Podcast

Gladden Longevity Podcast

Alternative Health, Health & Fitness, Medicine

On this podcast focused on health and human longevity, Dr. Jeffrey R. Gladden, MD, FACC, examine the latest scientific research, technology, and biohacks to uncover the truth about the human body's potential for extending both life and health span well past what most people accept as biological facts.

Episodes
361
Releases
Weekly
Typical length
42 min
On air since
2017
Latest episode
5 days ago

Episodes

361 episodes, newest first

  1. The Future of Longevity: Purpose, Not Just Better Biomarkers - Episode 362

    Episode 362

    Show notes

    Dr. Gladden and Dr. Natasha Vita-More digs into the multifaceted aspects of longevity, memory, and the philosophical implications of living longer. They explore the evolution of perspectives on longevity, the intersection of technology and health, and the importance of integrating philosophical discussions into the longevity movement. Natasha shares her passion for life and the complexities of human existence, while also addressing the need to redefine death and consciousness in the context of advancing technology. The conversation emphasizes the importance of memory and the potential for human evolution as we navigate the future of longevity. In this conversation, Natasha Vita-More and Dr. Gladden delve into the themes of biostasis, spirituality, and the impact of social media on human behavior. They explore the disparity between technological advancement and human wisdom, the importance of self-worth in achieving longevity, and the psychological effects of tribalism and binary thinking. The discussion emphasizes the need for a movement towards a more enlightened understanding of human existence and the quest for meaning beyond superficial fame.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Natasha's journey into longevity began with a childhood fascination with life.

    · The longevity field has evolved from visionary ideas to a more conservative approach.

    · Longevity should focus on raising humanity rather than elitist practices.

    · The integration of technology and philosophy is crucial in the longevity discussion.

    · Memory plays a significant role in our understanding of life and death.

    · The future of human evolution is tied to our understanding of longevity.

    · Redefining death is essential as technology advances.

    · Aging should be viewed as a degeneration rather than wisdom.

    · The conversation around longevity needs to include critical thinking and philosophy.

    · Natasha's love for life drives her passion for exploring human evolution. Biostasis could revolutionize our understanding of longevity.

    · Spirituality plays a crucial role in how we perceive life and death.

    · Social media reflects our societal inadequacies and ignorance.

    · Tribalism and binary thinking hinder our progress as a society.

    · Self-worth is essential for feeling safe and secure in life.

    · We must remember our true selves to overcome trauma and societal pressures.

    · The quest for fame often distracts from genuine personal growth.

    · Creating a movement for change requires passionate individuals.

    · Understanding our psychological tells can help us improve our behavior.

    · We need to focus on wisdom gained from firsthand experiences.

    Chapters

    00:00 Introduction to Longevity and Memory Exploration

    03:03 The Evolution of Longevity Perspectives

    05:53 The Intersection of Longevity and Technology

    09:06 Philosophical Underpinnings of Longevity

    11:12 The Meaning of Life and Longevity

    15:08 The Future of Human Evolution

    17:55 Redefining Death and Consciousness

    21:01 The Role of Memory in Longevity

    24:10 Conclusion and Future Directions

    42:22 Exploring Biostasis and Longevity

    45:30 Spirituality vs. Materialism in Longevity

    48:01 The Impact of Social Media on Human Behavior

    51:07 Navigating Tribalism and Binary Thinking

    54:29 The Role of Self-Worth in Longevity

    57:43 Remembering Our True Selves

    01:01:18 The Quest for Meaning Beyond Fame

    01:05:05 Creating a Movement for Change To learn more about Dr. Natasha Vita-More:Website: https://www.natashavita-more.com

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    51 min
  2. From Illness to Insight: Stephen's Health Journey - Episode 361

    Episode 361

    Show notes

    Stephen Hussey shares his remarkable health journey, detailing his struggles with various inflammatory conditions from a young age, including asthma and type one diabetes. He discusses how lifestyle changes, particularly in diet, played a crucial role in managing his health. Despite leading a healthy lifestyle, Stephen experienced a widowmaker heart attack at the age of 34, which he describes in detail, including the symptoms and recovery process. He also explores the limitations of traditional medicine in predicting heart health risks and shares his decision to pursue alternative therapies post-heart attack, including the use of infrared sauna therapy. In this conversation, Dr. Gladden and Stephen Hussey explore the transformative journey of healing post-heart attack, emphasizing the importance of lifestyle changes, dietary adjustments, and the role of structured water in maintaining heart health. They discuss the significance of nitric oxide, the glycocalyx, and how structured water can enhance bodily functions. Stephen shares practical daily routines for optimizing structured water and the benefits of energized water, providing insights into how individuals can improve their health through natural means.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Stephen had multiple inflammatory conditions from a young age.

    · Diet changes significantly improved Stephen's health.

    · He pursued a career in chiropractic and nutrition after college.

    · Despite a healthy lifestyle, Stephen suffered a heart attack at 34.

    · Traditional medicine often fails to predict heart attack risks.

    · Stephen's heart attack was caused by an occluded artery.

    · He recovered well after the heart attack with minimal damage.

    · Stephen chose not to take certain medications post-heart attack.

    · He utilized infrared sauna therapy for heart health.

    · Lifestyle choices played a crucial role in Stephen's recovery. Stephen Hussey emphasizes the importance of a low-carb, animal-based diet post-heart attack.

    · Infrared sauna and sunlight exposure were key changes in Stephen's healing process.

    · Nitric oxide plays a crucial role in arterial health and healing.

    · The glycocalyx is essential for preventing plaque formation in arteries.

    · Structured water is vital for maintaining a healthy cardiovascular system.

    · Structured water creates a frictionless surface for blood flow.

    · Energy from the sun is crucial for building structured water in the body.

    · Daily practices can enhance structured water, even in winter.

    · Grounding and contact with the earth are important for health.

    · Energized water can be beneficial if it is toxin-free and mineral-rich.

    Chapters

    00:00 Stephen's Health Journey: From Childhood Illness to Heart Attack

    08:53 The Heart Attack Experience: Insights and Recovery

    16:52 Post-Heart Attack Choices: Alternative Therapies and Lifestyle Changes

    18:25 Healing Journey: Lifestyle Changes Post-Heart Attack

    21:04 The Role of Nitric Oxide and Glycocalyx in Heart Health

    23:59 Understanding Structured Water and Its Importance

    28:58 Daily Practices for Optimizing Structured Water

    34:09 The Science of Energized Water and Its Benefits To learn more about Dr. Stephen Hussey:Website: www.resourceyourhealth.com IG, FB, X, YT: @drstephenhussey

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    33 min
  3. Age Reversal, Cryonics, and the Biology of Life Extension - Episode 360

    Episode 360

    Show notes

    Dr. Gladden and Dr. Max More delve into the realms of transhumanism, life extension, and the philosophy of extropy. They explore the concept of cryonics and biostasis as potential solutions for achieving longevity, while also discussing the societal implications of AI and the search for meaning in an extended life. The dialogue emphasizes the importance of community, personal growth, and the challenges faced in the pursuit of a longer, healthier life. In this conversation, Dr. Gladden and Max More delve into the fascinating realms of age reversal, longevity practices, and the science of cryonics. They discuss the importance of diet, exercise, and sleep in maintaining health, while also addressing common misconceptions about cryonics. The conversation explores the techniques used in cryopreservation, the significance of memory retention, and the advancements in cooling methods that could revolutionize the field. Ultimately, they present a hopeful vision for the future of medicine and preservation.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Max More's interest in health began at a young age.

