Peptide of the Week| Weight Loss, Health & Wellness

Follow us on social media: JD's Socials:
https://hoo.be/jddenhamofficial
Will's Socials: https://hoo.be/williamthaas
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Warrior Coaching: https://www.warrior-makerscoaching.com
Peptide Of The Week Website: https://peptideoftheweekpod.com

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

After two episodes with the inventor, JD Denham and William T. Haas break down FLGR-242 and Klotho from their own experience. JD has run FLGR-242 for two and a half months, they both have Klotho in their stack, and they give you the real results, the side effects nobody is talking about, and the one overdose warning you need to hear before you inject.

🔬 Topics Covered:
• Why FLGR-242 is the first peptide people say can rival gear
• Myostatin explained: your body's built-in brake on muscle growth and fat burning
• FLGR-242 vs Follistatin-344 and why selectivity matters
• The albumin binder: how it makes these compounds last for weeks
• Claimed results of 10 to 14 pounds of muscle in 3 to 4 months
• JD's honest 2.5 month review, including the extreme hunger
• Why the hunger can't be timed around a once a week injection
• FLGR-242 dosing: 5mg per week for men, about 2.5mg for women
• Why going above 10mg per week shows diminishing returns
• FLGR-242 vs gear: where it lands compared to Anavar and Winstrol
• What Klotho does for your kidneys and why EGFR matters
• How you know Klotho is working: frequent urination and clear urine
• Klotho's reported effects on sex drive, bone health, and blood pressure
• The big Klotho warning: overdosing acts like an uncontrolled diuretic
• Klotho dosing: 10mcg every two weeks, and never more
• Why they are being cautious: brand new compounds with no controlled human studies
• Blood work first: JD's plan to test off everything before restarting

Chapters:
00:00 – Intro
00:09 – Welcome Back & China Trip Logistics
00:49 – Chinese Business Etiquette: What Not to Do
02:49 – Jet Lag & What to Expect in China
07:55 – Mom's Move & the Dog Debate
14:40 – Today's Compounds: FLGR-242 & Clotho
17:48 – Does FLGR-242 Rival Gear? Modified Follistatin Explained
21:11 – Belgian Blue Cows & Muscle-Sparing Benefits
26:52 – JD's Experience: Hunger & Real Results
29:53 – FLGR-242 Dosing for Men & Women
33:28 – Unknowns, Risks & Your Risk Tolerance
38:00 – Clotho: Kidney Function & Longevity
43:12 – How You Know Clotho Is Working
46:26 – Clotho Dosing & the Diuretic Warning
50:14 – Closing Thoughts & China Trip Outro

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

JD Denham and William T. Haas go all in on a dedicated TRT episode covering five of the most common hormone questions they get. From a 21-year-old with great total testosterone but terrible free test, to a guy down 115 pounds wondering if he even needs TRT, to the real answer on ball shrinkage and what HCG actually does about it. Plus Dave Palumbo and Alex Diego are coming on the podcast soon and JD announces the upcoming gear deep dive episode.

🔬 Topics Covered
• 21-year-old with total T of 970 but free test of only 5.6: what is actually going on and what to do about it
• Why fasting too hard and eating too little is silently killing your free testosterone at any age
• Down 115 pounds at 43 with total T of 635: can you actually be hormonally optimized without TRT?
• What does hormone optimization actually mean and why does every single peptide work better when you are there
• Why low testosterone is probably behind your anxiety, brain fog, depression and lack of sex drive and not just aging
• Is 1200 total testosterone too high and is 800 too low: the real answer for a 56-year-old on TRT
• Total testosterone is only a quarter of the picture: why free T, estrogen, SHBG and LH tell the real story
• Ball shrinkage on TRT: is it real, how bad does it get, and what does HCG actually do about it
• Should a 44-year-old switch from CJC and Ipa to actual HGH and should he start TRT based on blood work alone
• Why 10,000 steps a day is a lot harder than you think and why walking after every meal changes everything

Chapters:
00:00 – Intro
00:09 – Welcome Back & Hawaii Recap
00:39 – China Trip & Why Addicts Can Do Big Things
03:44 – Finding Your Path & Becoming a Student of Your Craft
07:22 – New Q&A Format: Structured TRT Questions
08:19 – Q&A: High SHBG & Low Free Testosterone at 21
15:57 – Q&A: Should a 48-Year-Old With 582 Total T Start TRT?
20:48 – The 10,000 Step Reality & Post-Meal Walks
25:43 – Q&A: What Does Hormone Optimization Actually Mean?
33:14 – Signs of Low Testosterone & Benefits of Optimizing
38:15 – Upcoming Guests: Palumbo, Alex Diego & a Mold Specialist
42:10 – Q&A: What Is the Optimal TRT Level at 56?
46:15 – Total vs. Free Testosterone: The Bank Account Analogy
47:58 – Q&A: Testicular Shrinkage on TRT & HCG
56:15 – Outro: Gear Episode Plans & Coaching Program

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Follow us on social media:
JD's Socials: https://hoo.be/jddenhamofficial
Will's Socials: https://hoo.be/williamthaas
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Part two with Michael Farber goes deep on FLGR-242, the long acting myostatin inhibitor he invented that is helping people gain 10 to 12 pounds of lean muscle in three to four months, without anabolics, without side effects, and regardless of genetics. This is one of the most important muscle building conversations we have ever had on this podcast.

🔬 Topics Covered:
• Why Farber invented FLGR-242 after losing 2+ years of muscle during COVID
• What myostatin actually is and why it is your body's brake on muscle growth and fat burning
• Belgian blue cows, super mice, and real world examples of myostatin mutations
• Why naturally gifted athletes often have partial myostatin mutations and do not even know it
• How FLGR-242 levels the playing field for people not born with athletic genetics
• Expected results: 10 to 12 pounds of lean muscle in 3 to 4 months at 5mg per week
• Why going above 10mg per week produces virtually no additional gains
• Farber personally went to 20mg per week and confirmed no negative health effects above 10mg
• How FLGR-242 was designed to bind ONLY myostatin and why that makes it so safe
• Why Follistatin-344 causes random growth and must be injected locally while FLGR-242 freely circulates
• Brian Johnson's myostatin experiment in Honduras: 2% gain in a year at $50,000 per try
• FLGR-242 vs circular DNA myostatin inhibitors: not even close
• Apelin-13: the ergogenic compound that optimizes fat burning and cardiovascular output simultaneously
• Long acting Thymosin Alpha-1 and Thymosin Beta coming soon
• Bioline: the new appetite and metabolism compound coming down the pipeline
• The albumin binder platform and why it is changing how every compound performs

