What Screen Time Is Really Doing to Your Eyes, Brain, and Stress Levels
Show notes
One of the most overlooked aspects of health may be influencing how you think, learn, focus, perform, and even respond to stress every single day. In this episode, I sit down with neuro-optometrist Dr. Bryce Appelbaum to explore the difference between eyesight and vision, and why seeing 20/20 doesn't necessarily mean your visual system is functioning optimally. We discuss how the eyes and brain work together, the role vision plays in learning, reading, athletic performance, spatial awareness, and everyday confidence, and why many functional vision problems often go unrecognized.
We also spend time talking about something that affects nearly all of us: screen time. Dr. Appelbaum explains what prolonged screen exposure is doing to our visual system, nervous system, sleep, stress response, and overall well-being.
Topics We Cover in This Episode:
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How eyesight and vision are related, and why they're not the same thing
•
The subtle signs that may point to an underlying functional vision problem
•
Why screen fatigue may involve much more than tired eyes
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What vision has to do with focus, learning, reading, and information processing
•
The connection between visual function, stress, and nervous system regulation
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Why some people struggle with motion sickness, bridges, tunnels, or spatial awareness
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How vision training differs from traditional eye care approaches
•
Simple daily habits that may help support long-term visual health
Whether you're a parent, athlete, professional, avid screen user, or simply interested in optimizing your health, this conversation offers a fascinating perspective on the connection between vision and whole-body wellness.
Resources & Links
📚Get the Free Vision Health Guide: https://www.screenfit.com/5-proven-secrets-to-relieve-eye-strain
📝Free Vision Assessment: http://www.myvisionfirst.com/quiz
🫰🏻 $200 off ScreenFit™ using code DRCASSIE at http://screenfit.com/enroll
😎 10% off Digital Performance Lenses using code DRCASSIE at http://shop.myvisionfirst.com/
If you want to check out ScreenFit™ to see the exercises DrB talks about firsthand, you can log in with a backstage pass here.
📲 Follow Dr. Bryce Appelbaum
Instagram: @drbryceappelbaum
Youtube: https://www.youtube.com/@drbryceappelbaum
Facebook: https://www.facebook.com/myvisionfirstoptometry
Linked in: https://www.linkedin.com/in/dr-bryce-appelbaum/
Tik Tok: https://www.tiktok.com/@dr.bryceappelbaum
Order Dr. Cassie’s Book ‘Fix Your Gut, Fix Your Hormones’: https://guthormonefix.com/
Use code LISTEN10 for 10 % off your order on http://shopmodernendocrine.com
📲 Follow Dr. Cassie Smith & Modern Endocrine
💻 Website: https://www.modern-endocrine.com/
📸 Instagram: https://www.instagram.com/modernendocrine_/
🌟 Facebook: https://www.facebook.com/ModernEndocrine
📽️ YouTube: https://www.youtube.com/@modernendocrine
🕹️ TikTok: https://www.tiktok.com/@modernendocrine?lang=en
📰 Newsletter: https://linktr.ee/modernendocrine
➡️ Disclaimer: https://www.modernendocrineokc.com/disclaimer-6353
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