    · Life extension and biostasis are seen as viable options.

    · The definition of death is becoming increasingly complex.

    · Cryonics aims to preserve the brain's ultrastructure.

    · The philosophy of extropy encourages questioning limits.

    · AI's impact on work and society is a topic of concern.

    · Finding meaning in life is crucial for longevity.

    · Engagement in creative pursuits enhances life satisfaction.

    · Challenges are necessary for personal growth.

    · The Trim Trials show promising results in immune system rejuvenation. Age reversal techniques can yield significant results.

    · Maintaining a healthy lifestyle is crucial for longevity.

    · Cryonics is accessible and not just for the wealthy.

    · Preservation methods are based on scientific principles.

    · Memory retention in cryopreservation is a key area of research.

    · Rapid cooling techniques can enhance preservation outcomes.

    · Education about cryonics can dispel myths and misconceptions.

    · The future of medicine may include advanced preservation methods.

    · Understanding the science behind cryonics is essential for informed decisions.

    · Taking care of one's health is vital for optimal preservation.

    Chapters

    00:00 Introduction to Transhumanism and Life Extension

    03:06 Exploring Cryonics and Biostasis

    05:58 Philosophy of Extropy and Human Improvement

    09:08 The Role of AI and Future Work

    11:50 Finding Meaning and Purpose in Longevity

    15:01 Community and Collaboration in Transhumanism

    18:02 Challenges and Personal Growth in Longevity Research

    21:49 Exploring Age Reversal Techniques

    23:33 Foundations of Longevity: Diet, Exercise, and Sleep

    25:23 Understanding Cryonics: Myths and Realities

    27:58 The Science of Preservation: Techniques and Evidence

    31:07 Memory and Consciousness: Insights from Cryopreservation

    34:05 Rapid Cooling Techniques in Medicine

    39:11 The Future of Cryonics: A New Perspective To learn more about Dr. Max More:Website: https://www.maxmore.com/

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    35 min
  4. The Science Behind Aging and Rejuvenation - Episode 359

    Episode 359

    Show notes

    In this conversation, Dr. Gladden and Aubrey de Grey discuss the rapid advancements in the field of longevity research, emphasizing the importance of a systems biology approach to understanding aging. They explore the uneven distribution of funding and interest in various areas of research, the role of basic science, and the potential of stem cell therapies. The discussion highlights the need for a comprehensive strategy in addressing aging and the promising results from recent mouse trials. In this conversation, Aubrey de Grey discusses innovative approaches to senolytics and therapeutic combinations aimed at extending human lifespan. He emphasizes the importance of funding and research priorities in longevity, the role of AI in aging research, and the need to mobilize society against aging, drawing parallels to the COVID-19 pandemic. De Grey also elaborates on the hallmarks of aging and their implications for future research, while sharing his personal longevity strategies and practices.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · The longevity field is advancing rapidly with increased funding.

    · Interest in aging research is unevenly distributed.

    · A systems biology approach is essential for understanding aging.

    · Basic science is critical for developing effective interventions.

    · Stem cell therapies show promise in treating age-related diseases.

    · Rejuvenation should be viewed as an ongoing process.

    · Combining multiple interventions may yield better results.

    · Personalization of treatments is crucial for effectiveness.

    · Understanding the body's responses can lead to better outcomes.

    · Future trials will explore a wider range of interventions. We're using a vitaclax that is no longer toxic to platelets.

    · The new senolytic from Rockfish Bio shows promising results.

    · Our choices are focused on maximizing knowledge per dollar.

    · There's a lack of funding for comprehensive aging studies.

    · AI can provide insights but cannot replace clinical trials.

    · Mobilizing society is crucial to take aging seriously.

    · The hallmarks of aging classify downstream effects of damage.

    · Repairing damage is more effective than understanding its mechanisms.

    · Maintaining youthfulness is an ongoing process.

    · Regular health check-ups can identify personal weak links.

    Chapters

    00:00 The Current State of Longevity Research

    02:50 The Systems Biology Approach to Aging

    06:02 Understanding Aging: A Systems Perspective

    08:56 The Role of Basic Science in Longevity

    11:58 Interventions in Aging: Current Progress

    14:56 The Future of Stem Cell Therapies

    18:08 Rejuvenation as a Process

    21:01 The Divide and Conquer Strategy in Aging Research

    23:52 The Next Steps in Mouse Trials

    29:15 Innovative Approaches to Senolytics

    31:02 Exploring New Therapeutic Combinations

    32:36 Funding and Research Priorities in Longevity

    33:09 The Role of AI in Aging Research

    34:28 Mobilizing Society Against Aging

    39:26 The Hallmarks of Aging and Their Implications

    51:12 Personal Longevity Strategies and Practices To learn more about Dr. Aubrey De Grey:Website: https://www.levf.org/

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    47 min
  5. Mastering Memory Techniques with Ron White - Episode 358

    Episode 358

    Show notes

    In this episode of the Gladden Longevity Podcast, Dr. Gladden interviews memory expert and 2x USA Memory Champion, Ron White, who shares his journey into memory training and the techniques he uses to enhance memory. They discuss the mechanics of memory, the importance of repetition and review, and practical strategies for remembering names and information. Ron emphasizes the role of health, nutrition, and exercise in memory function and introduces the Mind Palace technique as a powerful tool for memory enhancement. In this conversation, Ron White discusses various memory techniques, particularly the mind palace method, and how he applies these strategies in memory competitions. He emphasizes the importance of visualization, emotional engagement, and understanding in the memorization process. The discussion also covers his preparation for the upcoming National Memory Championship, where he will face various challenges that test his memory skills. Throughout the conversation, the significance of making learning enjoyable and meaningful is highlighted.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Memory is not a gift; anyone can improve it.

    · Repetition is crucial for memory retention.

    · The forgetting curve shows how quickly we forget without review.

    · Recognizing information is the first step to recalling it.

    · Vivid and detailed mental images enhance memory.

    · Good nutrition and exercise support cognitive health.

    · Hearing impairment can affect memory and cognitive function.

    · Engaging all senses can improve memory retention.

    · The Mind Palace technique helps organize and recall information.

    · Creating stories around names can aid in remembering them. The mind palace technique allows for effective memorization.

    · Visualization enhances memory retention and understanding.

    · Emotional engagement can significantly improve memory recall.

    · Memory techniques can be applied in various contexts, including competitions.

    · Understanding the material is as important as memorizing it.

    · Creating associations can help in remembering complex information.

    · Repetition and review are crucial for long-term memory retention.

    · Using humor and creativity can aid in the memorization process.

    · Memory competitions test not only memory but also strategy and preparation.

    · Approaching memory challenges as a game can make the process more enjoyable.