Chapters:
00:00 – Intro
00:09 – Welcome Back & Will's Mom Moving to Town
01:24 – Appreciating Your Parents While You Have Them
03:29 – Round Two With Michael Farber: Why He Created FLGR-242
06:27 – Myostatin Inhibition Beyond Muscle: Obesity & Fetal Growth
10:02 – Leveling the Playing Field for Natural Athletes
12:21 – Real-World Results: 10–12 Pounds of Lean Muscle in 4 Months
14:44 – Dosing: Why More Than 10 mg a Week Doesn't Help
19:23 – How FLGR-242 Differs From Follistatin 344
24:06 – Safety Record & Gene Therapy Alternatives
27:55 – What's Next: Apelin, Long-Acting Thymosin & Obesity Compounds
30:16 – The Albumin Binder Discovery: MC4R & Amylin Compounds
34:34 – Cancer Drug Trojan Horse Idea
36:40 – Upcoming Launches: Appetite Control & Long-Acting Thymosin Alpha-1
38:44 – Outro

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

JD Denham is live from Maui on his honeymoon while William T. Haas holds it down in the studio. This week they go deep on growth hormone in all its forms covering HGH timing for normal vs reduced pituitary function, whether stacking Tesamorelin on top of HGH is a waste of money, how to run your first steroid cycle properly, why FLGR 242 is the first compound JD says can genuinely compete with gear, and what carpal tunnel symptoms after adding Ipamorelin actually mean.

🔬 Topics Covered
• Why taking HGH at night could be silently sabotaging your biggest natural growth hormone pulse
• Is stacking Tesamorelin on top of HGH a waste of money or does it still do something unique?
• Carpal tunnel and joint pain after adding Ipamorelin at only 200mcg: bad sign or great sign?
• Running your first steroid cycle with Test and Primo: why stopping at 8 weeks is the worst mistake you can make
• Should you add FLGR 242 or IGF-1 LR3 to a steroid cycle and what actually happens when you do? • Why taking HGH on workout days only and skipping rest days is completely backwards
• MK-677 vs Ipamorelin: why one will make you eat everything in sight and the other probably won't affect your hunger at all
• Can you stack HGH, MK-677 and IGF-1 LR3 together or is that just overkill?
• Why Klotho may be the most underrated compound for anyone running gear and what it is actually doing for your kidneys
• Every single person listening should be taking glutathione and here is exactly why

Chapters:
00:00 – Intro
00:09 – Welcome Back & Live From Maui
01:49 – Why Vacation and Rest Matter
03:20 – How Muscle Actually Grows: Recovery & HGH Timing
04:58 – Training Intensity, Dorian Yates & Muscle Group Splits
11:12 – Steroids Don't Replace Hard Work
13:49 – Why Legs, Back & Deadlifts Matter
17:10 – China Trip & Shoutout to the Team
18:35 – Buying a Whole American Wagyu Cow
22:01 – Q&A: HGH vs. Secretagogues for a 34-Year-Old Woman
28:46 – Q&A: Ipamorelin Carpal Tunnel & Joint Pain
34:19 – Q&A: Stacking HGH With Tesa, Ipa & Sermorelin
41:35 – Q&A: Peptides While Running Test & Primo
56:10 – Q&A: HGH, MK-677 & IGF-1 LR3 Timing
1:03:11 – Q&A Format Feedback, Skool & Outro

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Follow us on social media:
JD's Socials: https://hoo.be/jddenhamofficial
Will's Socials: https://hoo.be/williamthaas
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

This is not a conversation about peptides. This is a conversation with the man who invented two of the most talked about longevity compounds on the planet. Dr. Michael Farber joins JD Denham and William T. Haas to break down Klotho and FLGR-242 from the ground up. Who created them, why he created them, how they actually work in the body, and where medicine is heading in the next 20 years.

🔬 Topics Covered:
• Who is Dr. Michael Farber and his 35 years in biochemistry and 150 patents
• Why he invented Klotho to save his own kidney after losing his right kidney in his teens
• How Klotho regulates phosphate and calcium and why that matters for kidney function
• The feedback loop of kidney disease that has never been reversible until now
• People going from an EGFR of 40 back up to 70 and beyond on Klotho
• Why Klotho makes NAD work dramatically better through the SIRT1 pathway
• Klotho and the blood brain barrier: clearing toxic plaque buildup without entering the brain
• Why Dr. Farber considers Klotho more important for longevity than FLGR-242
• How the albumin binder platform works and why it allows bi-weekly dosing
• Klotho dosing: 10 micrograms every two weeks for healthy individuals, every 11 to 12 days for kidney dysfunction
• What happens if you overdose Klotho and why it is strictly range-bound
• FLGR-242: the long-acting myostatin inhibitor that is outperforming all expectations
• Why FLGR-242 dosing is nothing like Follistatin-344 and must not be confused
• The future of medicine: synthetic organs, CRISPR, fetal genetic optimization, and living to 120
• Dr. Farber consumed a bottle of painkillers a week for decades. In the last 18 months he has taken two or three total.

Chapters:
00:00 – Cold Open: Living With Kidney Disease for 40 Years
00:45 – Intro
00:54 – Welcome Back & Meeting Dr. Michael Farber
02:50 – Why He Created Klotho: Losing a Kidney
05:10 – Klotho Results: 10 mcg & Rising eGFR
07:34 – The Albumin Binder Breakthrough
12:28 – How Klotho Works in the Body
14:53 – Klotho, NAD+ & FLGR-242 Synergy
20:13 – Cardiovascular Health & Restored Libido
21:54 – Klotho Dosing: 10 mcg Every 11–14 Days
24:52 – Separating Hype From Reality
27:14 – Overdose Risks & Checking Urine Output
29:42 – Feeling "Reborn": Life After Kidney Disease
36:30 – The Future of Longevity: Organs & CRISPR
45:12 – Outro & Part 2 Preview

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

JD Denham and William T. Haas sit down for a focused all-R episode covering the most common questions they get about "R". From whether you actually need to stop between cycles, to building a stack from scratch as a brand new female, to using R with breast cancer history, to whether Cagrilintide is worth bridging with over the holidays. Plus Dr. Mike Farber, creator of FLGR 242 and Klotho, is coming on the podcast next week and JD has been running FLGR long enough to say it is giving gear a serious run for its money.

🔬 Topics Covered
• Do your R receptors actually burn out and do you need to cycle off?
• The best way to time your R doses around the weekend when cravings hit hardest
Building a peptide stack from absolute zero as a 33-year-old female athlete
• Why taking too many peptides at once is costing you money and answers
• Hormone breast cancer history on R: what is safe and what is not
• Why fatigue on R almost always comes down to one thing nobody wants to hear
• AOD vs Tesamorelin vs HGH for a 45-year-old male trying to lose his last 20 pounds
• Does 5-Amino-1-MQ actually block NAD or is that completely backwards?
• The cognitive and fat burning stack for a 40-year-old Marine on TRT and R
• FLGR 242 is the first peptide JD says is genuinely giving gear a run for its money

Chapters:
00:00 – Cold Open: Should You Stop "R"?
01:00 – Intro
01:09 – Welcome Back & VIP Zoom Call Updates
03:44 – Website, Trusted Sources & Coaching Updates
04:59 – Upcoming Guest: Dr. Mike Farber (FLGR-242 & Clotho)
08:21 – Q&A: Bridging Between "R" Cycles With Cagrilintide
15:24 – Q&A: Building a Peptide Stack as a Beginner
28:22 – Q&A: Low Energy on Reta After Breast Cancer
38:22 – Q&A: AOD-9604 & CJC After Major Weight Loss
46:18 – Q&A: Do 5-Amino-1MQ & NAD+ Conflict?
51:41 – Outro & Next Episode Preview
52:46 – "R" Takeaways Recap

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Follow us on social media:
JD's Socials: https://hoo.be/jddenhamofficial
Will's Socials: https://hoo.be/williamthaas
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Warrior Coaching: https://www.warrior-makerscoaching.com

Peptide Of The Week Website: https://peptideoftheweekpod.com

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

They all live in the same family but they are NOT the same. JD Denham and William T. Haas break down Melanotan 1, Melanotan 2, and PT-141, what makes each one different, the real side effects nobody warns you about, and some stories that will make you think twice about your dosing before a big meeting.