    Chapters

    00:00 Introduction to Memory Mastery

    02:03 The Journey into Memory Training

    05:50 Understanding Memory Mechanics

    12:13 Practical Memory Techniques

    17:52 The Role of Health in Memory

    22:03 Exploring the Mind Palace Technique

    26:51 The Mind Palace Technique

    31:46 Memory Techniques for Competitions

    36:39 Visualization and Understanding in Memory

    40:49 Preparing for the National Memory Championship

    46:00 The Emotional Aspect of Memory To learn more about Ron White:Website: https://ronwhitetraining.com/

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    42 min
  6. The Metabolic Approach to Psychiatry - Episode 357

    Episode 357

    Show notes

    In this episode, Dr. Jeffrey Gladden and psychiatrist Dr. Matt Bernstein discuss the evolving landscape of mental health treatment. Bernstein shares his extensive experience in psychiatry, particularly with serious mental health conditions, and highlights the limitations of traditional medication approaches. He advocates for a more holistic view that considers metabolic health and mitochondrial function as critical components in understanding and treating mental health issues. The conversation also delves into the benefits of the ketogenic diet, cognitive flexibility, and the complexities of medication management in psychiatric care. In this conversation, Dr. Gladden and Matt Bernstein explore the intricate relationship between mental health, metabolism, exercise, and the role of psychedelics in therapy. They discuss the negative metabolic impacts of psychotropic medications, the significant benefits of exercise for mental health, and the importance of understanding individual genetics in managing depression. The conversation also delves into the role of lactate in brain health, mitochondrial function, and the potential of psychedelic therapies for personal transformation. Ultimately, they emphasize the need for a holistic approach to health that encompasses physical, mental, and spiritual well-being.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Matt Bernstein has 26 years of experience in psychiatry.

    · He works with serious mental health conditions like bipolar disorder and schizophrenia.

    · Traditional psychiatric medications often lead to metabolic and neurological side effects.

    · Anhedonia is a significant issue in mental health, meaning a lack of pleasure.

    · There is a need for a fresh perspective on mental health rooted in metabolism.

    · Mitochondrial dysfunction is linked to serious mental illnesses.

    · The ketogenic diet can be an effective intervention for mental health.

    · Cognitive flexibility is crucial for managing mental health conditions.

    · Medication management is complex and requires careful consideration.

    · Not all patients can or should stop their medications completely. Psychotropic medications can negatively impact metabolic health.

    · Exercise has a greater effect on depression than antidepressants.

    · Intense exercise is crucial for mental health benefits.

    · Genetics play a significant role in individual responses to depression.

    · Lactate production during exercise is beneficial for brain health.

    · Mitochondrial health is essential for longevity and mental well-being.

    · Stress affects both neurological and hormonal health.

    · Psychedelic therapies can provide transformative experiences for some individuals.

    · Social connectedness and purpose are vital for longevity.

    · Holistic approaches to health should integrate physical, mental, and spiritual aspects.

    Chapters

    00:00 Introduction to Mental Health Perspectives

    02:58 The Limitations of Traditional Psychiatry

    05:54 Exploring Root Causes in Mental Health

    09:05 The Role of Metabolism and Mitochondrial Function

    11:54 The Ketogenic Diet as a Therapeutic Approach

    14:59 Cognitive Flexibility and Mental Health

    17:56 Medication Management in Psychiatric Care

    23:24 Impact of Psychotropics on Metabolism

    24:49 The Role of Exercise in Mental Health

    27:53 Genetics and Personal Insights on Depression

    29:32 Lactate Production and Brain Health

    32:46 Mitochondrial Health and Longevity

    36:30 Mind-Body Connection and Stress Management

    39:08 Psychedelic-Assisted Therapies

    45:07 Optimizing Longevity and Health Span To learn more about Dr. Matt Bernstein:Website: www.accordmh.com LinkedIn: www.linkedin.com/in/mattbernsteinmd

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    43 min
  7. Dr. Jeffrey Gladden's Daily Longevity Routine: How He Trains for Strength, Mobility, and Energy - Episode 356

    Episode 356

    Show notes

    Dr. Jeffrey Gladden shares the full routine he uses to support longevity day to day, from his first hour in the morning to his weekly, monthly, and yearly training priorities. The episode is useful if you want a practical look at how he combines recovery, movement, therapy, and mindset to stay active and sharp.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    • In this episode, Dr. Gladden explains why he never wakes up to an alarm and instead lets his body set his sleep schedule.
    • He starts his day with thyroid medication, then uses the first 30 minutes for journaling, gratitude, daily goals, and affirmations.
    • He describes music as part of his routine, including picking up the guitar each morning to write, doodle, and release emotional energy.
    • He rotates his exercise instead of repeating the same workout daily, using mountain biking, running, elliptical work, and an elevation training mask to build lung capacity.
    • He emphasizes getting outside as often as possible and treating movement as a daily non-negotiable.
    • He stacks cardio with sauna when possible, often doing both before starting work.
    • He does not begin his workday until 10 a.m., using the morning to train, recover, and mentally prepare for clients and emails.
    • He trains mobility as seriously as cardio and resistance work, including floor work, crawling, burpees, and deep squat practice.
    • He mentions monthly therapies such as plasmapheresis, Eboo, red light, and ozone sauna as part of his longer-cycle routine.
    • He frames longevity as a yearly performance target: stronger, faster, fitter, sharper, and more mobile than the year before.
    • He stresses treating injuries immediately and using regenerative therapies and peptides to reduce downtime and slow the acceleration of aging.
    • He believes many people stop short in training and need to lean into hard effort rather than backing off too early.

    Chapters

    00:00 - Dr. Jeffrey Gladden's longevity philosophy and "100 is the new 30" 00:34 - Waking without an alarm and starting with thyroid medication 01:04 - Journaling, gratitude, goals, and affirmations to center the day 01:32 - Guitar, songwriting, and creative release as part of the morning 01:58 - Rotating cardio: mountain biking, running, elliptico, and lung capacity work 02:21 - Stacking sauna with cardio and why he delays the workday until 10 a.m. 02:57 - Why self-care comes before work performance 03:25 - Weekly training: resistance work, balance, crawling, burpees, and deep squats 03:54 - Building mobility through floor-based movement and outdoor activity 04:18 - Monthly therapies: plasmapheresis, Eboo, red light, and ozone sauna 04:54 - The yearly goal: outperform last year and treat injuries immediately 05:24 - Why aging requires different training strategies, including peptides 05:49 - Leaning into difficult workouts instead of backing off too early 06:19 - VO2 max testing, progress tracking, and listener call to action

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    7 min
  8. Navigating the World of 503A and 503B Pharmacies - Episode 355

    Show notes

    In this episode of the Gladden Longevity Podcast, Dr. Gladden hosts Joshua Fritzler, President of Olympia Pharmaceuticals, and Nicole Snow to discuss the intricacies of compounding pharmacies, focusing on the differences between 503A and 503B pharmacies, the role of compounding in personalized medicine, and the current landscape of peptides and FDA oversight. The conversation highlights the importance of safety, regulation, and quality assurance in compounded medications, providing listeners with a comprehensive understanding of how these pharmacies operate and their significance in modern healthcare.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Compounding pharmacies create personalized medications not commercially available.

    · 503A pharmacies serve individual patients with specific prescriptions.

    · 503B pharmacies produce larger batches for clinics and have stricter regulations.

    · Compounded medications can be tailored to avoid allergens or intolerances.

    · FDA does not approve compounded medications, but regulates the pharmacies.

    · Safety profiles of compounded medications are generally high when produced correctly.

    · Patients can request specific formulations that are not available commercially.

    · Compounding pharmacies must comply with state and federal regulations.

    · Quality assurance is critical in compounding, including testing for potency.

    · Understanding the differences between compounding pharmacies is essential for patients.

    Chapters

    00:00 Introduction to Compounding Pharmacies

    02:55 Understanding 503A and 503B Pharmacies

    05:56 The Role of Compounding in Personalized Medicine

    08:52 Safety and Regulation of Compounded Medications

    11:54 Differences Between 503A and 503B Pharmacies

    14:52 Navigating Prescription and State Regulations

    17:50 The Current Landscape of Peptides and FDA Oversight

    24:03 Quality Assurance in Compounding Pharmacies

    27:55 Conclusion and Future Directions

    55:52 A Call for a Manhattan Project in Chronic Disease Research

    To learn more about Joshua: Email: olympia@moburst.com Website: http://olympiapharmacy.com LinkedIn: https://www.linkedin.com/in/joshuafritzler/

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    27 min
  9. Preventing Heart Disease: A New Paradigm - Episode 354

    Episode 354

    Show notes

    In this conversation, Dr. Jeffrey Gladden and Dr. Philip Ovadia discuss the critical intersection of cardiology and longevity, emphasizing the need for a shift from treating heart disease to preventing it. They explore personal transformations, the role of diet, particularly low-carb and carnivore diets, and the importance of understanding insulin resistance in relation to heart health. The discussion also highlights advancements in cardiovascular diagnostics and the necessity for early detection and patient education to combat heart disease effectively.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · The focus on longevity in cardiology is essential.

    · Preventing heart disease is more effective than treating it.

    · Personal health transformations can lead to professional insights.

    · Dietary changes can significantly impact heart health.

    · Insulin resistance is a major factor in heart disease.

    · Understanding the role of cholesterol is crucial.

    · Early detection of insulin resistance can prevent heart disease.

    · Patient education is vital for long-term health outcomes.

    · Innovative diagnostics can revolutionize heart disease management.

    · A holistic approach to rehabilitation is necessary for recovery.

    Chapters

    00:00 Introduction to Longevity in Cardiology

    02:50 The Shift from Treatment to Prevention

    05:59 Personal Transformation and Dietary Changes

    08:58 Understanding Insulin Resistance and Heart Disease

    12:02 The Role of Diet in Cardiovascular Health

    15:07 Innovations in Cardiovascular Diagnostics

    18:02 The Importance of Early Detection

    20:56 Rehabilitation and Patient Education

    24:07 The Future of Cardiology and Preventative Care

    To learn more about Dr. Philip Ovadia: Facebook: https://www.facebook.com/ovadiahearthealth Instagram: https://www.instagram.com/ifixhearts/ Twitter: https://twitter.com/ifixhearts X URL: https://x.com/ifixhearts YouTube: https://www.youtube.com/@IFixHearts LinkedIn: Linkedin.com/in/philip-ovadia-heart-health/ Book: https://www.amazon.com/Stay-off-Operating-Table-Metabolic/dp/1737818205/

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    33 min
  10. Unraveling Alzheimer's: The Pathobiome Connection - Episode 353

    Episode 353

    Show notes

    Dr. Gladden and Nikki Schultek explore the intricate links between Alzheimer's disease, infections, and the pathobiome. Nikki shares her personal journey through chronic illness and how it led her to advocate for a better understanding of the role of infections in autoimmune and neurodegenerative diseases. They discuss the importance of a systems biology approach to healthcare, emphasizing the need for collaboration among specialists to address complex health issues. The conversation highlights the interplay between genetics, infections, and chronic diseases, and the potential for future research to uncover new treatment avenues. In this conversation, Dr. Gladden and Nikki Schultek discuss the integration of systems biology in health optimization, emphasizing the importance of collaboration in research and the role of AI in uncovering health insights. They explore the microbiome's impact on neurodegenerative diseases, hormonal influences on aging, and the necessity of a strong therapeutic connection in patient care. The discussion also touches on economic incentives in healthcare and the urgent need for a comprehensive approach to chronic disease research, likening it to a Manhattan Project.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Nikki's journey into the world of Alzheimer's began with her own health struggles.

    · Infections can drive autoimmune states and neurodegenerative diseases.

    · The medical system often operates in silos, complicating patient care.

    · Chronic infections may be overlooked in patients with complex symptoms.

    · A systems biology approach is essential for understanding chronic diseases.

    · Genetics and the pathobiome are interconnected in disease development.

    · Certain infections are linked to both heart disease and Alzheimer's.

    · Advocacy and collaboration are crucial for advancing research.

    · Lifestyle factors play a significant role in chronic disease prevention.

    · Future research should focus on the interplay between infections and chronic diseases. A systems biology approach can optimize health outcomes.

    · Collaboration in research is essential for progress.

    · AI can provide insights into complex health issues.

    · The microbiome plays a crucial role in neurodegenerative diseases.

    · Hormonal changes significantly affect aging and health.

    · Therapeutic connections between patients and providers are vital.

    · Economic incentives often misalign with health outcomes.

    · A comprehensive approach to chronic disease is necessary.

    · Existing solutions can be leveraged for better health.

    · Innovation in healthcare is accelerating rapidly.

    Chapters

    00:00 Introduction to Alzheimer's and Pathobiome

    04:59 Personal Journey: From Illness to Advocacy

    10:04 The Role of Infections in Chronic Diseases

    15:00 Exploring the Connection Between Heart Disease and Alzheimer's

    20:03 Genetics and the Pathobiome: A Complex Relationship

    25:03 The Importance of a Systems Biology Approach

    30:08 Future Directions in Research and Treatment

    30:38 Integrating Systems Biology in Health Optimization

    32:25 Collaborative Research and Team Science

    34:34 Leveraging AI for Health Insights

    36:20 The Role of the Microbiome in Neurodegenerative Diseases

    38:21 Hormonal Influences on Aging and Neurodegeneration

    40:44 The Therapeutic Connection in Patient Care

    42:49 Economic Incentives in Healthcare and Innovation

    55:52 A Call for a Manhattan Project in Chronic Disease Research

    To learn more about Nikki Schultek: Website: https://www.alzpi.org/ and https://www.intracellresearchgroup.com/ Instagram: https://www.instagram.com/nikki_schultek/ LinkedIn: https://www.linkedin.com/in/nikki-schultek-03634887/

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    59 min
  11. From Reactive Care to Preventive Longevity - Episode 352

    Episode 352

    Show notes

    In this episode, Dr. Gladden speaks with Dr. Hany Demian about the shift from reactive medicine to prevention, personalization, and longevity-focused care. Dr. Hany shares how his journey through breast surgery, emergency medicine, and chronic pain management led him to a more systems-based approach to health, aging, and healing. They discuss why aging may be better understood as a condition, how patient empowerment changes outcomes, and why nervous system regulation, stress reduction, and individualized care matter as much as diagnostics and therapies.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Dr. Hany says many chronic conditions are the result of biology drifting over time, not just isolated bad luck

    · He emphasizes that healthy patients are rarely rewarded in the current billing system

    · His approach is to assess where a patient's biology is now and how far it has diverged from a healthier baseline

    · Lifestyle foundations like sleep, nutrition, exercise, and supplements are treated as the first levers

    · Dr. Hany believes aging should be classified as a diagnosable, measurable condition

    · He points to hallmarks of aging, mitochondrial dysfunction, and epigenetic disruption as actionable signals

    · The conversation frames aging as something that can potentially be slowed, prevented, or reversed

    · Dr. Gladden discusses the limits of siloed, specialty-based care and linear thinking in medicine