🔬 Topics Covered:
• How melanin actually works and why some people tan and others burn
• Melanotan 1: the safest of the three, FDA approved as Scenesse for sun-sensitive skin conditions
• Why MT1 does not cross into the brain and what that means for side effects
• MT1 and psoriasis: real results people are seeing stacked with BPC and TB-500
• Melanotan 2: broader spectrum, crosses into the brain, tanning plus arousal plus appetite suppression
• Why MT2 causes more flushing, more nausea, and darker freckles than MT1
• Spontaneous erections on MT2 and why Will does not sleep well on it
• PT-141 discovered as a metabolite of MT2 and why it works on the brain not the blood vessels
• Why PT-141 and Cialis together may be overkill but actually makes sense
• FDA approval of PT-141 as Vyleesi for low sexual desire in women
• Why PT-141 works for both men and women when Cialis does not
• JD's wife approved. Real world experience from both of them
• Why your hormones must be optimized or none of this works the way it should
• Dosing breakdown: MT1, MT2, and PT-141 injectable and nasal spray
• Why you do NOT take any of these before a first date or an important meeting
• When to stop because your friends are telling you that you look purple

Chapters:
00:00 – Cold Open: PT-141 Stories
01:21 – Intro
01:30 – Welcome Back & Mold Recovery Update
03:28 – Upcoming Guest Dr. Mike Farber & New Peptides
06:16 – Live VIP Workout & Bicep Measuring Contest
07:46 – Carnivore vs. Carbs & Upcoming Gear Episode
09:56 – Searching Every Peptide Mention on the Website
10:57 – Social Media Bans & Industry Camaraderie
14:24 – Today’s Compounds: The Melanotan Family
15:05 – Melanotan 1: How It Tans
23:42 – Melanotan 2: Tan, Libido & Appetite
29:49 – PT-141: Arousal, Marriage & Women
38:10 – Dosing, Mixing & Nasal Sprays
42:04 – Outro, VIP Calls & Live Workout

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Warrior Coaching: https://www.warrior-makerscoaching.com
Peptide Of The Week Website: https://peptideoftheweekpod.com
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
JD Denham and William T. Haas are China bound for a peptide trade show and vendor tour. Before they head out, they sit down for a full Q&A covering anaphylaxis fear around common peptides, a terrifying Tesamorelin reaction that may have been a cardiac event, the ultimate first responder protocol, washout periods, HGH timing for law enforcement on two hours of sleep, Winstrol vs FLGR 242, overdosing 5-Amino-1-MQ, and why a 22-year-old running 300mg of test weekly needs to hear some hard truth.
🔬 Topics Covered• Is the anaphylaxis risk from Tesamorelin and MOTS-C actually as high as people claim?• Left arm pain and sweating after a Tesamorelin injection: cardiac event or bad batch?• The ultimate year-long peptide protocol for firefighters and first responders• How long should you actually take off between peptide cycles?• HGH timing for a cop waking up at 2am: morning, night or both?• Does caffeine or pre-workout actually blunt your HGH response?• Winstrol vs Masteron vs Primo: which cutter is actually worth it?• Why FLGR 242 is making JD look like he is on a steroid cycle without actually being on one• 10mg of 5-Amino-1-MQ sub Q: total waste of money or actually dangerous?• A 22-year-old on 300mg of test, R, HCG and Anavar: the honest conversation they needed to hear
Chapters:00:00 – Cold Open: Why Bodies React So Differently00:44 – Intro00:53 – Welcome Back & China Business Trip04:44 – Getting Help for Addiction & Giving Back06:51 – School, VIP Perks & Coaching Updates10:24 – Q&A: Anaphylaxis Risk With Tesamorelin, Ipamorelin & MOTS-c17:11 – Q&A: Chest Pain & Sweating After Tesamorelin22:00 – Q&A: First Responder Year-Round Stack32:32 – Q&A: How Long a Washout Period Between Stacks37:39 – Q&A: Best Time to Take HGH With a 2 AM Workout45:04 – Q&A: Is 10 mg of 5-Amino-1MQ Worth It?47:55 – Q&A: Winstrol, Test Dosing & Leaning Out59:48 – Q&A: TRT, HCG & Tesamorelin at 221:11:34 – Outro & Gear Podcast Idea

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

JD's Socials: https://hoo.be/jddenhamofficialWill's Socials: https://hoo.be/williamthaasPeptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Join The Community: https://www.skool.com/peptideresearchinstitute/aboutSubscribe to our Newsletter: https://potwnewsletter.beehiiv.com/Warrior Coaching: https://www.warrior-makerscoaching.comPeptide Of The Week Website: https://peptideoftheweekpod.com
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Most people know GHK-Cu. Very few know AHK-Cu. JD Denham and William T. Haas break down both copper peptides, how they differ, how to stack them, and why one of them may be the most underrated hair growth compound available right now.
🔬 Topics Covered:• What GHK-Cu actually is and how it was discovered• How GHK-Cu rebuilds collagen types 1, 2, and 3• Why copper levels in your body drop 50% by age 60 and what that means for your skin• The copper uglies: what to expect in the first two weeks and why you should push through• Injectable vs topical vs shampoo: which to use and when• Why you cannot overdose on the Wolverine stack the way you can when copper is in the blend• Laser facial recovery cut in half using the GHK-Cu face serum• Snap-8: why it is called Botox in a bottle and why it belongs in your serum• Microneedling protocol for face and scalp: how to do it right• What AHK-Cu is and how it differs from GHK-Cu• The three things AHK-Cu does inside the hair follicle• Hair growing back darker on AHK-Cu: what people are reporting• Why JD's folliculitis makes him the perfect use case for running both• Brand new GHK-Cu plus AHK-Cu shampoo blend: what to expect• Dosing protocol for both: 2.5mg total copper, 2 to 3x per week injectable• Why nighttime is the best time to inject healing peptides
Chapters:00:00 – Cold Open: GHK-Cu & Laser Facial Healing00:50 – Intro00:59 – Welcome Back & Mold Update05:07 – Today's Compounds, School & VIP Zoom Call Updates08:32 – GHK-Cu: The Copper Peptide Explained10:56 – Benefits: Anti-Aging, Wound Healing & Scars12:29 – Injectable vs. Topical vs. Shampoo14:53 – How to Use It: Laser Facials & Microneedling17:35 – Fun Facts: "Copper Uglies" & Injection Sting19:49 – What to Avoid & Best Stacks24:19 – AHK-Cu: How It Grows Hair29:14 – Hair Transplants, DHT & Non-Hormonal Benefits35:15 – Dosing Protocols40:12 – FLGR-242, Clotho & Why Insulin Is Dangerous44:20 – Outro & Coaching Updates