    · Both speakers favor a systems biology model that looks at the whole person

    · The idea is to find not just the root cause, but the root cause of the root cause

    · Dr. Hany says the longevity field can become overly commercialized and supplement-heavy

    · He prefers a science-based, selective approach rather than flooding patients with interventions

    · The goal is to help the body restore itself with the right support

    · He describes building AI tools that track patients through wearables 24/7

    · His team combines genetic testing, ongoing data collection, and clinical interpretation

    · The aim is to predict future health trajectories and intervene earlier

    · Dr. Hany explains that not everyone is a fit for a longevity program

    · Patients must qualify, understand the plan, and commit to the process

    · He sees the best outcomes when patients become active partners in their care

    · Dr. Gladden emphasizes that the nervous system shapes aging, inflammation, cognition, and resilience

    · The episode explores parasympathetic versus sympathetic states and the value of flow over chronic stress

    · Both speakers agree that unresolved trauma and emotional strain affect physical health

    · Dr. Gladden shares how forgiveness can reduce psychic strain and support healing

    · Dr. Hany reflects on the difference between being successful and feeling fulfilled

    · They both highlight service, courage, and purpose as central to a meaningful life

    Chapters

    00:00 - Welcome and the shift from reactive to preventive medicine 01:11 - Breast cancer, family motivation, and the limits of surgery 03:56 - Why personalized medicine starts with biology, not billing 05:24 - Sleep, nutrition, exercise, and supplements as prevention tools 06:33 - Aging hallmarks and why aging may be a condition 08:40 - Reductionist medicine versus systems biology 11:23 - Why the longevity field needs standards and science 14:56 - Patient selection, trust, and individualized care plans 16:25 - Patients as partners, not passive recipients 19:54 - Longevity as adding life to years, not just years to life 20:22 - Stem cells, MSCs, peptides, exosomes, and plasma exchange 21:50 - Brain health, heart health, and musculoskeletal care 22:48 - AI, wearables, and real-time patient monitoring 25:20 - Predicting health five, ten, and fifteen years ahead 26:53 - The nervous system, stress, and psycho-spiritual health 30:25 - Teaching people to live from parasympathetic flow 33:24 - Forgiveness, psychic barriers, and emotional healing 35:42 - Why psychological health improves regenerative outcomes 36:22 - Finding purpose after success 39:15 - Success versus fulfillment 41:17 - Small daily acts of generosity as a path to joy To learn more about Dr. Hany Demian:Website: https://drdemian.com/ Instagram: https://www.instagram.com/drhanydemian/ LinkedIn: https://www.linkedin.com/in/hany-demian-md-5b79b659/ YouTube: https://www.youtube.com/@drhanydemain TikTok: https://www.tiktok.com/@dochanydemian

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    42 min
  12. The Exponential Curve of Aging - Episode 351

    Episode 351

    Show notes

    Michael Clinton and Dr. Gladden explore the concept of longevity and the evolving perception of aging. They discuss the importance of viewing the second half of life as an opportunity for growth and adventure rather than a decline. The discussion covers the significance of role models, the idea of life layering to build identities beyond work, the necessity of movement and engagement, and the architectural approach to health through five circles. They also touch on the generational transfer of health and the importance of community and connection in combating loneliness and mental health issues. In this conversation, Michael Clinton and Dr. Gladden explore the interconnected themes of community support, generational trauma, the impact of aging, and the power of creativity. They discuss how understanding one's family history can help in addressing mental health issues and the importance of embracing aging positively. The dialogue emphasizes the significance of co-creation and friendships across generations, highlighting how these relationships can enhance joy and fulfillment in life.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · We're living 21st century lives in 20th century constructs.

    · Aging is an exponential decline, not a linear decline.

    · If you're 65 and healthy, you're gonna live to 95.

    · Life layering is building another identity beyond profession.

    · The number one natural medicine is movement.

    · You can start life layering at any age.

    · Generational transfer of health is crucial for longevity.

    · Community ensures that the elderly have daily human contact.

    · Loneliness and depression are closely linked.

    · Living life in flow can reduce stress and loneliness. We need to look out for each other regarding mental health.

    · Understanding genetics can help us support individuals better.

    · Generational trauma can affect our mental health and well-being.

    · Knowing your family history is crucial for personal growth.

    · Trauma can imprint on our nervous systems and affect our lives.

    · Aging should be embraced, not feared or stigmatized.

    · Creativity can enhance longevity and well-being.

    · Co-creation with others brings joy and satisfaction.

    · Friendships across generations enrich our lives.

    · The narrative around aging is changing, and we must adapt.

    Chapters

    00:00 Roaring into the Second Half of Life

    02:50 The Exponential Curve of Aging and Opportunities

    05:48 Role Models for Future Generations

    09:01 Life Layering: Building Identities Beyond Work

    12:06 The Importance of Movement and Engagement

    15:09 Architecting Longevity: Five Circles of Health

    18:05 Generational Health Transfer and Future Longevity

    21:14 Community, Connection, and Loneliness

    24:01 The Intersection of Loneliness and Mental Health

    25:08 Understanding Generational Trauma

    26:27 The Impact of Trauma on Health

    28:40 Embracing Aging and Wisdom

    30:34 Redefining Aging in Society

    32:02 The Power of Creativity for Longevity

    36:41 The Joy of Co-Creation and Friendship

    To learn more about Michael Clinton:Email: mclinton@hearst.com

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    40 min
  13. Unlocking the Secrets of Nutrigenomics - Episode 350

    Episode 350

    Show notes

    In this conversation, Dr. Gladden and Annelie Smith explore the intersection of genetics and nutrition, emphasizing the importance of personalized approaches to health. They discuss the evolution of nutrigenomics, the role of AI in developing tailored health plans, and the complexities of hormonal balance as influenced by genetics. Annelie shares insights from her clinical experience, highlighting the need for a systems biology approach to understand the intricate relationships between genes, hormones, and overall health. The discussion also touches on future directions in genetic testing and the potential for more accessible and actionable insights for individuals. In this conversation, Dr. Gladden and Annelie Smith delve into the complexities of hormone replacement therapy, emphasizing the importance of understanding hormonal pathways and the role of genetics. They discuss how stress impacts hormonal balance and the significance of reprogramming the nervous system for better health outcomes. The conversation also highlights the relevance of nutrigenomics in personalized nutrition and the powerful benefits of sulforaphane. Finally, they explore the value of genetic testing for optimizing health and wellness.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Use the code GLADDEN20 for $20 off at https://3x4genetics.com/pages/gladden !

    Takeaways

    · Nutrigenomics provides insights into personalized nutrition.

    · Understanding genetics can enhance dietary recommendations.

    · AI is transforming the landscape of personalized medicine.

    · Systems biology offers a holistic view of health.

    · Patient engagement is key to successful health interventions.

    · Genetic testing can reveal vulnerabilities in health.

    · Hormonal balance is influenced by genetic factors.

    · Personalized health plans can improve patient outcomes.

    · The future of genetics holds promise for broader applications.

    · Access to genetic information can empower individuals. Hormone replacement therapy is complex and requires a systems approach.

    · Understanding genetic pathways is crucial for effective hormone management.

    · Stress significantly impacts hormonal balance and overall health.

    · Reprogramming the nervous system can alleviate stress and improve health.

    · Nutrigenomics plays a vital role in personalized nutrition.