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Join The Community: https://www.skool.com/peptideresearchinstitute/aboutSubscribe to our Newsletter: https://potwnewsletter.beehiiv.com/Warrior Coaching: https://www.warrior-makerscoaching.comPeptide Of The Week Website: https://peptideoftheweekpod.com
Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
JD Denham and William T. Haas are back fresh from the Olympia where they connected with some of the biggest names in the peptide space. This week they settle the telehealth vs research peptide debate once and for all, break down how to mix multiple compounds into one syringe the right way, introduce FLGR 242 as the most exciting new muscle building peptide on the market, cover ALS protocols, foot injury dosing for a teenage athlete, osteoporosis in a 60 year old with celiac, and what to stack when you cannot gain muscle despite doing everything right.
🔬 Topics Covered• Is your telehealth rep actually lying to you about research peptides?• The one thing that exposes a fake or underdosed peptide company immediately• Why mixing the wrong peptides in one syringe could ruin your whole stack• The new muscle building peptide that is showing 23% growth in early data• Down 125 pounds and training for HYROX at 49: what his stack actually looks like• Why this 59 year old functional medicine doctor still cannot gain muscle• Peptides for a 15 year old athlete with sesamoiditis: what is safe and what is not• Can Wolverine actually target multiple pain areas at the same time?• ALS at 72: the best theoretical peptide protocol when nothing is guaranteed• Osteoporosis with celiac disease: why injectables change everything
Chapters:00:00 – Cold Open00:21 – Intro00:31 – Welcome Back & Olympia Recap03:40 – School & Coaching Program Updates06:15 – New Website & YouTube Ban Update07:58 – JD's Mold-Related Cough Update08:52 – Q&A: Telehealth vs. Research Peptides18:15 – Q&A: Combining Multiple Peptides in One Syringe25:05 – Q&A: TRT Protocol for a 21-Day Costa Rica Hike31:30 – Q&A: Reconstituting ARA-290 Properly34:31 – Q&A: Best Peptides for a BJJ Practitioner's Recovery40:24 – Q&A: Somatropin & Peptide Stack at Goal Weight45:30 – Q&A: BPC/TB500/KPV for a Teen's Foot Injury50:01 – Q&A: Peptides to Slow ALS Progression51:28 – Q&A: Wolverine Stack for Multiple Pain Points56:38 – Q&A: Osteoporosis, Celiac Disease & Outro