    · Sulforaphane is a powerful compound with numerous health benefits.

    · Diet should be tailored to the individual, not a one-size-fits-all approach.

    · Genetic testing provides valuable insights for health optimization.

    · Managing stress involves rebuilding mental constructs that generate it.

    · Investing in genetic testing is a one-time opportunity with lasting benefits.

    Chapters

    00:00 Introduction to Nutrigenomics and Personalization

    02:49 The Role of Genetics in Nutrition

    06:01 Systems Biology Approach to Health

    08:55 AI in Nutrigenomics and Personalized Medicine

    11:51 Case Study: Hormonal Balance and Genetics

    14:59 Future Directions in Genetics and Health

    23:35 Understanding Hormone Replacement Therapy

    26:16 The Complexity of Hormonal Pathways

    28:26 The Role of Stress in Hormonal Balance

    30:22 Reprogramming the Nervous System

    32:37 Nutrigenomics and Personalized Nutrition

    36:27 The Power of Sulforaphane

    39:04 Exploring Genetic Testing for Health Optimization

    To learn more about Annelie Smith:Email: annelie@3X4.io Website: www.3X4Genetics.com

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    44 min
  14. The Microbial Connection to Autoimmunity - Episode 349

    Episode 349

    Show notes

    In this episode of the Gladden Longevity Podcast, Dr. Gladden interviews Dr. Bill Rawls, who shares his transformative journey from conventional medicine to holistic healing. Bill discusses his struggles with chronic illness, particularly Lyme disease, and how he discovered the importance of cellular health and autophagy in recovery. He emphasizes the role of herbal therapies and adaptogens in promoting wellness and protecting cellular function, ultimately leading to a deeper understanding of chronic illness and aging. In this conversation, they explore the intricate connections between autoimmunity, chronic illness, and the role of microbial influences. They discuss the implications of long COVID, the benefits of adaptogenic herbs, and the importance of nervous system regulation in healing. The conversation emphasizes the need for a holistic approach to health, focusing on creating a supportive environment for healing and the potential of herbal medicine in managing chronic conditions.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Dr. Bill Rawls transitioned from conventional medicine to holistic healing due to personal health struggles.

    · Chronic Lyme disease was a pivotal point in Dr. Bill's journey, leading him to explore alternative therapies.

    · Understanding cellular health is crucial for addressing chronic illnesses.

    · Autophagy is a key process for cellular rejuvenation and health.

    · Herbal therapies can effectively support the body's healing processes.

    · Adaptogens help the body adapt to stress and promote resilience.

    · Impaired autophagy is linked to many chronic illnesses.

    · Dr. Bill emphasizes the importance of diet, sleep, and lifestyle in maintaining health.

    · Herbs can protect cells from stress and inflammation.

    · The journey of healing is often non-linear and requires exploration of various therapies. Autoimmunity may be driven by microbial invasion and immune response.

    · Long COVID symptoms could be linked to reactivation of dormant pathogens.

    · Adaptogenic herbs can support cellular health and stress management.

    · Nervous system regulation is crucial for effective healing.

    · Herbal preparations can be more effective than traditional medications.

    · Creating a healthy environment is essential for chronic illness management.

    · The body's stress response can exacerbate chronic health issues.

    · Herbs can provide a broad spectrum of benefits beyond just antimicrobial effects.

    · Education and environment play key roles in health improvement.

    · Chronic illness management requires a shift in healthcare focus.

    Chapters

    00:00 Dr. Bill Rawls' Journey from Conventional Medicine to Holistic Healing

    05:12 Understanding Lyme Disease and Chronic Illness

    10:46 The Role of Autophagy in Health and Disease

    16:36 Herbal Therapies and Adaptogens in Healing

    25:20 Protecting Cellular Health and Mitochondrial Function

    26:20 Understanding Autoimmunity and Microbial Influence

    28:02 Long COVID and Chronic Illness Connections

    30:14 The Role of Adaptogenic Herbs in Healing

    32:07 Nervous System Regulation and Healing

    33:55 Herbal Preparations and Their Efficacy

    37:54 The Broad Spectrum of Herbal Medicine

    40:59 Creating a Healthy Environment for Healing

    49:03 The Future of Health and Chronic Illness Management

    To learn more about Dr. Bill Rawls:Facebook: https://www.facebook.com/rawlsmd/ Website: rawlsmd.com Instagram: https://www.instagram.com/rawlsmd/

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    51 min
  15. The Cost-Effectiveness of Compounding Pharmacies - Episode 348

    Episode 348

    Show notes

    In this episode of the Gladden Longevity podcast, Dr. Gladden interviews Shaun Noorian from Empower Pharmacy, discussing the growth and mission of the pharmacy, the cost-effectiveness of compounding medications, quality standards in compounding, regulatory oversight, and the ongoing controversy surrounding peptides and FDA decisions. The conversation highlights the importance of personalized medicine and the challenges faced by compounding pharmacies in providing affordable and effective treatments for patients. In this conversation, Dr. Gladden and Shaun Noorian discuss the evolving landscape of compounding pharmacies and personalized medicine. They explore the regulatory challenges faced by compounding pharmacies, the promise of new medications like retatrutide, and the role of GLP-1s in health management. The discussion highlights the importance of muscle preservation in weight loss therapies and the advocacy needed to ensure patient access to compounded medications. They emphasize the renaissance of compounding in healthcare, which is making treatments more accessible and affordable for patients.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Empower Pharmacy has been operational for 17 years and focuses on personalized medicine.

    · Compounding pharmacies are becoming more popular due to their cost-effectiveness compared to commercial options.

    · Quality standards in compounding are well-established and continuously updated.

    · Compounding pharmacies are subject to rigorous regulatory oversight and inspections.

    · The FDA is currently reviewing the status of several peptides for compounding.

    · Recent changes in the FDA advisory committee may impact the approval of new compounds.

    · The conversation emphasizes the need for evidence-based decisions in healthcare.

    · Dr. Gladden highlights the discrepancies in drug approvals and their implications for patient care.

    · The black market for peptides poses significant risks to patient safety.

    · The discussion underscores the importance of maintaining high-quality standards in compounding pharmacies. The FDA's decisions will significantly impact compounding pharmacies.

    · Compounding pharmacies ensure medication integrity and safety.

    · Personalized medicine is expanding into various health areas.

    · Regulatory challenges hinder the compounding of certain medications.

    · Retatrutide is expected to revolutionize weight loss therapies.

    · GLP-1s have multiple health benefits beyond weight loss.

    · Weight loss therapies can lead to muscle loss, complicating health outcomes.

    · Innovative alternatives to GLP-1s are emerging in the market.

    · Compounding pharmacies play a crucial role in patient access to medications.

    · Advocacy against pharmaceutical monopolies is essential for patient care.