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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas get back to basics with two compounds that belong in almost everyone's stack. Epithalon for longevity, sleep, and cellular aging. Glutathione for detox, liver protection, and immune support. Simple, powerful, and underutilized.
Chapters:00:00 – Intro00:09 – Show Updates & Shirt Talk02:15 – Heading to the Olympia02:58 – Behind the Scenes of Bodybuilding Prep05:26 – JD's Mold-Related Cough Diagnosis07:50 – New Podcast Format & Upcoming Compounds10:01 – School & Coaching Program Updates10:41 – Carnivore vs. Macros: Finding What Works13:33 – Epitalon: Origins in Russian Bioregulator Science15:03 – Why Most Peptides Lack FDA Clinical Trials17:20 – Big Pharma's Incentives & Hidden Cures21:53 – Epitalon: Longevity, Immune Support & Sleep27:53 – What to Stack With & Avoid on Epitalon32:13 – Glutathione: Why Everyone Should Take It34:57 – Delivery Methods & Global Uses39:49 – Dosing Protocols: Epitalon & Glutathione Math
We cover:🧬 What is Epithalon?– A four amino acid synthetic peptide made of alanine, glutamate, aspartate, and glycine– One of Dr. Khavinson's Soviet bioregulators developed in the 1970s military research program– Works directly on the pineal gland, the pea-sized gland in your brain that regulates sleep and hormones– In 2026, an FDA advisory committee voted 7 to 4 to recommend adding it to the approved compound list (advisory only, not yet policy)– Cannot be patented because it is a naturally occurring compound, so there is no financial incentive for big pharma to fund large trials
🔬 What Epithalon does– Telomere lengthening: Dr. Khavinson's studies showed it extends the telomere caps on your chromosomes, theoretically slowing cellular aging. Animal models showed extended lifespan– Sleep and circadian rhythm reset: deepens sleep, reduces nighttime waking, helps reset disrupted sleep cycles. One of the top reasons people run it– Immune resilience: lowers free radical damage systemically, especially helpful for overtrained athletes and chronically stressed people
⚠️ What to avoid with Epithalon– Alcohol– High-dose melatonin (it can replace melatonin, do not stack them)– Extra sedatives while running it for sleep– Theoretical caution with active cancer due to pineal gland's role in cell regulation (not proven, just noted)– Not WADA banned but classified as a non-approved substance for tested athletes
🛡️ What is Glutathione?– Discovered in 1888, actively used in Italy to treat Parkinson's after independent human trials– Your body's master antioxidant and the most important detox compound available– Scavenges free radicals, recycles vitamins C and E so they keep working, and escorts toxins out of the body
🔬 What Glutathione actually does– Liver detox and protection: number one clinical use in Western medicine, especially post-alcohol and for fatty liver support– Parkinson's and neuroprotection: proven in human trials to protect nerves from chemotherapy damage– Immune support and long COVID recovery: being used in post-viral fatigue and long COVID protocols– Skin lightening: the number one global use. High doses will make you pale. Low doses for wellness will not
Follow us on social media:JD's Socials: https://hoo.be/jddenhamofficialWill's Socials: https://hoo.be/williamthaasPeptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas are live from South Carolina touring a 503A/503B FDA-approved compounding facility. They cover how to vet a peptide source beyond the COA, HGH as a long-term play, seborrheic dermatitis triggered by HGH, SIBO and Candida gut protocols, peptides for eye health, and longevity tools for women over 60.
Chapters:00:00 – Intro00:10 – Welcome Back & South Carolina Trip00:27 – Visiting a 503A/503B Lab02:01 – Why They Take These Trips & Dealing With Online Hate05:28 – Skool Platform & Coaching Program Updates09:42 – New Format: Feedback From Listeners10:34 – Recap: The Elkins Cattle Co Episode14:08 – Q&A: Tracking a COA to a Specific Bottle19:40 – Q&A: HGH vs. TESA/IPA Secretagogues25:36 – Q&A: Statin/Blood Pressure Meds & SS-31 for Eye Health29:02 – Q&A: HGH Causing Seborrheic Dermatitis33:59 – Q&A: Fixing SIBO & Candida39:06 – Q&A: How Much Visceral Fat Is Normal?44:05 – Q&A: Reducing Inflammation & Blood Pressure Naturally48:47 – Q&A: BAM-15 & SLU-PP-332 Coupling Explained1:01:12 – Q&A: CJC/Ipa Reactions & the Ideal Longevity Stack
We cover:• Can You Trust a COA Is From the Right Batch?: Why there's no perfect answer, why cost and transparency are the best vetting tools, and why good companies test the same batch multiple times
• HGH vs Tesamorelin —The Long Game: Why Tesamorelin still retains its visceral fat-burning properties even alongside HGH, why secretagogues are redundant on HGH, and why five-plus years is the real timeline
• HGH Causing Seborrheic Dermatitis: Why elevated IGF-1 increases sebaceous gland activity, why switching to a secretagog may reduce but not eliminate the issue, and when dropping HGH altogether is the right call
• SIBO and Candida Protocol: Why oral BPC and KPV are the foundation, the role of fasting and carnivore in starving off gut overgrowth, and why Dr. Scott and holistic practitioners are the right people to guide this
• Peptides for Eye Health After Statin Damage: Why SS-31 is the most promising compound with clinical trials behind it, and why BPC, TB-500, Epithalon, and Visalutin are also worth researching
• 8% Body Fat Firefighter Overtraining: Why one or two rest days accelerate results, why sleep and stress management outrank adding compounds, and why fasting is JD's top lean-out tool for men
• Longevity Stack for Women Over 60: Why HGH is the unanimous pick for bone density and belly fat, why SS-31 before MOTS-C is non-negotiable, and why creatine is the most underrated supplement for older women
• Klotho Peptide — Early Impressions: Why JD and Will are both running it now and will report back once they have firsthand experience to share
You're a warrior. Act like one.
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Peptide Of The Week Website: https://peptideoftheweekpod.com
Join The Community: https://www.skool.com/peptideresearchinstitute/about
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Tim Elkins, JD's first mentor in business and now owner of Elkins Cattle Co., one of Texas's largest cattle operations spanning 40 to 50 thousand acres. This one is not about peptides. It is about what is actually in your food and why it matters just as much.
Chapters:00:00 – Intro00:13 – Meeting Tim Elkins01:36 – Tim's Background: Finance to Cattle Ranching07:53 – The Time Management Lesson That Changed JD's Career10:35 – Cattle Ranch to Table: How the Industry Really Works12:23 – The "Big Four" Monopoly Explained14:24 – Why Elkins Cattle Co Refuses to Cut Corners18:46 – The Truth About Foreign Beef21:00 – Why Ribeye Prices Doubled & Who Profits25:03 – Grocery Store Ground Beef: What's Really In It29:44 – What's Legal But Should Shock You34:29 – How to Tell a Cheated Steak From a Real One39:10 – The Truth About "Wagyu" Labels at Costco42:47 – Grass-Fed vs. Grain-Finished Explained47:26 – Inside a Feedlot: How They Track Every Animal54:08 – How Buying Local Can Starve Out the Big Four & Outro
We cover:🐄 How beef actually gets to your table– 90% of American beef passes through just four companies: JBS, Cargill, Tyson, and National Beef– These four have a stranglehold monopoly on the entire industry and prioritize speed and profit over quality– 70% of beef consumed in America is foreign beef. Most people have no idea– Animals are often slaughtered at under 12 months old or as old non-producing cows to cut costs– Horse meat in fast food chains: confirmed. And it is more widespread than just Taco Bell
🚫 What store-bought beef actually contains– Hormones, antibiotics, mRNA vaccines, and artificial additives are standard practice in commercial beef production– Wagyu labeling loophole: a product only needs 0.001% wagyu genetics to legally use the wagyu label. That ribeye at Costco is not what you think it is– "Grass-fed" on a label means almost nothing. Every cow has eaten at least one piece of grass. The label has no meaningful standard– Pink slime in ground beef is real and it comes from reputable-looking places, not just fast food– Veal in most restaurants is almost certainly a calf that died in transit or in a pen, not one that was intentionally raised for that purpose
🥩 What Elkins Cattle Co. does differently– Zero hormones, zero antibiotics, zero mRNA vaccines, zero shortcuts– All animals are 30 months old at slaughter, not 12 months– 40 to 50 thousand acres across Texas, nearly 9,000 head of cattle– Consumer direct: order by Monday, ships frozen to your door by Tuesday– Retina scanning technology tags every animal daily, tracking food intake, water, health markers, and time spent laying down. Red X spray marks any animal that needs attention that morning– Grass-fed AND grass-finished: fed four specific grasses including coastal Bermuda, Klein, native grasses, and winter oats to mimic the intramuscular fat quality of grain-finished beef without any GMO grain inputs– Animal welfare is non-negotiable: a stressed, unhappy cow does not gain weight properly and the difference shows up in the meat
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/
Follow Tim Elkins:Website: https://www.elkinscattleco.comX (Twitter): https://www.x.com/elkinscattlecoInstagram: https://www.instagram.com/elkinscattleco/
Join The Community: https://www.skool.com/peptideoftheweekcommunity
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham is joined by peptide consultant Michael Vandal and Nora Addam, wholesale director at Forge Biolabs, while Will enjoys Hawaii. They cover the new Warrior Maker Wellness Center, overtraining at 8% body fat, FOXO4-DRI vs fasting for autophagy, circadian rhythm eating for women, HGH for post-menopausal belly fat, and R maintenance dosing.
Chapters:00:00 – Intro & Meet the Co-Hosts02:28 – School Platform Update & Losing Social Media03:53 – Coaching Program Details04:43 – Warrior Maker Wellness Center Announcement09:55 – Q&A: Overtraining as a Firefighter at 8% Body Fat17:48 – Q&A: Ammonia Smell During HIIT on "R"22:35 – Q&A: Stubborn Belly Fat After Major Weight Loss29:42 – Q&A: High Inflammation Markers & Mitochondrial Peptides39:44 – Q&A: FOXO4-DRI, Epitalon & the Case for Fasting50:39 – Q&A: Getting Your Doctor to Optimize Your Hormones55:10 – Q&A: Urolithin A vs. SS-31 & MOTS-C59:33 – Q&A: Should You Stack "R" & Tirzepatide?1:03:34 – Q&A: Fatigue on "R" (Age 46)1:09:14 – Q&A: Longevity Peptides for Postmenopausal Women1:10:05 – Q&A: "R" Dosing Math & Maintenance vs. Cycling Off1:16:32 – Outro & Coaching Program Plug
We cover:• Warrior Maker Wellness Center is Coming: Hyperbaric chambers, red light, and longevity services dropping in downtown Huntington Beach and Warrior Makers supplements by Christmas• 8% Body Fat Firefighter Overtraining: Why a rest day is when you actually build muscle, why sleep and stress management matter more than adding compounds, and why fasting is JD's top add for lean men• MOTS-C Personal Experience When It Works and When It Doesn't: Why some people feel nothing on MOTS-C and why blood work and stool testing reveal more than any peptide response• FOXO4-DRI vs Fasting for Autophagy: Why JD prefers fasting over FOXO4 for senescent cell clearance, why a 72-hour fast quarterly may be the most powerful longevity tool available, and why Epithalon pairs perfectly with a four-week break• Fasting for Women Is Different: Nora's case for eating to your circadian rhythm, why skipping breakfast triggers thyroid issues in perimenopausal women, and why front-loading protein and calories changes everything• 47-Year-Old Female First Cycle Break Protocol: Why Epithalon for 10-20 days plus high-dose SS-31 is the ideal four-week reset, and why staying on glutathione through the break makes sense• Fatigue on R in Women: Why under-fueling is almost always the culprit, why MOTS-C was a game changer for Mike on R, and why glycine and magnesium glycinate are non-negotiable for sleep• Longevity Stack for Post-Menopausal Women at 55: Why HGH is the unanimous answer, why blood work including A1C and fasting insulin must come first, and why it targets belly fat specifically• R Maintenance vs Cycling Off at Goal Weight: Why 1 meg every five days is Mike's sweet spot, why JD believes building discipline off the compound matters just as much, and why both approaches are valid
You're a warrior. Act like one.
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
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Coaching Website: https://www.warrior-makerscoaching.com/

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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Liz Roman, owner of FitMom Functional Health, certified functional practitioner, co-host of The Health Revival Show, and the self-proclaimed (and trademarked) Poop Queen. If your gut is jacked, this episode is for you.
Chapters:00:00 – Intro & Meeting Liz "The Poop Queen"01:51 – Why Everyone's Gut Is Struggling Today07:09 – The Foundation: Diet, Hormones & Stress Come First08:59 – JD's Gut Story & Where to Start Healing13:13 – Stomach Acid: The Missing Domino15:39 – Order of Operations: Parasites, Detox & Ivermectin19:40 – Rapid Fire: What Should Poop Look Like?21:28 – Prebiotics vs. Probiotics vs. Postbiotics Explained26:39 – Junk Products & Peptide Scams to Avoid30:59 – Daily Habits: Eating & Bathroom Hygiene35:27 – Fasting & Protein Timing for Women40:11 – Decoding Chronic Bloating43:10 – Liz's Personal Health Journey46:57 – SIBO, Candida & the Real Role of Antibiotics52:07 – Liz's Favorite Peptides & Daily Supplement Stack
We cover:🦠 Why everyone's gut is a mess– Chronic stress, poor diet, COVID spike proteins, nutritional deficiencies, and environmental toxins are all converging at once– Spike proteins attach to mast cell receptors throughout the gut microbiome and cardiovascular system, shifting how the immune system behaves– Magnesium, B vitamins, and vitamin D deficiencies accelerated post-2020 and are still largely unaddressed– You will never out-supplement, out-peptide, or out-hormone a bad diet and poor stress management. Period.
🧬 The north-to-south digestion process– Stomach acid is the first domino. When it is low (from stress, aging, NSAIDs, medications, or past substance use), nothing downstream works properly– Stomach acid must be robust enough to emulsify protein into amino acids AND kill incoming parasites, pathogens, viruses, and bacteria– Always take betaine HCL in capsule form, never powder, the capsule protects it from being neutralized before it reaches the stomach– Low stomach acid fails to signal the pancreas, which then fails to release digestive enzymes, which then fails to signal the liver and gallbladder to release bile
🫐 Bile is the missing link nobody talks about– Bile is your internal built-in antimicrobial, circulating through the small intestine 15 to 17 times per meal– It is your body's natural defense against SIBO. When bile flow is compromised, bacteria overgrow where they should not be– The liver-gut axis is real, anatomically proven, and almost entirely ignored by conventional medicine– Supporting bile flow with things like TUDCA is essential, especially on GLP-1s and high-fat diets
🦠 SIBO, Candida, parasites, and the carnivore trap– Restrictive diets like carnivore can clear symptoms short term but also deprive gut bacteria of the fibers, polyphenols, and prebiotics they need to thrive– Parasite cleanses need to be a minimum of 45 to 60 days, not 7-day moon cycles. The parasite lifecycle is 45 to 60 days from egg to adult– Antibiotics take 6 months to 2 years to recover from after just one round. If you must take them, support the gut simultaneously
📺 Subscribe for more no-fluff peptide education every week.
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/
Follow Liz Roman:Website: https://fitmom.coFree Constipation Care Guide: https://fitmom.co/CCGInstagram: https://www.instagram.com/thepoopqueen/Podcast: The Health Revival Show
Join The Community: https://www.skool.com/peptideoftheweekcommunity
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover building muscle at 13.5% body fat, running carnivore diet on "R", St. John's Wort interactions, peptides for a marathon at 53, the mitochondrial stack sequenced properly, and whether IGF-1 LR3 and HGH can be run together.
Chapters:00:00 – Intro & Holiday Weekend Recap00:39 – Shark Stories & Ocean Safety Talk07:35 – School, Coaching & Warrior Maker Updates08:18 – Q&A: Muscle Gain & a Shredded Stomach (Age 43)15:11 – Q&A: R & Fat Digestion on Carnivore20:59 – Q&A: St. John's Wort & Peptide Interactions24:39 – Q&A: KPV for Connective Tissue Disease27:42 – Q&A: Low Energy on Tirzepatide & AOD (Age 38)36:05 – Q&A: How Long Do Unmixed Peptides Last?38:36 – Q&A: Do Peptides Show Up on Drug Tests?40:35 – Q&A: Stacking HGH, CJC/Ipa & IGF-1 LR347:36 – Q&A: Marathon Training Stack After Major Weight Loss51:40 – Q&A: Sequencing Mitochondrial Peptides for Energy (Age 55)56:53 – Outro & New Hyperbaric Chamber Announcement
We cover:• Building Muscle at 13.5% Body Fat as a Woman: Why eating more not less is the answer, why AOD should come out, and why 5-Amino-1-MQ, SLU-PP-332, and Tesamorelin-Ipa are the right additions
• Carnivore Diet on "R" with Ulcerative Colitis: Why high fat plus slow gastric emptying causes the problem, why small frequent meals fix it, and why a little fiber and 50 grams of carbs around training goes a long way
• St. John's Wort & "R" Interactions: Why R is broken down by protein enzymes not the liver's CYP450 system, why St. John's Wort is notorious for drug interactions, and why milk thistle, TUDCA, and glutathione are better liver support
• Mixed Connective Tissue Disease & KPV: Why oral BPC and KPV are generally safe to add, and why coming off a biologic requires a knowledgeable doctor not a podcast
• Low Energy on Tirzepatide at 133 Pounds: Why under-eating protein is the most likely culprit, why tracking macros is more powerful than any peptide, and why NAD, SS-31, MOTS-C, and methylated B12 are the right energy stack
• Lyophilized Peptide Shelf Life The Real Answer: Why unmixed peptides last up to two years in a cool dark place, why freezing creates moisture risk, and why the crisper drawer in a small fridge is all you need
• Do Peptides Show Up on a 5-Panel Drug Test: Why no standard workplace panel tests for peptides and why only high-level professional sports testing would even attempt it
• HGH vs IGF-1 LR3 — Can You Stack Both: Why CJC-Ipa is redundant once you're on HGH, when combining HGH and IGF-1 LR3 adds benefit vs. risk, and why MK-677 may be the smarter muscle-building add-on
• Marathon Prep Stack at 53 Down 87 Pounds: Why Wolverine is non-negotiable at this age and mileage, why Cardarine and SLU-PP-332 are the endurance game changers, and why adding HGH now gives it time to work before December
• Mitochondrial Stack for a 55-Year-Old Working at 2:30 AM: Why SS-31 comes first for at least two weeks, when to layer in MOTS-C, why NAD timing doesn't matter, and why Dihexa, magnesium glycinate, and glycine round out the protocol
You're a warrior. Act like one.
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Peptide Of The Week Website: https://peptideoftheweekpod.com
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Coaching Website: https://www.warrior-makerscoaching.com/