    Chapters

    00:00 Empower Pharmacy's Growth and Mission

    03:01 Cost-Effectiveness of Compounding Pharmacies

    06:00 Quality Standards in Compounding

    08:54 Regulatory Oversight and Compliance

    12:01 The Peptide Controversy

    15:03 The Impact of FDA Decisions on Patient Care

    18:21 The Future of Compounding Pharmacies

    20:09 Expanding Areas of Personalized Medicine

    21:11 Regulatory Challenges in Compounding

    22:04 The Promise of Retatrutid

    23:39 The Role of GLP-1s in Health

    25:02 The Impact of Weight Loss Therapies

    26:07 Innovative Alternatives to GLP-1s

    27:10 The Importance of Muscle Preservation

    28:31 The Role of Compounding Pharmacies in Patient Access

    30:16 Advocacy Against Pharmaceutical Monopolies

    32:20 Navigating Regulatory Landscapes

    34:14 The Renaissance of Compounding in Healthcare

    To learn more about Shaun Noorian:Email: media@Empowerpharmacy.com Website: https://www.empowerpharmacy.com/ Instagram: https://www.instagram.com/empowerpharmacy

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    33 min
  16. The Future of Regenerative Joint Repair - Episode 347

    Episode 347

    Show notes

    In this episode, Dr. Marc Pietropaoli discusses his transition from traditional orthopedics to regenerative medicine, emphasizing the importance of repairing rather than replacing damaged joints. He shares insights on the components and sequencing of regenerative treatments, the role of genetic testing in nutrition, and his mission to eliminate the need for knee replacements by 2043. The conversation highlights the significance of prevention and proactive care in joint health. In this conversation, Dr. Marc Pietropaoli discusses various aspects of injury prevention, particularly focusing on ACL injuries and innovative surgical techniques. He emphasizes the importance of proper landing techniques, dynamic warm-ups, and the role of proprioception in preventing injuries. The discussion also covers the advancements in ACL repair, including the bear procedure, which utilizes a collagen implant to enhance healing and reduce the risk of arthritis. The conversation concludes with resources for further learning and insights into the future of sports medicine.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    • Dr. Pietropaoli transitioned from traditional orthopedics to regenerative medicine.
    • He emphasizes the body's ability to heal itself through regenerative techniques.
    • The importance of asking questions in medical training is highlighted.
    • Dr. Pietropaoli's personal experiences influenced his career path.
    • He advocates for a team approach in patient care, involving various specialists.
    • Inflammation is a key factor in joint health and must be addressed.
    • Genetic testing can guide nutritional choices for better health outcomes.
    • Preventive measures can significantly reduce the risk of joint injuries.
    • Dr. Pietropaoli aims to end the need for knee replacements by 2043.
    • The conversation underscores the importance of patient education in exploring treatment options. Bending knees during landing reduces injury risk.
    • Proper proprioception is crucial for athletes.
    • Dynamic warm-ups are more effective than static stretching.
    • Mastering two-legged exercises is essential before progressing to one-legged ones.
    • Plyometrics enhance fast twitch muscle fiber development.
    • Agility is linked to balance and quickness.
    • Bear surgery offers a promising alternative to traditional ACL repair.
    • Collagen implants can significantly aid in ACL healing.
    • Using blood flow restriction can enhance recovery post-surgery.
    • Education and awareness are key in sports injury prevention.

    Chapters

    00:00 Introduction to Regenerative Orthopedics

    04:08 The Journey from Traditional to Regenerative Medicine

    13:46 Components and Sequencing in Regenerative Treatments

    20:04 Genetic Testing and Nutrition for Optimal Health

    22:52 Future Aspirations in Joint Health and Prevention

    27:09 Injury Prevention Techniques

    34:06 Understanding ACL Injuries and Repair

    42:35 Innovations in ACL Surgery

    45:34 Resources and Final Thoughts

    To learn more about Dr. Marc: Website: www.victoryinmotion.com

    TikTok: https://www.tiktok.com/@drmarcpietropaoli

    Instagram: https://www.instagram.com/drmarcpietropaoli

    LinkedIn: https://www.linkedin.com/in/drmarcpietropaoli

    YouTube: https://www.youtube.com/@victoryinmotion1

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    43 min
  17. The Evolution of Orthopedic Techniques - Episode 346

    Episode 346

    Show notes

    In this conversation, Dr. Kevin R. Stone discusses his journey and innovations in cartilage regeneration, focusing on the importance of mindset, the role of anabolic therapies, and the significance of play in recovery and longevity. He emphasizes the need for a holistic approach to injury prevention and recovery, encouraging patients to view their injuries as opportunities for improvement rather than setbacks.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Kevin Stone's journey into cartilage regeneration began with a mentor's challenge.

    · The importance of finding materials that are both soft and durable for cartilage repair.

    · Articular cartilage and meniscus cartilage serve different functions in the knee.

    · Anabolic therapies are now being integrated into cartilage regeneration techniques.

    · The ankle joint presents unique challenges and opportunities for cartilage repair.

    · Mental errors are the leading cause of sports injuries.

    · Patients should view injuries as opportunities to improve fitness and strength.

    · The role of play is crucial in maintaining a youthful mindset and engagement with life.

    · Research into birth tissues may unlock new regenerative therapies.

    · Optimizing recovery involves a combination of physical therapy, nutrition, and mindset.

    Chapters

    00:00 Introduction to Cartilage Regeneration

    02:50 The Journey of Cartilage Repair Techniques

    06:00 Understanding Cartilage Types and Repair Methods

    09:05 Anabolic Approaches in Sports Medicine

    12:08 Expanding Techniques Beyond the Knee

    15:05 Risks and Complications in Cartilage Surgery

    18:01 The Importance of Mindset in Injury Prevention

    21:03 Optimizing Recovery and Performance

    23:55 The Role of Play in Longevity

    26:51 Future Directions in Cartilage Research

    To learn more about Dr. Kevin Stone: Website: https://www.stoneclinic.com Instagram: https://www.instagram.com/stoneclinic/

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    31 min
  18. Spermidine: The Key to Aging Gracefully - Episode 345

    Episode 345

    Show notes

    In this episode of the Gladden Longevity Podcast, Dr. Gladden and Leslie Kenny delve into the intricacies of aging, health, and the role of spermidine in promoting longevity. They discuss the hallmarks of aging, Leslie's personal journey with autoimmune conditions, and the importance of empowerment and curiosity in health management. The conversation emphasizes the interconnectedness of health factors and the need for a holistic approach to wellness. In this conversation, Leslie Kenny and Dr. Gladden explore the potential of spermidine as a breakthrough in aging research, discussing its effects on health, longevity, and cellular processes like autophagy. They share personal experiences with spermidine, the challenges of clinical research, and the importance of redefining aging. The conversation also highlights resources for healthy aging and the significance of mindset in health management.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/! Use code GLADDENLONGEVITYPOD to get 20% OFF on any of Leslie's supplements at https://oxfordhealthspan.com!

    Takeaways

    · Spermidine positively impacts multiple hallmarks of aging.

    · Crosstalk between hallmarks of aging can enhance health.

    · Mindset plays a crucial role in health outcomes.

    · Patients should collaborate with their healthcare providers.

    · Curiosity in medicine leads to better patient outcomes.

    · The healthcare system often lacks time for curiosity.

    · Empowerment in health management is essential.

    · Modulating the immune system can restore balance.

    · Personal experiences can lead to significant health insights.

    · Holistic approaches to health can yield better results. Spermidine activates autophagy, aiding in cellular renewal.

    · Chronic management of illnesses is not desirable; patients want solutions.

    · Biological age can be significantly lower than chronological age.

    · Spermidine has potential benefits for heart health and cognition.

    · Personal experiences with spermidine show promising results in sleep quality.

    · Clinical trials for food-derived compounds face financial challenges.

    · The body can adapt and respond positively to the right inputs.

    · Redefining aging is crucial for a healthier future.

    · Mindset plays a vital role in health and aging.