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas get back to basics and break down two compounds people have been asking about. ARA-290 for nerve pain and neuropathy, and 5-Amino-1MQ for fat burning and metabolic optimization. Two very different compounds with very different objectives.
Chapters:00:00 – Intro & Show Plugs02:37 – New Podcast Format Announcement03:28 – ARA-290: Redefining Nerve Pain & Repair05:09 – Nerve Injury Stories: Sciatica & Back Surgery08:03 – How ARA-290 Works: Macrophage Reprogramming13:15 – Dosing Protocols & Cost15:47 – Nerve Pain, Surgery & Long-Term Nerve Damage17:39 – Tips: Timing, Sleep, Nutrition & Exercise22:23 – Side Effects, Safety & What to Stack With24:59 – Compound #2: 5-Amino-1MQ for Fat Burning27:32 – Real User Results & Fat Loss Data30:00 – Dosing: Oral vs. Injectable & Cycle Length33:16 – Zone 2 Cardio & Maximizing Fat Burn37:37 – Stacking with GLP-1s & Breaking Plateaus40:49 – Outro, Feedback & Next Episode Preview
We cover:🧠 ARA-290 — Nerve Repair and Neuropathic Pain– First discovered and researched in the early 2000s, still experimental but with human trials– Selectively binds to the Tissue Protective Receptor (TPR) on immune cells, nerve cells, and metabolic tissues– Reprograms macrophages from pro-inflammatory to anti-inflammatory, actually healing the nerve instead of masking pain– Used for small fiber neuropathy, sarcoidosis, autoimmune nerve conditions, diabetic neuropathy, and post-viral recovery including long COVID– Unlike painkillers, effects continue AFTER you stop taking it because it is healing the nerve, not just covering the pain
Real-world reports:– Burning pain dropped from a 7 out of 10 to a 2 out of 10 within 3 weeks in diabetic neuropathy patients– Mood lift and mental calm reported within 4 days (not the main intention but consistently reported)– Nerve fiber density measurably increases over days to weeks– Effects often persist 3 to 6 months post-cycle
What to stack with:– BPC-157 and TB-500, NAD+, alpha lipoic acid, methylcobalamin, and B vitamins
What to avoid:– NSAIDs and corticosteroids will blunt the effects– Alcohol, high sugar, ultra-processed food, and chronic sleep deprivation all work against nerve healing
🔥 5-Amino-1MQ — The Fat Burning Compound– Not a peptide, technically a small molecule compound. First developed around 2014– Blocks NNMT (Nicotinamide N-Methyltransferase), which is massively upregulated in obese fat tissue and actively drives fat storage– Blocking NNMT shifts your metabolism to burn fat instead of store it, essentially injecting keto without the diet– Also replenishes NAD+ levels that have been depleted with age– In animal studies: obese mice lost 7 to 9% of fat with no loss of lean muscle while eating the same amount of food– Adds an additional 7 to 9% fat loss on top of GLP-1 results because it works on a completely different pathway
Who it is for:– Anyone on a GLP-1 who has plateaued, this will relight the fire– People with insulin resistance or pre-diabetes, it increases insulin sensitivity– Already lean people looking to get even leaner and enhance body composition– People with metabolic syndrome or NAD+ depletion
Best stacks: GLP-1 (especially R), MOTS-C, NMN, NAD+, L-Carnitine, Alpha Lipoic Acid, CoQ10
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/
Peptide Of The Week Website: https://peptideoftheweekpod.com/
Join The Community: https://www.skool.com/peptideoftheweekcommunity
Coaching Website: https://www.warrior-makerscoaching.com/