    · Resources like Oxford Health Span can provide valuable information.

    Chapters

    00:00 Introduction to Longevity and Health

    05:23 The Role of Spermidine in Aging

    08:52 Personal Journey with Autoimmune Conditions

    12:34 Empowerment in Health Management

    18:07 The Importance of Curiosity in Medicine

    25:21 Finding Balance in Immune Health

    31:32 The Quest for Longevity and Health

    34:58 Spermidine: A Breakthrough in Aging Research

    39:14 Personal Experience with Spermidine

    44:40 Challenges in Clinical Research

    49:52 Redefining Aging and Health

    52:52 Resources for Healthy Aging

    To learn more about Leslie Kenny: Instagram: https://www.instagram.com/lesliesnewprime/ Website: oxfordhealthspan.com, lesliesnewprime.com

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    50 min
  19. Combating Lyme, Detoxification, and Lifestyle Health - Episode 344

    Episode 344

    Show notes

    Dr. Pamela Cipriano shares her journey from being an ICU nurse to a trailblazer in functional medicine. She discusses her personal experiences with Lyme disease, the importance of hydration, nutrition, and the impact of chronic illnesses. Dr. Cipriano emphasizes the need for a holistic approach to health, focusing on root causes and lifestyle changes, while also sharing insights on the effects of COVID and the importance of proper diet and hydration. In this conversation, Dr. Pamela Cipriano discusses the implications of vaccination, particularly in relation to health concerns and the effects of spike proteins. She emphasizes the importance of Vitamin B12 and mitochondrial function in overall health, while also addressing oxidative stress and innovative therapies for chronic conditions. The discussion extends to the future of Lyme disease treatment and the challenges in diagnosing and treating Bartonella, highlighting the need for proper education and awareness in managing tick-borne diseases.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    · Dr. Cipriano transitioned from nursing to functional medicine to help patients achieve better health.

    · Her personal experience with her son's Lyme disease shaped her focus on chronic illnesses.

    · Chronic diseases often have triggers that can be identified and addressed.

    · Water intake is crucial for overall health and disease prevention.

    · Nutrition plays a significant role in managing inflammation and chronic diseases.

    · Avoiding processed foods and sugars is essential for maintaining health.

    · The quality of food, including meat and dairy, impacts health outcomes.

    · Functional medicine requires a thorough understanding of a patient's history and lifestyle.

    · COVID-19 has highlighted the importance of diet and hydration in recovery.

    · The healthcare system often prioritizes medication over holistic health solutions. Vaccination can lead to health problems in some individuals.

    · Spike proteins may persist and cause long-term health issues.

    · Vitamin B12 is crucial for nervous system health.

    · Mitochondria play a vital role in cellular function and energy production.

    · Oxidative stress accelerates aging and cellular damage.

    · IV therapies can significantly aid in recovery from chronic conditions.

    · Bartonella can mimic severe neurological disorders like ALS.

    · Proper testing is essential for diagnosing tick-borne diseases.

    · Education is critical for effective treatment of Lyme disease.

    · Innovative therapies are emerging for chronic health issues.

    Chapters

    00:00 Introduction to Dr. Pamela Cipriano

    01:32 Journey into Functional Medicine

    02:52 Personal Experience with Lyme Disease

    04:55 Understanding Chronic Illnesses

    06:57 The Importance of Water and Hydration

    13:43 Nutrition and Anti-Inflammatory Foods

    19:28 Insights on COVID and Long COVID

    20:26 The Impact of Vaccination and Health Concerns

    21:53 Understanding Spike Proteins and Their Effects

    22:38 The Importance of Vitamin B12

    23:54 Mitochondrial Function and Health

    25:53 Oxidative Stress and Its Management

    27:45 Innovative Therapies for Chronic Conditions

    30:37 The Future of Lyme Disease Treatment

    32:55 Bartonella: Diagnosis and Treatment Challenges

    39:56 Navigating Tick-Borne Diseases

    To learn more about Dr. Pamela Cipriano: Facebook: https://www.facebook.com/Dr.Pamela.Cipriano Instagram: https://www.instagram.com/practicehealthwellness YouTube: https://www.youtube.com/@dr.pamelacipriano1329 Website: https://www.thepracticeofhealthandwellness.com

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    37 min
  20. Unlocking Cognitive Potential: The Nootropic Journey - Episode 343

    Episode 342

    Show notes

    In this episode of the Glad and Longevity Podcast, Jeff Gladden and Jonathan Roseland delve into the world of biohacking and nootropics. They discuss the inspiration behind Roseland's journey into cognitive enhancement, the quest for effective smart drugs, and the role of nicotine in boosting creativity. The conversation also touches on the importance of a systems biology approach to personal development, emphasizing the need for personalized strategies in optimizing cognitive function and overall health. In this conversation, Jonathan Roseland and Jeff Gladden explore the themes of risk-taking, spirituality, psychedelics, and memory enhancement. They discuss the importance of embracing risk in various aspects of life, the spiritual dimensions of longevity, and the potential benefits of psychedelics for personal growth. Additionally, they delve into effective memory enhancement techniques and the power of the mind in shaping personal agency and identity.

    For Audience

    Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!

    Takeaways

    Nootropics can provide instant motivation and clarity.

    The quest for effective smart drugs is ongoing.

    Nicotine is recognized as a creativity enhancer.

    Personal development often requires a systems biology approach.

    Finding your edge is essential for personal growth.

    Racetams are a promising class of nootropics.

    Biohacking can lead to meaningful personal development.

    Understanding individual biodiversity is crucial in nootropic use.

    Living young for a lifetime involves taking calculated risks.

    Systems biology can streamline the process of finding effective nootropics. Finding your edge in life can lead to growth.

    Embracing risk is essential for learning and joy.

    Spiritual practices contribute to longevity and well-being.

    Psychedelics can facilitate profound personal insights.

    Memory enhancement techniques can significantly improve recall.

    The mind operates on both conscious and subconscious levels.

    Self-love and safety are crucial for personal development.

    Agency over one's life choices is empowering.

    Engaging in challenging activities keeps the mind sharp.

    Personal growth often requires stepping outside of comfort zones.

    Chapters

    00:00 Introduction to Biohacking and Nootropics

    05:57 The Quest for Smart Drugs

    12:05 Nootropics: Instant Motivation and Clarity

    17:55 Exploring Racetams and Their Effects

    23:45 The Role of Nicotine in Cognitive Enhancement

    30:05 Systems Biology Approach to Personal Development

    37:27 Riding the Edge: Embracing Risk in Life

    45:40 The Spiritual Dimension of Longevity

    51:39 Psychedelics and Spiritual Growth

    58:32 Memory Enhancement Techniques

    01:11:36 The Power of the Mind and Personal Agency

    To learn more about Jonathan Roseland:Email: jr@limitlessmindset.com Website: https://www.limitlessmindset.com/ Facebook: https://www.facebook.com/limitlessmindset

    Reach out to us at:

    Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

    Gladden Longevity Podcast Disclosures

    • Production & Independence

    The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas.

    Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements.

    • Medical Disclaimer

    The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content.

    The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options.

    Use of information from this podcast and any linked materials is at the listener's own risk.

    • Podcast Guest Disclosures

    Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team.

    • Sponsorships & Affiliate Disclosures

    To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes.

    We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented.

    • Additional Note on Content Integrity

    All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

    1 hr 8 min

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