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover managing high hematocrit on TRT, why HDL drops on testosterone, navigating peptide social media censorship, peptide dosing math broken down simply, hair loss and DHT blockers, and protocols for insulin resistance and PCOS.
Chapters:00:00 – Intro & School Platform Update01:20 – Coaching Program Update & New Coaches03:48 – Website Launch & Losing Social Media Channels04:40 – Personal Life & Family Updates07:13 – Upcoming Hawaii Trip08:52 – Teaching Discipline: The Jax Story12:23 – Q&A: Managing High Hematocrit on TRT21:33 – Q&A: Insulin Resistance & Weight Loss28:24 – Q&A: Peptide Dosing Math Explained36:41 – Q&A: Navigating Social Media & Regulation44:29 – Q&A: Low HDL on TRT49:06 – Q&A: Adjusting Your Stack After Reaching Goal Weight58:35 – Q&A: Hair Loss & DHT Blockers on TRT1:07:24 – Q&A: Microplastics in Backwater Vials1:10:14 – Q&A: PCOS, ACL Recovery & Building Muscle & Outro
We cover:• High Hematocrit & Thick Blood on TRT: Why testosterone shuts off your body's governor on red blood cell production, why dehydration skews the reading, and why donating blood twice a year is the single best fix• Insulin Resistance & Slow Fat Loss in Women: Why cardio is making it worse, why 40 grams of protein right when you wake up matters, and why walking 10 minutes after every meal may do more than any peptide• Peptide Dosing Math Explained Simply: A live walkthrough of how to calculate exact milligrams per unit for GHK-CU, KPV, MOTS-C, C-Max, and "R" so nothing gets wasted• Navigating Social Media Censorship as a Peptide Educator: Why JD's YouTube got pulled for a 10-minute fasting post, why algorithms are replacing human judgment, and why School and owned platforms are the only safe play• Going Down on "R" After Reaching Goal Weight: Why 5 migs every two weeks makes no sense given the half-life, why 2-3x weekly dosing works better, and when to swap Tesamorelin for 2 IU of HGH• Low HDL on TRT — What Actually Helps: Why niacin has been proven not to work, why aromatase inhibitors make it worse, and why mono-unsaturated fats and fasting are the real levers• Hair Loss, DHT, Finasteride & Dutasteride: Why you're going to lose your hair if your family did regardless, why DHT blockers tank libido and mood, and Will's strategy of microdosing for 3 days to reset without the side effects• Plastic vs. Glass Bacteriostatic Water Vials: Why benzyl alcohol pulls microplastics from plastic vials over time and why glass is the cleaner long-term choice• 32-Year-Old Female with PCOS & ACL Tear: Why Tesamorelin-Ipa blend is the right starting point, why "R" at 500 mcg is virtually nothing, and why protein immediately after waking is non-negotiable
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Dani Carroll, a holistic health coach with 17 years of experience, Ayurvedic specialist, and yoga teacher. This one is not about peptides. It is about the thing most of us completely overlook that could be undermining everything else we do. Water.
Chapters:00:00 – Intro & Meeting Dani Carroll01:05 – Dani's Autoimmune Story & Failed Treatments07:00 – Discovering the Water That Changed Everything11:11 – First Results: Brain Fog, Joint Pain & Skin13:00 – Testing It on Her Skeptical Parents17:56 – Why Isn't Anyone Talking About Water?19:17 – The Truth About Tap & Bottled Water25:44 – How Bottled Water Degrades in Transit27:47 – RO & Distilled Water: The Mineral Problem29:46 – Understanding pH & the Alkaline Water Scam34:06 – JD's GERD & Gut Health Case Study41:19 – Chlorine, Showers & Skin Absorption50:04 – How the Machine's Settings & Hydrogen Water Work1:14:04 – Checking Your Own Tap Water (EWG Database)1:21:13 – Five Rules for Drinking Water & Outro
We cover:💧 Dani's story– Autoimmune disease surfaced at 16, misdiagnosed with rheumatoid arthritis, full body joint pain and monthly skin peeling episodes– Spent years going through every elimination diet, raw vegan, autoimmune paleo, nothing lasted beyond 90 days– Gut microbiome destroyed by antibiotics prescribed by doctors who never addressed the root cause– Discovered structured alkaline water during postpartum depression, within 45 days her skin stopped peeling for the first time in years– 90 days in she was glowing. Her father lost weight, eliminated gout, and cleared acid reflux within months
🧬 Why water matters more than food– You can survive 40 days without food. You die in 3 days without water. Yet nobody talks about water quality– Tap water contains chlorine, fluoride, heavy metals, pharmaceuticals, forever chemicals, pesticides, and herbicides– The chemicals in tap water are often added to protect aging city pipes, not to clean your water– Water softeners add salt or potassium to protect your pipes, they are not designed to be consumed– RO filtered water strips all minerals. Drinking it long term leaches minerals from your bones, causing bone density loss and eventually osteoporosis– Plastic bottled water is dead water that sits in your stomach, does not absorb properly, and leaches microplastics
🚿 Your shower is a bigger problem than you think– You absorb approximately one liter of water through your skin during a 10 to 15 minute hot shower– Pores open in hot water, you inhale chlorine vapor, and your body absorbs it all
The 7 pH settings explained:– 2.5 pH (hypochlorous acid): kills E. coli, MRSA, and bacteria. Use to sanitize meat, surfaces, and as mouthwash– 11.5 pH (strong alkaline): veggie wash, makeup remover, skin treatment, poison ivy compress, eczema protocol. Neutralizes pesticides and herbicides which are designed to be water resistant– 6.0 pH (beauty water): matches your skin and hair pH of 6.4. Use to wash your face and hair, works as a leave-in conditioner without stripping natural oils– 7.0 pH (neutral): neutral rinse water for cooking and final food rinse– 8.5, 9.0, 9.5 pH: drinking water levels depending on your health goals and tolerance
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/Coaching Website: https://www.warrior-makerscoaching.com/
Follow Dani Carroll:Instagram: https://www.instagram.com/rawsomeyoga/TikTok: https://www.tiktok.com/@rawsomeyoga
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover why SS-31 has been a game changer for JD, how to properly sequence the mitochondrial stack, NAD reactions and replacements, when to come off R, building muscle at 12% body fat, fertility protocols while on TRT, and whether you really need to plan your protocols a year in advance.
Chapters:00:00 – Intro & Personal Health Updates03:06 – SS-31 & Finding the Right Protocol06:04 – Disneyland Trip & Kids' Sports Talk13:48 – Warrior Makers Coaching Program Launch18:37 – School Platform Updates & Podcast Feedback21:58 – Q&A: Sleep, Hormones & Energy for a Busy Mum34:15 – Q&A: Major Weight Loss & a Bad NAD Reaction39:07 – Q&A: Peptide Storage & Condensation41:50 – Q&A: SS-31, MOTS-C & NAD Sequencing49:31 – Q&A: Coming Off Retatrutide's Maintenance Dose55:22 – Q&A: TRT & Fertility Protocols1:08:14 – Q&A: Gut Health Flare-Up & Peptide Pause1:14:53 – Q&A: Runner Wanting Muscle Over Fat Loss1:21:14 – Q&A: Building a Smart Annual Peptide Plan1:29:13 – Outro & Coaching Call Details
We cover:• Why JD Is Feeling the Best He Has in Years: Why higher-dose SS-31 gets the credit, why less compounds often means feeling better, and why starting with two compounds and adding slowly is the smarter approach• NAD Allergy What to Do Instead: Why reactions to NAD may come from the compound itself not just contamination, why SS-31 at five-plus megs is the closest alternative, and why blood work and hormone optimization should come first at 35• Peptide Storage and Condensation on Vials: Why condensation on the outside of a vial does not mean moisture got inside, and why a dedicated mini fridge beats any canister solution• Mitochondrial Stack SS-31, MOTS-C and NAD Sequenced Properly: Why SS-31 plugs the holes before MOTS-C revs the engine, why quarterly month-long SS-31 cycles make sense, and why NAD can run anytime regardless• 42-Year-Old Australian Female Should You Come Off R: Why she probably doesn't need it at all, why 5-Amino-1-MQ and SLU-PP-332 are the right replacements, and why discipline is a better long-term tool than any GLP• Fertility Protocol at 33 While Trying for a Baby: Why TRT doesn't have to stop, why HCG and Kisspeptin together improve fertility odds, and why Enclomiphene is the smarter choice over standard Clomid• Building Muscle at 12% Body Fat and Running 60-70 Miles a Week: Why all that running is burning off the muscle she's trying to build, why cutting back to HIIT and lifting heavy is the real answer, and why low-dose testosterone may matter more than any IGF-1• Total T of 420 at 43 Is It Time for TRT: Why 420 with low energy is answer enough, why TRT will change his life, and why planning protocols a full year out is overrated for most people• How to Build a Smart Annual Protocol Without Overcomplicating It: Why JD and Will plan four months at a time, why trying too many compounds at once tells you nothing, and why the gateway compounds R and BPC are always the right starting point
📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.
You're a warrior. Act like one.
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/
Coaching Website: https://www.warrior-makerscoaching.com/

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.